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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya JPSriwijaya Paediatrica Indonesiana Jurnal Pengabdian Masyarakat: Humanity and Medicine
Dewi Rosariah Ayu
Department Of Child Health, Sriwijaya University Medical School/Dr. Mohammad Hoesin Hospital, Palembang, South Sumatera
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health

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PERILAKU MAKAN DAN AKTIVITAS FISIK MAHASISWA PENDIDIKAN DOKTER DI MASA PANDEMI COVID-19 Alisha Milenia Utami; Ardesy Melizah Kurniati; Dewi Rosariah Ayu; Syarif Husin; Iche Andriyani Liberty
JURNAL KEDOKTERAN DAN KESEHATAN Vol 8, No 3 (2021)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.V8I3.13829

Abstract

Indonesia berada pada peringkat ke-2 kasus konfirmasi tertinggi COVID-19 di ASEAN pada Agustus 2020. Obesitas merupakan salah satu risiko penyebab komplikasi akibat COVID-19. Perilaku makan yang tidak sehat dan tidak aktif berolahraga dapat menyebabkan obesitas. Pada masa pandemi, perkuliahan dilakukan secara daring untuk melindungi mahasiswa dari penularan. Penelitian ini bertujuan untuk mengetahui gambaran perilaku makan dan aktivitas fisik pada mahasiswa Pendidikan Dokter Fakultas Kedokteran di Palembang selama pandemi COVID-19. Jenis penelitian yang digunakan adalah penelitian deskriptif dengan desain studi cross-sectional. Data didapatkan dari hasil pengisian kuisioner secara mandiri yang dibagikan kepada responden melalui Google Form. Sebanyak 276 orang mengisi kuesioner. Hasil penelitian menunjukkan bahwa responden mengalami penurunan aktivitas fisik (85,1%) dan duduk selama ?8 jam saat kuliah online (62,0%). Sebagian besar mengonsumsi karbohidrat <3 porsi/hari (63,0%), sayur <3 porsi/hari (84,1%) dan buah <2 porsi/hari (59,8%). Sebanyak 44,9% mahasiswa memiliki frekuensi makan utama 2 kali sehari dan frekuensi makan kudapan 3 kali sehari. Masih terdapat mahasiswa yang mengalami penurunan aktivitas fisik dan memiliki perilaku makan yang tidak sesuai anjuran Pedoman Gizi Seimbang selama masa pandemi COVID-19.
SKRINING THALASSEMIA PADA REMAJA DI DESA TANJUNG PERING KECAMATAN INDRALAYA OGAN ILIR Dewi Rosariah Ayu
Jurnal Pengabdian Sriwijaya Vol 8, No 2 (2020)
Publisher : Lembaga Pengabdian pada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37061/jps.v8i2.12431

Abstract

Indonesia merupakan salah satu negara yang memiliki penduduk pembawa Thalassemia sekitar 3-8%, bahkan di beberapa daerah mencapai 10%. Thalassemia sulit dideteksi karena bersifat asimtomatik sehingga peranan skrining sebagai deteksi dini sangat diperlukan. Skrining Thalassemia diperlukan untuk mencegah dan memutus rantai penyakit kelainan darah merah ini. Tujuan pengabdian masyarakat ini untuk meningkatkan kesadaran dan pemahaman awam di Desa Tanjung Pering, khususnya pada siswa-siswi SMAN 1 Indralaya Utara terhadap gejala penyakit Thalasemia dan penanganannya. Metode penelitian deskriptif kuantitatif dengan teknik pengambilan data cross sectional telah dilakukan sejak bulan September sampai dengan November 2019. Subjek penelitian terdiri dari siswa-siswi di SMAN 1 Indralaya Utara kelas 10 dan 11 yang memenuhi kriteria inklusi. Dari 51 orang siswa yang bersedia ikut serta saat penyuluhan dan pemeriksaan laboratorium darah didapatkan 9 orang (9.6%) yang dicurigai sebagai pembawa sifat Thalassemia.
Upper arm circumference measurement for detecting overweight and obesity in children aged 6-7 years Dewi Rosariah Ayu; Aditiawati Aditiawati; Julius Anzar; Erial Bahar
Paediatrica Indonesiana Vol 57 No 1 (2017): January 2017
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (288.37 KB) | DOI: 10.14238/pi57.1.2017.23-9

Abstract

Background Obesity is a worldwide problem and is associated with increased risk of metabolic syndrome. Nutritional status in children has traditionally been determined by body mass index (BMI) scores, but with limitations. Upper arm circumference measurement may be a better predictor of energy, protein, and fat storage, as well as a simpler method for screening overweight and obesity in children.Objective To determine the diagnostic value of upper arm circumference compared to BMI for detecting overweight and obesity in children aged 6-7 years.Methods This diagnostic study with a cross-sectional design was performed from September to October 2015 at 16 primary schools in Palembang, Indonesia. We measured the heights, weights, and upper arm circumferences, and calculated BMIs of 2,258 children. Receiver-operator characteristic (ROC) curve analysis was used to find an optimal upper arm circumference cut-off point to detect overweight and obesity. Diagnostic value was calculated by using a 2x2 table analysis.Results The prevalences of overweight and obesity were 5.8% and 11.7%, respectively. The optimal upper arm circumference cut-off points for detecting overweight in children aged 6-7 years was 185 mm (sensitivity 88.1% and specificity 78.3%), and for obesity was 195 mm (sensitivity 90.15% and specificity 86.65%). Upper arm circumference had a strong correlation with BMI.Conclusion Upper arm circumference measurement is an accurate method fordistinguishing between normoweight, overweight, and obesity in children aged 6-7 years.
3-year survival rate in acute lymphoblastic leukemia: comparison of ALL-2006 and ALL-2013 Protocols Avyandita Meirizkia; Dewi Rosariah Ayu; Raden Muhammad Indra; Dian Puspita Sari
Paediatrica Indonesiana Vol 61 No 3 (2021): May 2021
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi61.3.2021.155-64

Abstract

Background With advances in supportive and risk-stratified therapy, the 5-year survival rate of acute lymphoblastic leukemia has reached 85.5%. The ALL-2006 treatment protocol was modified and renamed the ALL-2013 protocol, with dose and duration changes. Objective To compare outcomes of the ALL-2006 and ALL-2013 protocols, with regards to mortality, remission, relapse, and three-year survival rates. Methods This was retrospective cohort study. Subjects were acute lymphoblastic leukemia (ALL) patients treated from 2011 to 2018 in Mohamad Hoesin Hospital, Palembang, South Sumatera. The three-year survival rates, relapse, remission rates and comparison of ALL-2006 and ALL-2013 protocols were analyzed with Kaplan-Meier method. Results Mortality was significantly correlated with age at diagnosis <1 year and >10 years, hyperleukocytosis, and high-risk disease status. Patients aged 1 to 10 years, with leukocyte count <50,000/mm3 and standard-risk status had significantly higher likelihood of achieving remission. Mortality was not significantly different between the ALL-2006 protocol group [70.6%; mean survival 1,182.15 (SD 176.89) days] and the ALL-2013 protocol group [72.1%; mean survival 764.23 (SD 63.49) days]; (P=0.209). Remission was achieved in 39.2% of the ALL-2006 group and 33% of the ALL-2013 group (P>0.05). Relapse was also not significantly different between the two groups (ALL-2006: 29.4% vs. ALL-2013: 17.9%; P>0.05). Probability of death in the ALL-2006 group was 0.3 times lower than in the ALL-2013 group (P<0.05), while that of the high-risk group was 3 times higher. Remission was 2.19 times higher in those with leukocyte <50,000/mm3 compared to those with hyperleukocytosis. In addition, relapse was significantly more likely in high-risk patients (HR 2.96; 95%CI 1.22 to 7.19). Overall, the 3-year survival rate was 33%, with 41.7% in the ALL-2006 group and 30.7% in the ALL-2013 group. Conclusion Three-year survival rate of ALL-2006 protocol is higher than that of ALL-2013 protocol but is not statistically significant. Age at diagnosis <1 year and >10 years, hyperleukocytosis, and high-risk group are significantly correlated with higher mortality and lower remission rates. However, these three factors are not significantly different in terms of relapse.
Pelatihan skrining tumbuh kembang bagi Guru PAUD di Kota Palembang Lestari, Hertanti Indah; Kesuma, Yudianita; Karmila, Ariesti; Ayu, Dewi Rosariah; Akbari, Atika
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 6 No 1 (2025): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V6I1.151

Abstract

Child development disorders can affect the next stage of growth and development and can have an impact on the future. Good and proper care for children who are in the growth and development period will help children to grow healthy and be able to achieve their optimal abilities so that they can contribute better to society. The main objectives of this community service are to improve the skills of Early Childhood Education (ECE) teachers to detect early growth and development disorders, reduce the number of advanced growth and development disorders, and optimize child growth and development with early intervention. The method of service carried out in this activity is in the form of training on the use of the PRIMAKU application for 1000 ECE teachers in Palembang City and assessed using pre-test and post-test questionnaires. The results of the counseling showed an increase in results in two benchmarks, an increase in participant knowledge based on the results of the pre-test and post-test correct answers by 17.03%. Furthermore, it is expected that PAUD teachers who have attended the training can apply the use of the PRIMAKU application for early detection of growth and development disorders or delays in early childhood.
Kidney dysfunction in children with thalassemia Lestari, Hertanti Indah; Rahmawati, Eka; Ayu, Dewi Rosariah; Fitriana, Eka Intan; Sari, Dian Puspita
Paediatrica Indonesiana Vol. 65 No. 4 (2025): July 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.4.2025.337-45

Abstract

Background Children with thalassemia are at risk for kidney dysfunction due to chronic anemia, frequent blood transfusions, iron retention, and use of iron chelating agents. Cystatin C, an endogenous marker for assessing estimated glomerular filtration rate (eGFR), a novel biomarker for the early detection of kidney failure, has been reported to be potentially superior to the commonly used serum creatinine. Objective To evaluate various creatinine- and cystatin C-based formulas for eGFR to detect kidney dysfunction in children with thalassemia. Methods This was a cross-sectional study on children (age <18 years) with thalassemia. Kidney dysfunction was defined as eGFR <90 mL/minute/1.73 m2. Hyperfiltration was defined as eGFR >150 ml/minute/1.73 m2. This study compared the proportion of kidney dysfunction as determined using various creatinine- and cystatin C-based eGFR formulas, comprising the creatinine-based Schwartz formula, the cystatin C-based Filler formula, the creatinine-cystatin C-based New CKID formula, and the creatinine-cystatin C-based Schwartz formula. Results The median age of the 152 study subjects was 11.0 (range 2.0-18.0) years. When using the creatinine-based Schwartz formula, none of the subjects had kidney dysfunction. Kidney dysfunction was found in 21.7% of subjects when using the cystatin C-based Filler formula, in 26.3% of subjects when using the creatinine-cystatin C-based (New CKID) formula, and 59.9% of subjects using the creatinine-cystatin C-based Schwartz formula. When using the creatinine-based Schwartz formula, 38.2% subjects experienced hyperfiltration no hyperfiltration was found by when using other eGFR formulas. There was low correlation between creatinine and cystatin C (r=0.195; P=0.016). There was only mild agreement in eGFR between the creatinine-based Schwartz formula and the cystatin C-based Filler formula (k=0.195; P<0.001). Conclusion The proportion of kidney dysfunction in children with thalassemia based on eGFR calculation using cystatin C- and creatinine-cystatin C-based formulas ranged from 21.7% to  59.9%. No kidney dysfunction was found using a creatinine-only-based eGFR formula, whereas hyperfiltration was a common finding. Hence, more than one parameter should be considered for early detection of kidney dysfunction in thalassemia.
Co-Authors Aditiawati Aditiawati Akbari, Atika Alisha Milenia Utami Ardesy Melizah Kurniati Avyandita Meirizkia Dian Puspita Sari Dian Puspita Sari Eka Intan Fitriana eka rahmawati Erial Bahar Hertanti Indah Lestari, Hertanti Indah Iche Andriyani Liberty, Iche Andriyani Julius Anzar Karmila, Ariesti Raden Muhammad Indra Syarif Husin Yudianita Kesuma, Yudianita