Ekawaty Lutfia Haksari
Departemen Ilmu Kesehatan Anak Fakultas Kedokteran, Keperawatan, Dan Kesehatan Masyarakat Universitas Gadjah Mada/RSUP. Dr. Sardjito, Yogyakarta

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Risk factors of neonatal mortality of referred babies with birthweight of 1000- < 2500 grams Ekawaty Lutfia Haksari, Dian Murni Wardhani, Setya Wandita
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 03 (2009)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (301.215 KB)

Abstract

Background: Almost 16% from all of the total births in the developing countries are low birthweight babies. Low birthweight babies are an important contribution in neonatal mortality and morbidity worldwide, and contribute to almost 70% of the total neonatal deaths. Proportion of the low birthweight babies in the developing countries is 90% of the total low birthweight babies around the world, which is 20 million annually. Mortality of babies weighing 1000-&lt; 2500 grams in Dr. Sardjito Hospital reached 51.4%, and that of referred babies was 74.6%. Objectives: This research was aimed to find out and measure the risk factors that contribute to the mortality of referred low birthweight babies in the neonatal period. Methods: A hospital-based research with case-control study design was done to discover the risk factors that related to the neonatal mortality of the referred babies with birthweight of 1000- &lt; 2500 grams. Data were collected from babies medical records treated in the Maternal-Perinatal Installation of Dr. Sardjito Hospital in 2005 to 2007. Target population of this research was the mentioned above who died at the age of 0-28 days. Variable analysis to find out the correlation between the risk factors and the mortality used odds.ratio (OR), 95% confidence interval (95% CI), and the significance level with Chi-square test. To measure the risk factors that contributed on the mortality multivariate logistic regression analysis was used. Result: This study involved 190 babies (95 cases and 95 control) weighing between 1000 and &lt; 2500 grams, who were referred to Dr. Sardjito Hospital. Several subjects were excluded, 23 babies because of going home on selfrequest, 24 because of incomplete status, 76 because of severe congenital anomaly, and 34 were extremely low birthweight babies. Sepsis (OR: 5.054, 95%CI2.433-11.198), HMO(OR:4.461, 95%CI1.595-10.497), hypoglycemia (OR: 3.358, 95%CI1.679-6.715), and hypothermia (OR: 2.221, 95%CI1.082-4.560) were the risk factors of mortality. Conclusion: Sepsis, HMO, hypoglycemia, and hypothermia increased the mortality risk of babies weighing 1000-&lt; 2500 grams referred to Dr. Sardjito Hospital, Yogyakarta. Key words: low birthweight baby -risk factor -referral -neonatal death
Risk factors of neonatal mortality of referred babies with birthweight of 1000- < 2500 grams Dian Murni Wardhani, Setya Wandita Ekawaty Lutfia Haksari
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 03 (2009)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (301.215 KB)

Abstract

Background: Almost 16% from all of the total births in the developing countries are low birthweight babies. Low birthweight babies are an important contribution in neonatal mortality and morbidity worldwide, and contribute to almost 70% of the total neonatal deaths. Proportion of the low birthweight babies in the developing countries is 90% of the total low birthweight babies around the world, which is 20 million annually. Mortality of babies weighing 1000-< 2500 grams in Dr. Sardjito Hospital reached 51.4%, and that of referred babies was 74.6%. Objectives: This research was aimed to find out and measure the risk factors that contribute to the mortality of referred low birthweight babies in the neonatal period. Methods: A hospital-based research with case-control study design was done to discover the risk factors that related to the neonatal mortality of the referred babies with birthweight of 1000- < 2500 grams. Data were collected from babies' medical records treated in the Maternal-Perinatal Installation of Dr. Sardjito Hospital in 2005 to 2007. Target population of this research was the mentioned above who died at the age of 0-28 days. Variable analysis to find out the correlation between the risk factors and the mortality used odds.ratio (OR), 95% confidence interval (95% CI), and the significance level with Chi-square test. To measure the risk factors that contributed on the mortality multivariate logistic regression analysis was used. Result: This study involved 190 babies (95 cases and 95 control) weighing between 1000 and < 2500 grams, who were referred to Dr. Sardjito Hospital. Several subjects were excluded, 23 babies because of going home on selfrequest, 24 because of incomplete status, 76 because of severe congenital anomaly, and 34 were extremely low birthweight babies. Sepsis (OR: 5.054, 95%CI2.433-11.198), HMO(OR:4.461, 95%CI1.595-10.497), hypoglycemia (OR: 3.358, 95%CI1.679-6.715), and hypothermia (OR: 2.221, 95%CI1.082-4.560) were the risk factors of mortality. Conclusion: Sepsis, HMO, hypoglycemia, and hypothermia increased the mortality risk of babies weighing 1000-< 2500 grams referred to Dr. Sardjito Hospital, Yogyakarta. Key words: low birthweight baby -risk factor -referral -neonatal death
Penerapan Metode Bermain sebagai Stimulasi untuk Meningkatkan Perkembangan Anak Catur Yulinawati; Djauhar Ismail; Ekawaty Lutfia Haksari; Dewi Rokhanawaty
Jurnal Keperawatan Jiwa (JKJ): Persatuan Perawat Nasional Indonesia Vol 8, No 2 (2020): Mei 2020
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (290.427 KB) | DOI: 10.26714/jkj.8.2.2020.147-152

Abstract

Anak usia dini merupakan masa-masa kritis bagi perkembangan nya sebagaimana terjadi pesatnya perkembangan otak sebagai dasar dari pembangunan keterampilan dan kecerdasan berkelanjutan untuk masa depan anak yang terjadi sebelum usia 6 tahun yang dipengaruhi oleh rangsangan dan pengasuhan. Perkembangan anak yang tumbuh di negara berpenghasilan menengah dan rendah gagal mencapai potensi perkembangan, faktor penyebab diantaranya terdapat kemiskinan, kekurangan gizi dan stimulasi yang tidak memadai yang beresiko meningkatkan kematian dan morbiditas. Stimulasi yang dilakukan sesuai dengan tahap belajar anak dengan menerapkan stimulasi dengan metode bermain yang menyenangkan sehingga tujuan peningkatan perkembangan tercapai. Tujuan dari penelitian ini untuk melakukan review pengaruh stimulasi dengan cara bermain terhadap perkembangan pada anak. Sumber data mereview artikel didapatkan dari Pubmed, ProQuest dan Wiley dengan total 390 artikel. adapun artikel yang berhasil di review terdapat 3 artikel sesuai dengan Kriteria inklusi 1) Anak, 2) Bermain, 3) Stimulasi, 4) Perkembangan. Studi appraisal dengan menggunakan Critical Appraisal Skills Program (CASP), metode sintesis dengan menggunakan Patient Intervention Comparison Outcome (PICO). Hasil dari review 3 artikel ini adalah pentingnya melakukan stimulasi dengan bermain seperti menggambar, bermain bola, bernyanyi, tebak kata sangat berpengaruh untuk meningkatkan perkembangan serta memperkuat landasan dalam melakukan penelitian. Kata kunci: anak, bermain, perkembangan, stimulasi METHOD METHOD OF APPLICATION PLAY AS STIMULATION TO IMPROVE CHILDREN'S DEVELOPMENT ABSTRACTEarly childhood is a critical period for development as rapid brain development occurs as a basis for the development of skills and intelligence for the future of children that occur before the age of 6 years, which is influenced by stimulation and care. The development of children who grow up in middle and low income countries fails to achieve development potential, the contributing factors include poverty, malnutrition and inadequate stimulation that is at risk of increasing death and morbidity. Stimulation is carried out in accordance with the learning stages of children by applying stimulation with play methods that are fun so that the goal of increasing development is achieved. The purpose of this research is to review the effect of stimulation by playing on development in children. Data Sources and Methods : The data source for reviewing articles was obtained from Pubmed, ProQuest and Wiley with a total 390 articles. There are articles successful in reviews there are 3 articles according to the Inclusion criteria 1) Children, 2) Playing, 3) Stimulation, 4) Development. Appraisal study using the Critical Appraisal Skills Program (CASP), synthesis method using Patient Intervention Comparison Outcome (PICO). The results of the review of these 3 articles are the importance of stimulation by playing such as drawing, playing ball, singing, guessing words very influential to improve development and strengthen the foundation in conducting research. Keywords: child, development, play, stimulation
Faktor Risiko Trauma Lahir MM. Tri Widiyati; Setya Wandita Tunjung Wibowo; Ekawaty Lutfia Haksari
Sari Pediatri Vol 15, No 5 (2014)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp15.5.2014.294-300

Abstract

Latar belakang. Kemajuan di bidang pelayanan obstetri berhasil menurunkan kejadian trauma lahir. Namun, trauma lahir masih merupakan salah satu penyebab morbiditas dan mortalitas pada neonatal. Banyak faktor risiko yang berperan dalam trauma lahir.Tujuan. Mengetahui faktor risiko trauma lahir.Metode. Penelitian kasus-kontrol di bangsal Perinatal Rumah Sakit Dr Sardjito, Yogyakarta, mulai Januari 2004 sampai Desember 2008. Kriteria inklusi adalah semua neonatus dengan trauma lahir dan kriteria eksklusi adalah jika ada anomali kongenital dan data medis tidak lengkap. Kontrol adalah neonatus tanpa trauma lahir. Kasus adalah semua neonatus dengan trauma lahir, dan keduanya memenuhi kriteria inklusi dan eksklusi. Data dikumpulkan dari rekam medis yang berkaitan dengan data ibu, bayi, dan faktor risiko yang diduga berhubungan dengan trauma lahir.Hasil. Di antara 6678 neonatus, 47 mengalami trauma lahir, yaitu trauma kepala 27 (57%), trauma tulang 13(28%), saraf perifer 10(21,3%), saraf pusat 7(14,8%), dan 3 lainnya (6%). Faktor risiko trauma lahir adalah paritas (OR 1,3;CI95%=0,5-3,4; p=0,625), umur kehamilan (OR 1,5;95%CI=0,2-9,6; p=1,00), berat lahir (OR 1,4;95%CI=0,3-6,5; p=0,100), lingkar kepala (OR 1,5;95%CI=0,4-5,0; p=0,76), malpresentasi (OR 3,6;95%CI=0,4-30,3;p=0,244), presentasi bokong (OR 3,9;95%CI=1,0-14,8; p=0,049), presentasi muka (OR 2,0;95%CI=1,7-2,5; p=1,00), vakum ekstraksi (OR 10,1;95%CI=1,2-88,3; p=0,037), versi ekstraksi (OR 3,1;95%CI=0,3-31,3; p=0,62), penyulit persalinan (OR 11,4;95%CI=2,2-60,2; p=0,004), letak lintang (OR 1,0;95%CI=0,2-5,2; p=1,000), dan seksio kaisaria (OR 0,4;95%CI=0,1-0,8; p=0,017).Kesimpulan. Faktor risiko trauma lahir adalah presentasi bokong, persalinan dengan penyulit dan vakum ekstraksi, sedangkan kelainan presentasi tidak berhubungan dengan trauma lahir. Seksio kaisaria merupakan faktor protektif terhadap terjadinya trauma lahir.
Pertambahan Berat Badan Pasca Penutupan Patent Duktus Arteriosus secara Transkateter Dewi Hartaty; Noormanto Noormanto; Ekawaty Lutfia Haksari
Sari Pediatri Vol 17, No 3 (2015)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp17.3.2015.180-4

Abstract

Latar belakang. Patent duktus arteriosus (PDA) merupakan salah satu penyakit jantung bawaan asianotik yang paling banyakdijumpai pada anak. PDA dapat memengaruhi pertumbuhan anak dan menyebabkan malnutrisi pada anak dan malnutrisi yangterjadi merupakan faktor risiko mortalitas dan morbiditas pada anak.Tujuan. Mengetahui pertambahan berat badan sebelum dan sesudah dilakukan tindakan penutupan duktus pada anak dengan PDAsecara transkateter dan untuk mengetahui faktor-faktor yang berpengaruh terhadap pertambahan berat badan setelah dilakukanpenutupan PDA secara transkateter.Metode. Penelitian observasional pre dan post test design dengan menggunakan data rekam medis. Anak dengan PDA yangdilakukan penutupan secara transkateter. Z-score berat badan menurut umur dinilai sebelum dan pada saat 1, 3, 6, dan 12 bulansetelah penutupan dan dilakukan analisis menggunakan repeated ANOVA test. Faktor-faktor yang memengaruhi pertambahanberat badan 3 bulan setelah penutupan dianalisis menggunakan chi square dan regressi logistik.Hasil. Terdapat 43 anak usia <5 tahun dengan PDA diikutkan dalam penelitian dari Januari 2005 sampai Juni 2011. Sebelumpenutupan 76,7% (33) anak dengan z-score berat badan/umur < -2 SD. Didapatkan perbaikan rerata z-score berat badan/umursebelum dan saat 1, 3, 6, dan 12 bulan setelah penutupan (-2,63 vs -2,41, -2,14, -1,92 and -1,56; p<0,05). Jenis kelamin, umur,z-score berat badan/umur sebelum penutupan, berat lahir, hipertensi pulmonal, gagal jantung, pekerjaan orang tua, pendidikanibu dan penghasilan orang tua tidak berhubungan dengan pertambahan berat badan 3 bulan setelah penutupan.Kesimpulan. Penutupan defek secara transkateter pada anak usia <5 tahun dengan PDA akan memberikan peningkatan z-scoreberat badan berdasarkan umur.
Faktor Prediktor Kematian Neonatus dengan Malformasi Anorektal Pasca Operasi Ariadne Tiara Hapsari; Tunjung Wibowo; Alifah Anggraini; Setya Wandita; Ekawaty Lutfia Haksari
Sari Pediatri Vol 23, No 5 (2022)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp23.5.2022.323-9

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Latar belakang. Anorectal malformation (ARM) atau imperforate anus atau malformasi anorektal (MAR) atau atresia ani merupakan kelainan bawaan yang sering ditemui. Kematian neonatus MAR yang tidak segera terdiagnosis masih terjadi. Kesakitan neonatus MAR pasca operasi dikaitkan dengan infeksi saluran kencing dan gangguan pertumbuhan, serta dapat terjadi perforasi usus serta septikemia yang dapat menyebabkan kematian. Tujuan. Penelitian ini bertujuan untuk mengidentifikasi faktor prediktor yang memengaruhi kematian neonatus dengan MAR pasca operasi.Metode. Dilakukan penelitian kohort retrospektif pada data neonatus malformasi anorektal pasca operasi di RSUP dr. Sardjito Yogyakarta antara Januari 2013 - Desember 2019. Data karakteristik berupa jenis kelamin, usia kehamilan, berat lahir, usia operasi, fistula, VACTERL, penyakit jantung bawaan, sepsis, dan usia ibu.Hasil. Diperoleh 188 neonatus MAR dari 9736 neonatus yang dirawat di bangsal perinatal dan NICU pada periode Januari 2013- Desember 2019. Analisis bivariat diperoleh variabel: usia kehamilan, berat lahir, penyakit jantung bawaan, dan sepsis merupakan faktor prediktor kematian pada neonatus MAR. Dari analisis multivariat didapatkan variabel yang dapat menjadi faktor prediktor kematian neonatus MAR pasca operasi adalah penyakit jantung bawaan (OR:3,91;CI 95% :1,52-10,03) dan sepsis (OR:3,16; CI 95% :1,45-6,89).Kesimpulan. Penyakit jantung bawaan dan sepsis merupakan faktor prediktor kematian pada neonatus malformasi anorektal.
Faktor Prognostik Kematian Bayi Berat Lahir Sangat Rendah di Rumah Sakit Rujukan Tingkat Tersier Tunjung Wibowo; Ekawaty Lutfia Haksari; Setya Wandita
Sari Pediatri Vol 13, No 6 (2012)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (173.399 KB) | DOI: 10.14238/sp13.6.2012.401-5

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Latar belakang. Bayi berat lahir sangat rendah (BBLSR) masih merupakan tantangan dalam upaya menurunkan angka kematian neonatal. Beberapa faktor risiko telah terbukti meningkatkan risiko kematian BBLSR, seperti berat lahir dan umur kehamilan. Besarnya variasi tingkat perawatan di neonatal intensive care unit(NICU) juga akan berkontribusi terhadap risiko kematian.Tujuan. Melakukan pengaruh beberapa faktor maternal, fetal, kondisi bayi dan parameter pemeriksaan pendukung terhadap kematian BBLSR.Metode. Penelitian kohort prospektif dilakukan di bangsal Perinatologi RSUP Dr. Sardjito Yogyakarta dari tanggal 1 Februari 2007 sampai Agustus 2010. Semua bayi yang dirawat dengan berat lahir lebih dari 500 g, tanpa kelainan kongenital yang lethal dan dapat diikuti sampai diijinkan pulang dimasukkan sebagai subjek penelitian. Data faktor prognostik kematian dikumpulkan dengan formulir yang sudah terkode. Dilakukan analisis dengan logistik regresi untuk mengetahui pengaruh faktor prognosis terhadap kejadian kematian BBLSR.Hasil. Didapatkan 394 bayi lahir BBLSR yang diikutsertakan ke dalam penelitian, 33 (8%) bayi dikeluarkan karena pulang sebelum diijinkan. Angka kematian BBLSR 62,3%. Dari hasil analisis multivariat didapatkan variabel yang dapat menjadi faktor prognostik kematian BBLSR adalah berat lahir <1000 g ( OR:5; 95% CI: 2,3 – 10,7), nilai Apgar menit pertama <4 (OR: 6: 95% CI: 3,1 – 12), penggunaan ventilator (OR; 8,3; 95% CI: 4,3 – 16), sepsis (OR: 12; 95% CI: 3,8 – 37,9) dan kasus rujukan (OR: 3,1; 95% CI: 1,4 – 6,6)Kesimpulan. Berat lahir <1000 g, nilai Apgar menit pertama <4, penggunaan ventilator, sepsis dan kasus rujukan merupakan faktor prognostik yang secara bermakna meningkatkan kematian BBLSR
Risk factors for hearing loss in neonates Ni Luh Putu Maharani; Ekawaty Lutfia Haksari; I Wayan Dharma Artana
Paediatrica Indonesiana Vol 55 No 6 (2015): November 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.366 KB) | DOI: 10.14238/pi55.6.2015.328-32

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Background An estimated 6 of 1,000 children with live births suffer from permanent hearing loss at birth or the neonatal period. At least 90% of cases occur in developing countries. Hearing loss should be diagnosed as early as possible so that intervention can be done before the age of 6 months. Objective To determine risk factors for hearing loss in neonates. Methods We performed a case-control study involving 100 neonates with and without hearing loss who were born at Sanglah Hospital, Denpasar from November 2012 to February 2013. Subjects were consisted of 2 groups, those with hearing loss (case group of 50 subjects) and without hearing loss (control group of 50 subjects). The groups were matched for gender and birth weight. We assessed the following risk factors for hearing loss: severe neonatal asphyxia, hyperbilirubinemia, meningitis, history of aminoglycoside therapy, and mechanical ventilation by Chi-square analysis. The results were presented as odds ratio and its corresponding 95% confidence intervals. Results Seventy percent of neonates with hearing loss had history of aminoglycoside therapy. Multivariable analysis revealed that aminoglycoside therapy of 14 days or more was a significant risk factor for hearing loss (OR 2.7; 95%CI 1.1 to 6.8; P=0.040). There were no statistically significant associations between hearing loss and severe asphyxia, hyperbilirubinemia, meningitis, or mechanical ventilation. Conclusion Aminoglycoside therapy for >=14 days was identified as a risk factor for hearing loss in neonates.
Developmental delay in 3-month-old low birth weight infants with hyperbilirubinemia Wiradharma Wiradharma; I Gusti Ayu Trisna Windiani; Ekawaty Lutfia Haksari
Paediatrica Indonesiana Vol 53 No 4 (2013): July 2013
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (103.325 KB) | DOI: 10.14238/pi53.4.2013.228-31

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Backgrourui Developmental delay may be due to a variety offactors occurring during the prenatal, perinatal, or postnatalperiods, one of which is hyperbilirubinemia.Objective To evaluate the impact ofhyperbilirubinemia on infantdevelopmental delay.Methods A prospective cohort study was conducted from March toJuly 2011. Subjects were low birth weight infants with and withouthyperbilirubinemia. Developmental delay was measured using theMullen Scales of Early Learning. Data was analyzed by Chi squaretest and relative risks were calculated. Logistic regression analysiswas performed to assess factors associated with developmentaldelay. Differences were considered statistically significant for Pvalues < 0.05.Results Forty-six low birth weight infants were enrolledin this study, 23 with hyperbilirubinemia and 23 withouthyperbilirubinemia. The relative risk (RR) for developmentaldelay in the hyperbilirubinemia group was 2.08 (95%CI 0.51 to8 .40). Multivariate analysis revealed that hyperbilirubinemia didnot significantly influence developmental delay (RR 1.45; 95%CI0.29 to 7.31). However, small for gestational age with or withouthyperbilirubinemia significantly influenced developmental delay(RR 12.13; 95%CI 2.43 to 60.56).Conclusion Hyperbilirubinemia in low birth weight infants isn ot a risk factor for developmental delay at the age of 3 months.However, being small for gestational age with or withouthyperbilirubinemia significantly influences the likelihood ofdevelopmental delay.
Relationship between bottle feeding in supine position in infants and the presence of asthma among preschoolers Pertiwi Febriana Chandrawati; Roni Naning; Ekawaty Lutfia Haksari
Paediatrica Indonesiana Vol 49 No 3 (2009): May 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (101.734 KB) | DOI: 10.14238/pi49.3.2009.182-5

Abstract

Background Asthma is a common chronic respiratory disease.The risk factors of asthma are allergic factors, familial atopy,race, gender, and smoking during pregnancy. Other risk factorsare gastroesophageal reflux and micro-aspiration which causebronchospasm and bronchial hyperreactivity due to repeatedairway irritation.Objective To determine the association between bottle feedinggiven in supine position before sleep time in the first year of lifewith asthma in 4 to 7 years old.Methods A case control study was conducted on pediatricpatients from Sardjito Hospital and Muhammadiyah kindergarten, Yogyakarta. Two structured questionnaires were used; the first identified the case group (asthma) and control group (nonasthma), whereas the second one identified whether the subjects had bottle feeding in supine position in the first year of life or not.Results 122 subjects were studied, 62 subjects in asthma groupand 60 in control group. In asthma group, feeding in supineposition before sleep time in the first year had OR of 2.45 (95%CI 1.21 to 6.93), whereas regurgitation when bottle-feeding insupine position had OR of 4.53 (95% CI 1.54 to 13.16). Suddencry when bottle-feeding in supine position had OR of 5.02 (95%CI 1.69 to 15.71). Asthma in the family increased risk of asthma[OR 3.12 (95% CI 1.16 to 6.50)] and atopicfamily has OR 3.25(95% CI 1.01 to 6.27).Conclusion Bottle feeding in supine position before sleep timeduring first year oflife is associated with occurrence of asthma inpreschool children.