Muherdiyatiningsih Muherdiyatiningsih
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PENGARUH PEMBERIAN TABLET BESI DAN VITAMIN E PADA KADAR HEMOGLOBIN DAN STATUS BESI WANITA USIA SUBUR YANG DIDUGA MENDERITA THALASEMIA KARIER M. Saidin; Sukati Sukati; Muherdiyatiningsih Muherdiyatiningsih; Effendi Rustan
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 26 No. 2 (2003)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v26i2.1430.

Abstract

THE EFFECT OF IRON PILL SUPPLEMENTATION ADDED WITH VITAMIN E (ALPHA-TOCOPHEROL) TO HEMOGLOBIN AND IRON STATUS OF CHILDBEARING AGE WOMEN SUSPECTED SUFFERING FROM CARRIER THALASSEMIA.Background: Anemia control programme among pregnant women had been conducting for about three decades, but prevalence of anemia still considered high. It was reported by Nutrition and Food Research Centre (2000) that 37.4% of childbearing women indicated fragility of red blood cell membrane wich assumed related to anemia. One of the vitamins which have positive effect to the wall of red blood cells is vitamin E through its rolle as antioxidant. It was recommended to conduct a study to determine the effect of supplementation of iron pill, "Ferro sulfate" (60 mg elemental iron with 25 mg folic acid) added with vitamin E (20 mg a-tocopherol) to hemoglobin level and iron status of childbearing age of women.Methods: The study design was "Intervention with quacy experiment trial".  The study sites covered 10 villages in Cianjur district of West Java. A total of 210 childbearing age women (19-45 years old) with indication of fragility of red blood cell membrane which was determined by procedure of NESTROF (Naked Eye Single Test Tube Red Cell Osmotic Fragility), divided into two groups (105 women/group). Group I received one iron pill daily and vitamin E twice a week for 10 weeks. While group II received Iron pill only, without vitamin E. Data collection was conducted before and after intervention.Results: After 10 weeks intervention, the average of Hb increament of group I (0.4 g/dl) was slightly higher than that of group II (0.3 g/dl). There was improvement of serum ferritin of both groups with increament 4.3 mg/dl for group I and 7.2 mg/dl for group II. Vitamin E status of both groups still considered low: 3.1 mg/L for group I and 3.1 mg/L for group II. Normal value of serum vitamin E is 5.0 mg/L.Conclusions: Vitamin E (20 mg of a-tocopherol) which was given twice a week bisides daily supplementation of iron pill (60 mg elemental iron of sulfas ferrosus + 25 mg folic acid) for 10 weeks increased the effectiveness of Hb synthesis 1.5 times than that of supplementation of iron only without vitamin E.Keywords: iron supplementation, Hb level, iron status, vitamin E status, NESTROF, fragility of cells membrane 
KEKURANGAN VITAMIN A PADA KELOMPOK BAYI DAN FAKTOR YANG BERHUBUNGAN DI KABUPATEN BOGOR Muherdiyatiningsih Muherdiyatiningsih; Nuning M. Kiptiyah; Muhilal Muhilal; Sri Martuti; Frank T. Wieringa; Marjoleine A. Dijkhuizen
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 26 No. 2 (2003)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v26i2.1432.

Abstract

VITAMIN A DEFICIENCY AND ITS RELATED FACTORS IN INFANTS IN BOGOR DISTRICT.Background: Based on clinical indicators, vitamin A deficiency in Indonesia is not a public health problem because the prevalence of xerophthalmia has been decreased to 0.34%. But, this decrease has not been followed by a decrease of marginal deficiency of vitamin A in vulnerable groups, especially infants.Methods: The cross-sectional baseline study was conducted at Bogor District. The aim of the study was to collect information about the vitamin A status of the breastfed infant, and to look for a relationship between many factors related to it. The samples were 183 breastfed infants aged 2-0 months without chronic disease, congenital disease, severe PEM nor twins. The chi-square and the prevalence odds ratio (POR) at the 95% confidence interval were used to measure the association between variables. Multiple logistic regression analysis was used to measure the closest factors to infant's vitamin A status.Results: The study showed that 54.1% of breastfed infants were at risk of vitamin A deficiency. Based on bivariate analysis, there are two significant independent variables related to infants vitamin A status, which are maternal vitamin A status and infant infection status. Multiple logistic regression analysis showed that infection status is the closest factor to vitamin A deficiency in infants, followed by maternal vitamin A status and breast feeding frequency. There are no significant association between supplementary feeding, age, nutritional status and the infant's vitamin A status.Conclusions: Marginal vitamin A deficiency in infants aged 2-10 months is still a public health problem in the research area. The infection status is the closest factor to vitamin A deficiency in infants, followed by maternal vitamin A status and breast feeding frequency.Keywords: vitamin A deficiency, breast feeding, infection, complementary feeding, infant 
SINDROME METABOLIK PADA ORANG DEWASA GEMUK DI WILAYAH BOGOR Muherdiyatiningsih Muherdiyatiningsih; Fitrah Ernawati; Rustan Effendi; Susilowati Herman
Penelitian Gizi dan Makanan (The Journal of Nutrition and Food Research) Vol. 31 No. 2 (2008)
Publisher : Persagi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/pgm.v31i2.1518.

Abstract

Metabolic Syndrome Among Obese Adults In Bogor Area.Background: Metabolic syndrome, also known by the insulin resistance syndrome, is a common metabolic disorder that result from the increasing prevalence of obesity. Little information exists on the prevalence of the metabolic syndrome in Indonesia.Objectives: To find out proportion of metabolic syndrome and factors related to-demographic and potentially modifiable lifestyle factors among obese adults in Bogor area.Methods: Metabolic syndrome, as defined by the US National Cholesterol Education Program - Adult Treatment Panel III (NCEP-ATP III) criteria, were evaluated in two districts in Bogor sample of 221 overweight and obese (Body Mass Index > 25 kg/m2) women and men aged 30-55 years who participated in the correlational study on Profile of the Body and Serum Fats Distribution and Physical Activity among adults with BMI > 25 kg/m2 in Bogor rural and urban, 2003.Results: The metabolic syndrome was present in 36.2 percent of 221 men and women aged 31-55 years which have BMI > 25 kg/m2. The syndrome was significantly more frequent in men (44%) than women (28.6%) [P=0.017]. The syndrome was present in 92.3, 62.9, and 40.3 percent of central obesity, low HDL-cholesterol, and high triglycerides level, respectively. Age of the subject > 44 years, the men factor, physical inactivity, and Waist-Hip Ratio (WHR) > 0.93 were the significantly risk factors associated with increased odds of the metabolic syndrome.Conclusions: The metabolic syndrome was present in high prevalence of the two subdistricts in Bogor obese adults. However, upon thinking about the syndrome was associated with several modifiable lifestyle factors (physical activity, WHR), there was an opportunity to reduce proportion of metabolic syndrome by increasing physical activity that also make lower WHR.Keywords: metabolic syndrome, adulthood obesity, NCEP-ATP III, risk factors