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All Journal Science and Technology Indonesia Reswara: Jurnal Pengabdian Kepada Masyarakat Jurnal Natural Journal Of Carbazon
Murniana Murniana
Chemistry Department, Faculty of Mathematics and Natural Sciences, Syiah Kuala University
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Journal : Journal Of Carbazon

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The antinematicidal activity of vitamin E and its derivatives on Sterinernema feltieae Khairan, Khairan; Idroes, Rinaldi; Murniana, Murniana; Diah, Muhammad
Journal of Carbazon Vol 1, No 2 (2023): December 2023
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jocarbazon.v2i1.35776

Abstract

Vitamin E is found naturally in some foods, and also available as a dietary supplement. "Vitamin E" is the fat-soluble compounds with distinctive antioxidant activities. The vitamin E acts as an antioxidant, which protects cell membranes. Sterinernema feltieae was selected as a test organism is because this organism is a complex organism and can be used as a model for whole organisms. The objective of this study is to evaluate the activity of vitamin E and its derivatives on Sterinernema feltieae. The results showed that the derivative of vitamin E (C37H55NO3) was most active against S. feltiae with the LD50 value was 207.77 M, followed by vitamin E (C29H50O2) with the LD50 value was 209.09 M. These results indicated that derivative of vitamin E (C37H55NO3) exerts more potent toxicity than vitamin E against Sterinernema feltieae.
Isolation and Screening of Endophytic Fungi from Soursop (Annona muricata L.) Leaves: Potential Sources of Antimicrobial Compounds Nurhaida, Nurhaida; Murniana, Murniana; Amrina, Bella Septie; Rasyid, Syarifah AB
Journal of Carbazon Vol 1, No 1 (2023): June 2023
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jokarbazon.v1i1.32733

Abstract

Endophytic fungi, which reside within plant tissues, offer a unique ecological perspective due to their mutually beneficial relationship with host plants. Soursop (Annona muricata L.) leaves, known for their medicinal properties, contain bioactive compounds that may be produced by endophytic fungi. This study aimed to isolate endophytic fungi from soursop leaves and evaluate their potential as antimicrobial compound producers. Twenty endophytic fungal isolates were obtained from soursop leaves using Potato Dextrose Agar (PDA) supplemented with leaf extract. Out of these isolates, eight demonstrated antimicrobial activity against the tested microorganisms. Notably, the extract produced by SLE16 exhibited inhibitory effects against Gram-negative bacteria, while isolates SLE7, SLE8, and SLE14 showed antifungal activity against Candida albicans. Furthermore, isolates SLE18, SLE19, and SLE20 displayed significant inhibition of Trichophyton rubrum growth. The extracellular extracts derived from these endophytic fungi exhibited hydrophilic properties and formed inhibition zones larger than 15 mm, indicating their potential as antimicrobial compounds. These findings highlight the potential of endophytic fungi isolated from soursop leaves as valuable sources of novel antimicrobial compounds
Co-Authors Amrina, Bella Septie Arpini, Mifta ATANTA, JAINURSUMARMI SAFRULLAH Bakhtiar , Bakhtiar Binawati Ginting Dewi Karlina Rusly Diah, Muhammad Humaira, Cut Jessica Kartini Hasballah Khairan Khairan Maidiani, Tika Marlina Marlina Misrahanum Misrahanum Muslem, Abdul Halim Nurhaida Nurhaida Putra, Ferry Syah Rahmazani, Shinta Rampengan, Derren DCH Rasyid, Syarifah AB Rezeki, Rena Novita Rinaldi Idroes Sadli Sadli