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Trigona sp. Propolis Ethanolic Extract Decreased Chloramphenicol-induced Serum Glutamic Oxaloacetic Transaminase and Alkaline Phosphatase Levels of Rats (Rattus novergicus) Chanif Mahdi; Anna Zukiaturrahmah; Dyah Ayu Oktavianie Ardhiana Pratama; Putranty Widha Nugraheni
Indonesian Journal of Cancer Chemoprevention Vol 9, No 3 (2018)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev9iss3pp110-117

Abstract

Liver has an important role in detoxification of toxins such as xenobiotic which could interfere the function of liver. Chloramphenicol is an antibiotic widely used,despite of its toxicity potentials. The enhancement of free radicals in the body could suppress antioxidant activity. Propolis of Trigona sp. has been known to contain very high amount of antioxidants. The enhanced serum glutamic oxaloacetic transaminase (SGOT) and alkaline phosphatase (ALP) levels in serum is used as marker of liver damage due to the increase of free radicals. The purpose of this study was to observe the effect of Trigona sp. propolis ethanolic extract on SGOT and ALP levels in rats (Rattus novergicus) pretreated by chloramphenicol to induce liver damage. Test animals used for this research were male rats aged 8-12 weeks divided into five treatment groups: negative controlgroup (normal), positive control group (induced by 400 mg/kgBW chloramphenicol), first therapy group, second therapy group, third therapy group induced by chloramphenicol with and propolis extract with the dose of 8 mg, 16 mg, and 24 mg, respectively. Chloramphenicol was injected subcutaneously for 14 days, whereas propolis extract were administered orally for 21 days. The level of SGOT and ALP was determined using spectophotometry. The results showed that propolis extract could reduce levels of SGOT and ALP. Dose of 24 mg/kg was the effective dose to decrease levels of SGOT and ALP significantly (p<0.01). Hence, it may be concluded that the ethanol extract of propolis could be used as herbal therapy in rats model of liver damage.Keywords : ALP, liver, chloramphenicol, propolis, SGOT
Case report: Demodicosis in a Chow-chow dog at Yours Veterinary Clinic in Padang Panjang City Ridho Gelagar, Ario; Sukmawati, Yofa; Ramadhan, Juliadi; Aulia, Usma; Zukiaturrahmah, Anna
Basic and Applied Nursing Research Journal Vol 4 No 2 (2023): Basic and Applied Nursing Research Journal (BANRJ)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/banrj.04.02.07

Abstract

Demodecosis, also known as Red Mange, Acarus Mange, and Follicular Mange, is a skin disease caused by the mite Demodex canis. Demodecosis infection can occur in dogs of all ages. This study aims to diagnose and treat the infection of Demodex sp in chow-chow dogs. Clinical signs include generalized alopecia, scales, and crusts found on the body's surface, followed by dehydration symptoms, poor skin turgor, and long CRT. Supporting examinations to determine demodecosis infection are carried out using the deep skin scrapping test method. Next, a hematological exam was carried out. The hematology examination interpreted the blood analysis results to indicate that the dog had normochromic microcytic anemia. A decrease in RBC, hemoglobin, and hematocrit indicates anemia. A low MCV indicates Microcytic, and normochromic is due to a normal MCHC. Treatment is carried out by administering ivermectin, diphenhydramine HCl, and longamox.
Enucleation of Bulbus Oculi in Domestic Cats Patients with Orbital Tumors Ramadhan, Juliadi; Nafis S, Muhammad; Ridho Gelagar, Ario; Aulia, Usma; Zukiaturrahmah, Anna; Sukmawati, Yofa
Basic and Applied Nursing Research Journal Vol 4 No 2 (2023): Basic and Applied Nursing Research Journal (BANRJ)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/banrj.04.02.06

Abstract

The eye is an essential organ for living things, as one of the five senses of the eye is very vulnerable to infectious or non-infectious diseases. The orbital tumor is one of the disorders in the cat's eye that can attack the eye muscles, nerves, and lacrimal glands. This study aims to diagnose and treat the enucleation of bulbus oculi in domestic cats and patients with orbital tumors. This activity was carried out at the Veterinary Practice "Drh. Juliadi Ramadhan, M.Si." Jl. Payakumbuh-Lintau No. 12 Regency 50 City, West Sumatra Province. The results showed that one of the treatments for orbital tumor cases can be done by enucleation of the oculi bulk. This operation uses a subconjunctival method to remove the eye, the nictitating membrane, and a little eyelid by minimizing the removal of extraocular muscle tissue. After surgery, intense treatment is carried out by maintaining the sanitation of the cage and administering anti-inflammatory drugs, antibiotics, and vitamins.
Diagnosis of Ancylostomiasis in a Cat Ridho Gelagar, Ario; Aulia Tri Yuska, Dian; Ramadhan, Juliadi; Zukiaturrahmah, Anna; Aulia, Usma; Sukmawati, Yofa
Basic and Applied Nursing Research Journal Vol. 6 No. 2 (2025): Basic and Applied Nursing Research Journal (BANRJ)
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/banrj.06.02.03

Abstract

Ancylostomiasis is an important gastrointestinal helminthiasis in cats with zoonotic potential. This case report describes ancylostomiasis in a seven-year-old domestic female cat presented to Yours Animal Clinic, Padang Panjang, West Sumatra, with diarrhea and lethargy. Clinical examination, fecal analysis, and hematological evaluation were performed to establish the diagnosis. Fecal examination using native smear, flotation, centrifugation, and McMaster counting techniques revealed Ancylostoma sp. eggs with an eggs-per-gram (EPG) value of 2,200, indicating a mild infection intensity. Physical examination showed a low body condition score, dull hair coat, mild dehydration, and diarrhea. Hematological analysis demonstrated decreased red blood cell count, hemoglobin, hematocrit, granulocytes, and platelets, accompanied by increased lymphocytes, monocytes, mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC), consistent with anemia and an inflammatory response secondary to helminth infection. Based on these findings, the cat was diagnosed with ancylostomiasis and treated with anthelmintics, fluid therapy, antibiotics, and supportive care. This case highlights the integration of clinical, parasitological, and hematological findings in the diagnosis of ancylostomiasis in cats and underscores the importance of routine deworming, appropriate husbandry, environmental sanitation, and periodic fecal examination to reduce the risk of infection and potential zoonotic transmission.
CASE REPORT: MANUAL REPOSITIONING MANAGEMENT OF UTERINE PROLAPSE IN CATTLE AT SMALLHOLDER FARMS IN LIMAPULUH KOTA REGENCY Zukiaturrahmah, Anna; Putri, Ulfa Rahmi; Darwis; Aulia, Usma; Ramadhan, Juliadi; Rezeki, Sri
Buletin Veteriner Udayana Bul. Vet. Udayana. February 2026 Vol. 18 No. 1
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2026.v18.i01.p22

Abstract

Uterine prolapse is a reproductive disorder in cattle that requires prompt and effective management to ensure survival, recovery, and preservation of fertility. Uterine prolapse is defined as the protrusion of the uterus through the vulva, exposing the mucosal surface. This case report describes the occurrence of uterine prolapse in a cow and its therapeutic management. Clinical examination revealed that the uterus was protruding outside the pelvic cavity, accompanied by weakness and anorexia. The patient was diagnosed with a uterine prolapse. The treatment consisted of manual uterine repositioning, followed by vulvar suturing. Supportive therapy, including antibiotics, multivitamins, calcium supplementation, and topical antiseptics, was administered for seven days. The cow showed favorable recovery and complete resolution of the uterine prolapse. The prevention of recurrent uterine prolapse in cattle includes adequate uterine repositioning, temporary vulvar suturing, correction of postpartum metabolic disorders, appropriate nutritional management, and close postpartum monitoring.
IDENTIFICATION OF FORMALIN CONTENT IN SOME FRESH SALTWATER FISH AT X TRADITIONAL MARKET, PAYAKUMBUH Aulia, Usma; Putri, Ulfa Rahmi; Zukiaturrahmah, Anna; Ramadhan, Juliadi; Darwis; Rezeki, Sri
Buletin Veteriner Udayana Bul. Vet. Udayana. February 2026 Vol. 18 No. 1
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2026.v18.i01.p11

Abstract

Fish is a food source with high protein content and is relatively more affordable compared to other animal-based protein sources. A common issue is the misuse of hazardous substances to prevent quality deterioration and increase profit, such as formalin. This study aimed to identify the presence of formalin in fresh marine fish sold at Traditional Market X, Payakumbuh, to ensure food quality and safety for public consumption. Formalin testing was conducted on 10 samples, each weighing 10 g. Twenty milliliters of aquadest were added to each sample, followed by homogenization using a stomacher. The samples were then centrifuged at 3000 rpm for two minutes. After centrifugation, 10 mL of the supernatant from each sample was transferred into test tubes. Each tube was added with 3 drops of 0.5% phenylhydrazine, 2 drops of 5% sodium nitroprusside, and 3 drops of 10% NaOH, and the results were observed. The results showed that none of the samples contained formalin, as indicated by the absence of color change; all samples remained reddish-orange after reagent addition. Therefore, fresh marine fish sold at Traditional Market X Payakumbuh, were confirmed to be free from formalin and safe for consumption. Routine monitoring by the government is recommended to prevent the misuse of hazardous substances such as formalin in food products.