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All Journal Jurnal Entropi Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Ilmiah Sesebanua
Mohammad Adam Mustapa
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Chemistry Medicine & Pharmacology Other

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PENGARUH EKSTRAK METANOL DAUN PALIASA (Kleinhovia hospita, Linn) TERHADAP LAMBUNG MENCIT Mustapa, Mohammad Adam
Jurnal Entropi Vol 1, No 2, 2006
Publisher : Jurnal Entropi

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Abstract

The research about the effect of extract methanol ? Paliasa? leaves (Kleinhovia hospita, Linn) to gastric of mice have been done, which is given orally to improve the scientific data in development of ? Paliasa? Plant as tradisional drug for some kinds of desease. This research has used lest animals of fifteen male micethat divided into 5 groups. Groups I,II,III have been given suspension of extract methanol with 5 % w/v, 10 % w/v and 15 % w/v during 7 days. Group IV has been given acetosal suspension 0,195 % as comparement. Group V have been given Na-CMC as control. Observasion have been done in daya of 8 th then operated the astric of mece which is separated and observea mether there is a gastric ulcer such as blood spot perforation. The result showed that there is no effect to the gastrik of mice by the methanol extract of paliasa leaves.
STANDARISASI PARAMETER SPESIFIK EKSTRAK METANOL BIJI KEBIUL (CAESALPINIA BONDUC L.) SEBAGAI BAHAN BAKU OBAT HERBAL TERSTANDAR Mustapa, Mohammad Adam; Abdulkadir, Widy Susanti; Halid, Indriany Femina
Journal Syifa Sciences and Clinical Research Vol 2, No 1 (2020): Maret 2020
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.3731/jsscr.v2i1.4209

Abstract

The determination of specific parameters standardization of knicker nut (Caesalpinia BonducL.) methanol extract as the standardized herbal medicine raw materials has been carried out to ensure the quality improvement of traditional medicines and the efficacy of the plant. The purpose of this research is to determine the specific parameters of knicker nut extract so that it can be consumed as herbal medicines that have been scientifically tested. The knicker nut extract was obtained from the extraction employing the maceration method with methanol as the solvent. Specific parameters testing included extract identity, extract organoleptic, dissolved compound in certain solvents, along with extract chemical test. The results of extract identity testing show that the Latin name is CaesalpiniaBonducL. with the nut as the used part of the plant. The organoleptic test reveals that the plant is in the form of thick extract, blackish-brown in color, bitter, has pungent smell/typical smell of knicker nut, contains water-soluble compound of 10.33% with the standard deviation ±1.154707755, N-hexane-soluble compound of 3.33% with the standard deviation ±1.154707755, and methanol-soluble compound of 17.33% with the standard deviation ±3.511886957. Moreover, the flavonoids wavelengths are 382 nm (band I) and 262 nm (band II).
EVALUASI PENYIMPANAN OBAT DI INSTALASI FARMASI RSUD SAYANG RAKYAT MAKASSAR Siti Winanshy Kairupan; Mohammad Adam Mustapa; Wiwit Zuriati Uno; Widy Susanti Abdulkadir; Nur Ain Thomas; Ayu Indira
Jurnal Ilmiah Sesebanua Vol. 9 No. 2 (2025): Jurnal Ilmiah Sesebanua
Publisher : Politeknik Negeri Nusa Utara

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Abstract

Penyimpanan obat di rumah sakit merupakan aspek penting dalam manajemen farmasi yang berfungsi menjaga mutu, stabilitas, dan keamanan sediaan hingga digunakan oleh pasien. Penyimpanan yang tidak memenuhi standar dapat menyebabkan penurunan kualitas, kontaminasi, bahkan menjadikan obat berpotensi toksik sehingga membahayakan keselamatan pasien. Penelitian ini bertujuan untuk mengevaluasi penyimpanan berdasarkan kesesuaian tata ruang dan metode penyimpanan obat di Instalasi Farmasi RSUD Sayang Rakyat Makassar berdasarkan standar yang ditetapkan dalam Permenkes RI Nomor 72 Tahun 2016 tentang Standar Pelayanan Kefarmasian di Rumah Sakit. Penelitian ini menggunakan metode deskriptif observasional dengan pendekatan kuantitatif. Data dikumpulkan melalui observasi langsung di ruang penyimpanan, wawancara dengan kepala instalasi dan apoteker penanggung jawab, serta telaah dokumen seperti Standar Operasional Prosedur (SOP) dan catatan penyimpanan. Instrumen penelitian berupa lembar checklist yang disusun berdasarkan indikator Permenkes No. 72 Tahun 2016. Hasil penelitian menunjukkan bahwa Instalasi Farmasi RSUD Sayang Rakyat telah menerapkan metode First Expired First Out (FEFO) dan First In First Out (FIFO) secara konsisten dalam proses distribusi dan penataan obat. Pengelompokan obat dilakukan berdasarkan bentuk sediaan (padat, cair, dan semi padat) serta disusun secara alfabetis untuk memudahkan pencarian. Persentase kesesuaian aspek tata ruang, metode penyimpanan, dan fasilitas berada pada kategori baik, meskipun masih terdapat kendala berupa keterbatasan ruang dan jumlah rak penyimpanan. Secara keseluruhan, sistem penyimpanan obat di Instalasi Farmasi RSUD Sayang Rakyat Makassar telah sesuai dengan standar pelayanan kefarmasian rumah sakit, namun masih diperlukan peningkatan sarana fisik untuk menjaga mutu obat dan meningkatkan efisiensi pelayanan
Co-Authors Ayu Indira Halid, Indriany Femina Nur Ain Thomas Siti Winanshy Kairupan Widy Susanti Abdulkadir Widy Susanti Abdulkadir Wiwit Zuriati Uno