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The Most Dominant Predictability Factor of Boey Score on The Level of Mortality in Perforation Gaster Boey Score 1 and Boey Scores 2 Patients in RSUD Dr Soetomo Surabaya Sandi Halim Naga Saputra; Vicky Sumarki Budipramana; Marjono Dwi Wibowo
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 10 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i10.357

Introduction: The Boey score is the most commonly used scoring system for risk stratification because of its simplicity and high predictive value for mortality and morbidity in cases of gastric perforation. This score is widely used in daily practice because it only assesses 3 assessment components; namely the onset of perforation, shock at first admission, and comorbid disease; which is easy to do and has a fairly good accuracy. In Boey score 2, the mortality rate is still high, so research on the factors that most influence mortality at Boey Score 2 needs to be done.Methods: This study uses secondary data from medical records of patients who meet criteria of inclusion and exclusion. This study is a comparative test using a cohort analytic observational study design (longitudinal retrospective), comparing the components of the Boey score which is the most influential in predicting the mortality rate in gastric perforated patients. Boey score 1 and Boey score 2 at RSUD Dr. Soetomo SurabayaResults: Total subject of the study was 65 people, consisting of 43 men (66.2%) and 22 women (33.8%). The Boey score was 16 people (24.6%) with a Boey score of 1 and 49 people (75.4%) with a Boey score 2.From the Boey score component, 49 people (75.4%) were obtained with the onset of perforation> 24 hours, 31 people (47.7%) with preoperative shock, and 34 people (52.3%) with comorbidities. Comorbidity in study subjects included hypertension in 17 people (26.2%), diabetes mellitus in 4 people (6.2%), heart disease in 4 people (6.2%), lung disease in 5 people (7.7%), and kidney disease in 7 people. people (10.8%)Conclusion: Shock is the most dominant Boey Score predictability factor that affects the mortality rate in gastric perforation patients with Boey score 1 and Boey score 2.

Profile of Maxillofacial Fracture Patients at General Hospital in Surabaya Bonfilio Neltio Ariobimo; Marjono Dwi Wibowo; Abdurachman Abdurachman
Biomolecular and Health Science Journal Vol. 4 No. 1 (2021): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v4i1.26723

Introduction: Maxillofacial fractures can be caused by blunt trauma or sharp trauma. The purpose of this study was to identify the characteristics in patients with maxillofacial fractures who were treated in the Head and Neck Surgery Division of Dr. Soetomo General Academic Hospital, Surabaya during 2016.Methods: The research design was cross-sectional from patients with maxillofacial fractures. Those variables were evaluated are gender, age, type of etiology, site of maxillofacial fracture, gender and type of etiology based incidence, age and type of etiology based incidence. Data presented descriptively.Results: From 68 patients, consisted of 57 (83.82%) male, average age of 30.1 years old. The most common type of etiology was traffic accidents (92.64%), most common site of fractures were mandibular (33.33%), gender associated with the type of etiology was men who experienced traffic accidents (79.41%), and the age associated with the most types of events was ages 26-45 years with traffic accidents (47.05%).Conclusion: Maxillofacial fractures still become the problem that mainly cause is traffic accidents which occurred mostly in male and mandibular fracture as the most common site of fracture.

The Most Dominant Predictability Factor of Boey Score on The Level of Mortality in Perforation Gaster Boey Score 1 and Boey Scores 2 Patients in RSUD Dr Soetomo Surabaya Sandi Halim Naga Saputra; Vicky Sumarki Budipramana; Marjono Dwi Wibowo
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 10 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i10.357

Introduction: The Boey score is the most commonly used scoring system for risk stratification because of its simplicity and high predictive value for mortality and morbidity in cases of gastric perforation. This score is widely used in daily practice because it only assesses 3 assessment components; namely the onset of perforation, shock at first admission, and comorbid disease; which is easy to do and has a fairly good accuracy. In Boey score 2, the mortality rate is still high, so research on the factors that most influence mortality at Boey Score 2 needs to be done.Methods: This study uses secondary data from medical records of patients who meet criteria of inclusion and exclusion. This study is a comparative test using a cohort analytic observational study design (longitudinal retrospective), comparing the components of the Boey score which is the most influential in predicting the mortality rate in gastric perforated patients. Boey score 1 and Boey score 2 at RSUD Dr. Soetomo SurabayaResults: Total subject of the study was 65 people, consisting of 43 men (66.2%) and 22 women (33.8%). The Boey score was 16 people (24.6%) with a Boey score of 1 and 49 people (75.4%) with a Boey score 2.From the Boey score component, 49 people (75.4%) were obtained with the onset of perforation> 24 hours, 31 people (47.7%) with preoperative shock, and 34 people (52.3%) with comorbidities. Comorbidity in study subjects included hypertension in 17 people (26.2%), diabetes mellitus in 4 people (6.2%), heart disease in 4 people (6.2%), lung disease in 5 people (7.7%), and kidney disease in 7 people. people (10.8%)Conclusion: Shock is the most dominant Boey Score predictability factor that affects the mortality rate in gastric perforation patients with Boey score 1 and Boey score 2.

MECHANISM OF APOPTOSIS INHIBITION TO SQUAMOUS CELL CARCINOMA OF ORAL CANCER IN CISPLATIN TREATMENT Dwi Wibowo, R Marjono; Perdanakusuma, David S; Tanggo, Eddy Herman
Folia Medica Indonesiana Vol. 53 No. 1 (2017): JANUARY - MARCH 2017
Publisher : Universitas Airlangga

This study was to approve the increased secretion of Hsp 70, DNA damage, and inhibitor apoptosis protein in cisplatin therapy which influence apoptosis of oral cancer cell and to know mechanism of molecular pathology. This study was an in vitro experimental laboratory using Randomized Block Design. Cell culture of oral cancer divided from cisplatin resistance cancer cell and cancer cell never induce cisplatin. Two group of cancer cell would be given cisplatin therapy. Secretion of Hsp 70, DNA damage, Inhibitor of apoptosis protein, and apoptosis index would be examined. Cisplatin resistance cancer cell group showed lower apoptosis than never induce cisplatin cancer cell. Elevated secretion of Hsp 70 in cisplatin therapy group (p= 0.000, b=0.881). Lower secretion of DNA damage protein in cisplatin resistance cancer cell and it was not going apoptosis. In path regression analysis, cisplatin was significans through IAP pathway (p=0.000, b=0.726) to apoptosis. All type of cell cultures were also significans through IAP pathway (p=0.000, b=0.496) to apoptosis. Elevated IAP secretion influenced apoptosis (b= 1.000). In conclusion, cisplatin used IAP pathway to apoptosis. All type of cell cultures also used IAP pathway to apoptosis. Cisplatin resistance cell culture had stronger effect to IAP and IAP increased inhibition to apoptosis.

Profile of Patients with Bile Duct Injury in RSUD Dr. Soetomo Period January 224-December 2024 Santi, Santi; Danardono, Edwin; Wibowo, Marjono Dwi
Journal of World Science Vol. 4 No. 1 (2025): Journal of World Science
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jws.v4i1.1295

Surgical procedures involving the biliary system are among the most common in digestive surgery. Advances in laparoscopic techniques have increased the frequency of bile duct injuries (BDI), a major contributor to morbidity and mortality, remarkably when unrecognized during surgery, which occurs in 25% to 32.4% of cases. This study describes the characteristics of BDI patients treated at RSUD Dr. Soetomo Surabaya from January to December 2024. Employing an observational analytical design with a cross-sectional approach, data were collected from the medical records of 26 patients meeting inclusion and exclusion criteria. Patients who underwent laparoscopic surgery had a shorter average Length of Stay (LOS) of 12.91 days compared to 23.57 days for those with open surgery. Mortality was observed exclusively among patients with a history of open surgery, notably in BDI type E4 cases. These findings highlight the importance of timely recognition and effective management of BDIs to mitigate their significant impact on patient outcomes.

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