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All Journal e-Journal Pustaka Kesehatan STOMATOGNATIC- Jurnal Kedokteran Gigi MKGK (Majalah Kedokteran Gigi Klinik) (Clinical Dental Journal) UGM UNEJ e-Proceeding Health Notions
Swasthi Prasetyarini
Bagian Ilmu Kedokteran Gigi Dasar, Fakultas Kedokteran Gigi, Universitas Jember
Dentistry Education Health Professions Library & Information Science Medicine & Pharmacology Nursing Public Health

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Pengaruh Pajanan Radiasi Sinar-X dari Radiografi Panoramik terhadap pH Saliva (The Effects of Panoramic Dental X-Ray Radiation Exposure on Salivary pH) Nungky Tias Susanti; Swasthi Prasetyarini; Amandia Dewi Permana Shita
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background: Panoramic radiograph is a dental radiodiagnosis which is often used to assist in establishing diagnosis and determining treatment plans using low dose x-ray radiation exposure.The basic working principle of panoramic radiograph is using ionizing radiation which causes ionization reactions on the affected objects. Radiation area in patients undergoing panoramic radiograph involves salivary glands, thus it generates certain impacts in the quality and quantity of saliva produced. Aim: To analyze the effects of panoramic dental x-ray radiation exposure on salivary pH. Research Method: This study used quasi experimental research method with pre and post test only control group design. Eight people were chosen as samples based on inclusion and exclusion criteria. Saliva testing was performed to the chosen samples pre and post panoramic dental x-ray radiation exposure. The research data were measured using paired t-test statistical analysis. Result: There wassignificant difference on salivary pH pre and post panoramic dental x-ray radiation exposure (p<0,05). Conclusion: Panoramic dental x-ray exposure can decrease salivary pH. Keywords: Panoramic radiograph, Salivary pH
Pengaruh Bisphenol-A (BPA) terhadap Kadar Insulin Pada Hepar Tikus Wistar Jantan Rizky Purboningtyas; Zahreni Hamzah; Swasthi Prasetyarini
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 16 No 2 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v16i2.23089

Abstract

Bisphenol-A (BPA) is a synthetic chemical substance in the form of monomers which is commonly used as plastic constituents. BPA is often found in household appliances, food and beverage containers, and in dental sealants and acrylic base dentures. BPA can contaminate or enter the human body mostly through oral route or swallowed along with food consumed. It is known that BPA exposure through the oral route can cause several diseases, and one of them is endocrine and metabolic problems, which is Diabetes Mellitus. This study was to analyze the decrease of insulin levels in the liver of male Wistar rats after being exposed by BPA. 18 adult male Wistar rats were divided into 3 groups. Group I (control 1) was not given any treatment, only acclimatized for 7 days. Group II (control 2) was treated with sterile aquadest orally for 28 days. Group III (treatment group) was given oral BPA treatment with a dose of 20 mg / kg body weight for 28 days. After sacrificed, the hepar was homogenated and the insulin level was determined by ELISA. Data were analyzed with One Way Anova test and LSD test. Bisphenol-A (BPA) with a dose of 20 mg/kgBB exposed for 28 days can reduce on hepar insulin levels in adult male Wistar rats.
Pengaruh BPA (Bisphenol A) terhadap Kadar Insulin dalam Serum Darah Tikus Wistar Jantan Fitria Nurhabiba Agustine; Swasthi Prasetyarini; Zahreni Hamzah
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 16 No 1 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v16i1.19959

Abstract

BPA is a synthetic material that widely used in basic material of PVC making. PVC is needed in production of household appliances, food container, mineral water bottles, feeding bottles and dental sealant. BPA is known as one of EDCs which have an effect to increase insulin levels on blood. Furthermore, BPA could lead to DMT2. The objective was to determine the effect of BPA on blood insulin levels in adult male wistar rats. 18 male wistar rats were divided into 3 groups. BPA solution was made by dissolve 20 mg/kgBB crystal BPA into corn oil. Group 1 (K1) not given any treatment and dissected in day-0. Group 2 (K2) given aquadest treatment orally for 28 days and dissected in day-29. Group 3 (P) given BPA solution treatment orally for 28 days and dissected in day-29. The treatment given once a day on 09.00 AM. The blood collected after 12 hours fasting. Blood collecting procedure done with the rats were anasthetized first with eter 10% through inhalation and then dissect the rats until the heart is exposed. Blood was collected from the heart for 3 ml and were sentrifugated to get the serum. Insulin examination done by ELISA on serum that has been collected. Data were analyzed by One Way Anova test and Post hoc Test LSD. BPA with 20 mg/kgBB dose increasing blood serum insulin levels on adult male wistar rats by 1,38 mIU/L.
Pengaruh pajanan radiasi sinar x dari radiografi periapikal terhadap penurunan jumlah fibroblas pada soket pencabutan gigi tikus wistar Ghina Lady Salsabila; Swasthi Prasetyarini; Budi Yuwono
MKGK (Majalah Kedokteran Gigi Klinik) (Clinical Dental Journal) UGM Vol 6, No 1 (2020)
Publisher : Fakultas Kedokteran Gigi, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mkgk.58241

Abstract

Radiografi periapikal adalah radiografi intraoral yang mencakup gigi geligi dan jaringan sekitarnya. Penggunaannya menimbulkan efek negatif bagi tubuh yaitu adanya kerusakan seluler. Salah satu sel yang memiliki radiosensitif tinggi adalah fibroblas. Fibroblas merupakan agen utama dalam proses penyembuhan luka pasca pencabutan. Penelitian ini bertujuan untuk mengetahui pengaruh pajanan radiasi sinar x dari radiografi periapikal terhadap penurunan jumlah fibroblas pada soket pencabutan gigi tikus wistar. Jenis penelitian yang digunakan yaitu penelitian eksperimental laboratoris dengan rancangan posttest only control group design. Sampel 12 tikus wistar jantan yang dipilih berdasarkan kriteria inklusi dan eksklusi. Dibagi menjadi 3 kelompok: kelompok kontrol (Kk), kelompok perlakuan 1 (Kp1), dan kelompok perlakuan 2 (Kp2). Pajanan radiasi menggunakan unit radiografi periapikal dengan dosis 1,54 mGy. Pencabutan dilakukan pada gigi molar satu kiri rahang bawah. Pemeriksaan jumlah fibroblas dilakukan pada hari ke-3 menggunakan mikroskop binokuler dengan perbesaran 400x. Hasil penelitian menunjukkan nilai rata rata tertinggi adalah Kk (351) dan terendah Kp2 (197). Analisis statistik dengan uji One-Way Annova dan LSD terdapat perbedaan yang bermakna antar kelompok perlakuan (α <0,05). Kesimpulan: Terdapat pengaruh pajanan radiasi sinar x dari radiografi periapikal terhadap penurunan jumlah fibroblas.
COUNT OF LEUKOCYTE AFTER EXPOSURE TO LOW DOSE X RAY RADIATION IN MALE WISTAR RATS (RATTUS NORVEGICUS) Afifah Rizki Fauziah; Swasthi Prasetyarini; Supriyadi Supriyadi
UNEJ e-Proceeding 2022: E-Prosiding Kolokium Hasil Penelitian dan Pengabdian kepada Masyarakat
Publisher : UPT Penerbitan Universitas Jember

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Abstract

Panoramic radiography was one of radiographic examinations in dental practice due to several advantages, which one was for orthodontic treatment. The use of X-ray radiation has biological effects that caused cell death (necrosis or apoptosis). Examination the number of leukocytes can be used as an indicator to determine the responsiveness of white blood cells in preventing the presence of disease and inflammation agents. This research aims to determine the number of leukocytes after low-dose X-ray radiation exposure in male wistar rats (Rattus norvegicus). The methods used experimental laboratory research methods with post test only control group design. A sample of 20 wistar rats were divided into 5 groups: 1 control group and 4 treatment groups that were selected based on inclusion and exclusion criteria. The selected sample was then taken a blood sample before and after low-dose X-ray radiation exposure. Data from the study were conducted parametric statistical tests of One Way Annova and LSD. Radiation exposure used panoramic radiography units under the brand F1-04300 TUUSULA with exposure time 14.1 seconds, and a dose of 10.6 mGy. Examination of the number of leukocytes used the manual method. Data were analyzed using the One Way Anova test with a significant level of α (0.05). Results: The results of the analysis showed that there were significant differences between the control group and the treatment group (α <0.05). Conclusion: There was a change in the number of leukocytes after low-dose X-ray radiation exposure.
Kualitas Visual Radiograf Periapikal Konvensional Setelah Penyimpanan di Ruang Arsip Rekam Medis RSGM Universitas Jember Swasthi Prasetyarini; Gilbert Edgar Nurandhito; Peni Pujiastuti
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 20 No 1 (2023)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v20i1.38603

Abstract

Radiologic supportive examinations are still the primary choice in helping dentists establish a diagnosis and treatment plan. Radiography is the basis of diagnostic imaging in dentistry because the main focus in this field is the hard tissue of the teeth and the bone supporting the teeth. Dental radiographic examination is an examination that supports the establishment of diagnosis, making prognosis, treatment planning, and to evaluate the results of treatment that has been carried out on patients in the field of dentistry. To determine the decline in the visual quality of conventional periapical radiographs of dentistry through the indicator of the onset of brown spots after storage for 21 months in the Medical Record Archive Room of RSGM University of Jember. This study was conducted on 75 conventional periapical radiographs as samples stored in the Medical Record Archive Room of RSGM University of Jember with a temperature of 22°C-28°C using Air Conditioner for 24 hours, illuminated with 40 W lamp, and room humidity conditions of 40%-50%. The research data were analyzed using descriptive analysis. This study shows that the storage duration of conventional periapical radiographs affects the quality of the radiographs. There is a decrease in the visual quality of conventional periapical radiographs through the indicator of brown spots after 21 months of storage in the Medical Records Archive Room of RSGM University of Jember and there is a decrease in the visual quality of radiographs according to the increase in radiograph storage time.
The Effect of Rambutan Leaves (Nephelium lappaceum Linn) Extract on Tail Bleeding Time in Mice Strain Balb-C Budi Yuwono; Ratna Indah Cahyani; Swasthi Prasetyarini; Sulistiyani Sulistiyani; Dyah Setyorini
Health Notions Vol 7, No 3 (2023): March
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn70305

Abstract

Introduction: The most common post-odontectomy bleeding complications were bleeding cases on the first day with a prevalence of 96.6%. Complications of post-odontectomy bleeding if it lasts a long time and is not treated immediately can cause hypovolemic shock, fainting, and further can cause death. Rambutan leaves (Nephelium lappaceum Linn) have several active compounds of tannins, flavonoids, and saponins which have properties to help the hemostatic process by shortening bleeding time. Aims: To examine the effect of rambutan leaves extract (Nephelium lappaceum Linn) on tail bleeding time in balb-C strain mice. Methods: Twelve mice were randomly selected and divided into three groups accordingly; group K- (distilled water), group K+ (tranexamic acid 0.065 mg/g BW), and group P (rambutan leaves extract 260 mg/kg BW). After 60 minutes, the tails of mice were cut along 0.5 cm from the tip of the tail. Bleeding time was observed by turning on the stopwatch along with cutting the tail of the mice and turning it off after the bleeding stopped. Results: Rambutan leaves extract (Nephelium lappaceum Linn) intake at a dose of 260 mg/kg BW had a significant effect (p=0.021) on tail bleeding time, which was to shorten the bleeding time of cutting the tails of mice with Balb-C strain. Conclusions: Based on the results of the study, it can be concluded that rambutan leaves extract (Nephelium lappaceum Linn) has a significant effect on tail bleeding time, which can shorten the bleeding time of cutting the tail of mice with balb-C strain. Keywords: post odontectomy bleeding complications, bleeding time, rambutan leaves extract
Co-Authors Afifah Rizki Fauziah Amandia Dewi Permana Shita Budi Yuwono Budi Yuwono Dyah Setyorini Fitria Nurhabiba Agustine Ghina Lady Salsabila Gilbert Edgar Nurandhito Nungky Tias Susanti Peni Pujiastuti Ratna Indah Cahyani Rizky Purboningtyas Sulistiyani Sulistiyani Supriyadi Supriyadi Zahreni Hamzah