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All Journal Jurnal Farmasi Sains dan Komunitas INDRA: Jurnal Pengabdian kepada Masyarakat
Iman Surya Pratama
Mataram University
Health Professions Medicine & Pharmacology

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ANTI-DIARRHEAL ACTIVITY OF AQUEOUS EXTRACT OF NAGASARI FLOWERS (Mesua ferrea L.) IN BALB/c MICE INDUCED BY Escherichia coli Putu Monik Ananta Puspitarini; Iman Surya Pratama; Bambang Fajar Suryadi
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 16, No 2 (2019)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (590.654 KB) | DOI: 10.24071/jpsc.001814

Abstract

Nagasari (Mesua ferrea L.) is empirically used for curing diarrhea in Nusa Tenggara Barat Province. However, the safety and efficacy of nagasari have not been scientifically validated in animal model. This study evaluates the activity of nagasari flowers aqueous extract in BALB/c mice induced by Escherichia coli to determine the most effective dosage for anti-diarrheal effect. The aqueous extract of nagasari flowers ((0.4% (w/v), 0.8% (w/v), and 1.6% (w/v)) was given to 3 groups of mice whereas negative and positive control groups received aquadestilate and ciprofloxacin 130 mg/kgBW respectively orally once per day for 3 days. The frequency and consistency of feces were observed then the total colony of E. coli in feces was calculated using colony counter. Aqueous extract of nagasari flowers at concentration of 1.6% showed significant inhibitory activity against Escherichia coli compared to positive controls (diarrhea index of 0.425; p0.05 and total colony of E. coli in feces of 100.2; p0.05). This study provides scientific support for the traditional use of aqueous extract of nagasari flowers for the treatment of diarrheal diseases.
Pengembangan media edukasi diabetes mellitus untuk tenaga kefarmasian di puskesmas wilayah Mataram Ni Made Amelia Ratnata Dewi; Iman Surya Pratama; Candra Dwipayana Hamdin
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 2 No. 1 (2021): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.475 KB) | DOI: 10.29303/indra.v2i1.89

Abstract

Adherence in using drugs is one of the factors that determine the success of therapy, especially for chronic diseases such as diabetes mellitus. Efforts that can be made by health workers in increasing adherence to diabetes mellitus sufferers in undergoing treatment are to pay attention to providing information and education to patients. The purpose of this community service activity is to develop educational media for type II diabetes mellitus for pharmaceutical workers in the Mataram regional health center. Making diabetes education media is done by making a pocket book which aims to make it easier for health workers to carry out counseling related to diabetes mellitus and its treatment.
Co-Authors Candra Dwipayana Hamdin Ni Made Amelia Ratnata Dewi Putu Monik Ananta Puspitarini Suryadi, Bambang Fajar