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All Journal journal of internal medicine Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Heart Science Journal
Ari Baskoro
Department Of Internal Medicine, Faculty Of Medicine, Universitas Airlangga – Dr. Soetomo General Hospital, Surabaya
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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ASOSIASI ANTARA POLUSI UDARA DENGAN IgE TOTAL SERUM DAN TES FAAL PARU PADA POLISI LALU LINTAS Fahimi, Mukti; Dharma S, Bayu; Fetarayani, Deasy; Baskoro, Ari; Soegiarto, Gatot; Effendi, Chairul
journal of internal medicine Vol. 13, No. 1 Januari 2012
Publisher : journal of internal medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.192 KB)

Abstract

Ambient air pollution often associated with allergic diseases and impaired respiratory function. Total serum IgE levels was  one  of  the  diagnostic  tools  to  establish  an  allergic  diseases while  lung  function  test was  standard  examination to establish alteration in lung function. Trafc police ofcers were often assigned on the highway is one of the mostvulnerable population against exposure to air pollution. Aim of this study isto know the association between air pollution on total serum IgE levels and lung function in trafc police ofcers compared to staff police ofcer as control.This is anobservational analysis study with cross sectional design.There were 60 police ofcers as a subject, divided in two groups.Thirty subjects as exposured groups and 30 subjects as control group. Air pollution was measured by Pollutant StandardIndex (PSI)/ Indeks Standar Pencemar Udara (ISPU) method. Independent  t-test and Mann-Whitney  test were used  to analyze differences between variabel. Spearman test was used to analyze correlation and strength between variabel.There were no signicant differences in total IgE serum levels between groups (p = 0.301). There were signicant differencesin FEV1 (%p) (p = 0.015), FVC (%p) (p = 0.000) and spyrometry result (p = 0.001). There was no signicant differencein FEV1/FVC ratio (p = 0.573). There were negative weak association between air polution and FEV1 (%p) (r = -0.298;p=0.021) and between air pollution and spyrometry result (r = -0.380; p = 0.003). There was negative moderate associationbetween air pollution and FVC (%p) (r = -0.409; p = 0.001). There was no association between air pollution and FEV1/FVC ratio (r = 0.058; p = 0.662). There was signicant association between air pollution and impaired respiratory functionbut there was no association between air pollution and total serum IgE levels.
Correlation between Allergic Rhinitis and Rhinosinusitis in ENT Outpatient Clinic Patients Felicia Alvita Tjahjono; Irwan Kristyono; Ari Baskoro
Biomolecular and Health Science Journal Vol. 3 No. 1 (2020): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v3i1.19127

Abstract

Introduction: Rhinosinusitis and allergic rhinitis are common health problems. Allergic rhinitis patients tend to have edema on their nasal mucosa, disrupted cilia, and excessive secrete production that clogged paranasal sinuses’ ostiums and lead to inflammation and infection of the paranasal sinuses. There is still a contradiction of allergic rhinitis as predisposing factor of rhinosinusitis. Those correlation is not yet clear, thus we aim to analyze the correlation between allergic rhinitis and rhinosinusitis.Methods: This study was a cross-sectional design. The samples were obtained by consecutive sampling. Adult patients above 19 years old with nasal discharge were examined by the doctors on duty and interviewed. Medical data obtained was recorded and analyzed using chi square test.Results: From 98 patients, 17 patients (17.35%) had both rhinosinusitis and allergic rhinitis, 48 patients (48.98%) only had rhinosinusitis, and 13 patients (13.26%) only had allergic rhinitis. Patients who had neither rhinosinusitis nor allergic rhinitis reported to be 20 patients (20.41%). Chi square test showed that allergic rhinitis had no significant correlation with rhinosinusitis (p=0.266).Conclusion: There is no significant correlation between allergic rhinitis and rhinosinusitis. Rhinosinusitis is a multifactorial disease.
Profile of Anaphylactic Reaction in Surabaya from January 2014 to May 2018 Amalia Putri Uswatun Hasanah; Ari Baskoro; Pesta Parulian Maurid Edwar
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 11 No. 2 (2020): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V11I22020.61-64

Abstract

Introduction: Anaphylactic reaction is systemic hypersensitivity reaction. It is type 1 hypersensitivity reaction. The incidence can be mild to severe due to the sudden release of mediators by effector cells. This research aimed to examine the prevalence of anaphylactic reaction in Dr. Soetomo General Hospital in January 2014 until May 2018.Methods: This study was a cross-sectional and retrospective study by assessing patients’ medical records and was analyzed descriptively.Results: 22 patients were identified as anaphylactic reaction. The prevalence of anaphylactic reaction from year to year cannot be identified surely because of underdiagnose and underreporting. The most common cause of anaphylactic reaction in Dr. Soetomo General Hsopital was drugs (50%). The most drugs were antibiotics (22.73%) and the most antibiotics were groups of penicillin (40%) and cephalosporin (40%). The most common clinical manifestation was skin-related (77.27%), which includes urticaria (4.55%), angioedem (27.27%), pruritus (27.27%) cold skin (0.09%), pallor (4.55%), and cyanosis (4.55%). Most patients became better (45.54%) after getting treatment from the doctor.Conclusion: The most common cause of anaphylactic reaction was drugs, the most drugs were antibiotics and the most antibiotics were groups of penicillin and cephalosporin. The most clinical manifestation was skin-related. Most of anaphylactic reaction’s patients became better after getting treatment from the doctor. Underdiagnose and underreporting are the problem often encountered in cases of anaphylactic reaction. 
Evaluating the connection between mean platelet volume (MPV) and peripheral arterial disease risk: A meta-analysis Dharmawan, Andronikus; Baskoro, Ari
Heart Science Journal Vol. 5 No. 4 (2024): The Current Perspective About Cardiometabolic Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2024.005.04.7

Abstract

BACKGROUND: Numerous studies have been conducted to evaluate the role of Mean Platelet Volume (MPV) in relation to Peripheral Artery Disease (PAD). However, the results of these studies have been inconsistent regarding the significance of MPV as an indicator for PAD.OBJECTIVE: This meta-analysis aimed to clarify the role of MPV in PAD by collecting and analyzing data from various studies. The goal was to provide a more definitive assessment of whether MPV levels could serve as a reliable indicator for PAD.METHODS: We conducted a meta-analysis from July to August 2024, utilizing data from three major databases: Scopus, Embase, and PubMed. We gathered data on MPV levels from studies comparing PAD patients with control groups. The meta-analysis included cumulative effect estimates, with analysis performed using the inverse variance method to synthesize data and evaluate the overall effect of MPV on PAD.RESULTS: Nine studies were included in this meta-analysis, comprising 1,214 PAD cases and 6,568 controls. Our analysis demonstrated that MPV was a significant marker in PAD, with PAD patients having higher MPV levels compared to controls (MD: 0.46; 95%CI: 0.25, 0.66; p Egger: 0.0911; p Heterogeneity <0.0001; p <0.0001).CONCLUSION: Our findings support that MPV is an important indicator in the context of PAD. Further study is needed to explore the clinical applications of MPV in PAD and to establish standardized thresholds for its use in clinical practice.
Co-Authors Amalia Putri Uswatun Hasanah Bayu Dharma S Chairul Effendi Deasy Fetarayani Dharmawan, Andronikus Edwar, Pesta Parulian Maurid Felicia Alvita Tjahjono Gatot Soegiarto Mukti Fahimi