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HUBUNGAN KUALITAS HIDUP PASIEN DIABETES MELITUS TIPE 2 DENGAN KEPATUHAN MINUM OBAT DI RSUD ULIN BANJARMASIN Lutfianada Hasanah; Herda Ariyani; Dedi Hartanto
JCPS (Journal of Current Pharmaceutical Sciences) Vol 6 No 1 (2022): September
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

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Abstract

Penyakit diabetes melitus (DM) tipe 2 menjadi penyebab hingga 70-80% resiko komplikasi dan kematian jika tidak ditangani dengan baik. Keberhasilan suatu pengobatan sangat dipengaruhi oleh kepatuhan penderita DM. Salah satu faktor kegagalan kontrol glukosa darah pasien DM adalah ketidakpatuhan yang dapat berdampak pada kompikasi penyakit ini dan bisa berujung pada kematian. Penelitian ini bertujuan untuk mengetahui kualitas hidup dan kepatuhan, serta hubungan kualitas hidup dan kepatuhan minum obat pasien DM tipe 2 di RSUD Ulin Banjarmasin. Rancangan penelitian yang digunakan adalah cross sectional. Penelitian ini dilakukan pada tanggal 18 Mei 2022-18 Juni 2022. Teknik pengambilan sampel menggunakan total sampling dengan jumlah sampel yang diambil sebesar 48 orang. Instrumen yang digunakan adalah kuesioner ARMS dan EQ-5D. Analisis data bivariat menggunakan uji fisher exact. Hasil penelitian mayoritas kualitas hidup pasien DM tipe 2 dalam kategori ada beberapa masalah sebesar 44 orang (91,7%), sedangkan tingkat kepatuhan pasien dalam kategori sedang sebesar 46 orang (95,8%). Analisis statistik menunjukkan ada hubungan antara kepatuhan dengan kualitas hidup (p-value = 0,005)
EFEKTIVITAS INFUSA JAHE MERAH (ZINGIBER OFFICINALE VAR. RUBRUM) SEBAGAI ANTIDIARE PADA MENCIT PUTIH JANTAN YANG DI INDUKSI OLEUM RICINI DENGAN METODE TRANSIT INTESTINAL Yulis Azizah; Rizka Mulya Miranti; Dedi Hartanto; Retna Eka Dewi
Journal of Innovation Research and Knowledge Vol. 3 No. 3: Agustus 2023
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jirk.v3i3.6348

Abstract

Red ginger is a plant of the Zingiberaceae family which contains active compounds which are consider to have a major contribution to the anti-diarrheal effect are steroids, tannins, flavonoids, and saponins. The purpose of this study was to determine if red ginger infusion has an antidiarrheal effect and what is the effective dose if it has an anti- diarrheal effect. This research is an experimental with a Completely Randomised plan (CRP) with a one way model. Twenty-four mice were randomly assigned to 6 groups of 4 mice within each group. The Red ginger infusion was tested with 3 different dosage variations; 1.047 g/kgBW, 2.095 g/kgBW, and 4.19 g/kgBW. The Antidiarrheal activity in this study was determined by computing the ratio of the bowel length passed through the marker to total length of the intestine. The results showed that red ginger infusion has an anti-diarrheal effect. Infusion of red ginger at doses of 1.047 g/kg BB, 2.095 g/kg BB and 4.19 g/kgBW, resulting in average ratios of 0.596, 0.37975 and 0.164125, consecutively. Based on a statiscal data analysis with the Mann Whitney Test, it was obtained that the ratio between a dose of 4.19 g / kgBW and the Loperamide comparison group of 4 mg / kgBW dose did not have a meaningful difference. So the most effective dose of red ginger infusion as an anti-diarrhea is 4.19 g/kgBW.
ANALISIS EFEKTIVITAS BIAYA TERAPI GAGAL JANTUNG KONGESTIF PADA PASIEN RAWAT INAP DI RSUD MUARA TEWEH PERIODE JULI-NOVEMBER 2021 Dedi Hartanto; Anida Anida; Retna Eka Dewi
Jurnal Komunitas Farmasi Nasional Vol. 2 No. 1 (2022): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

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Abstract

Cost-Effectiveness Analysis (CEA) is a method in pharmacoeconomics used to analyze a therapy that is clinical and cost. The purpose of this study was to determine the direct medical costs and to find out which cost-effective therapy for patients with Congestive Heart Failure (CHF) was used in RSUD Muara Teweh for the period July-November 2021. This study was an analytical observational study by taking secondary data. Retrospectively from medical records, details of financial costs, and details of medical costs. The data collection technique used is a total sampling technique. There are 26 people who meet the inclusion criteria and exclusion criteria from a total population of 42 people. The data from this study were grouped based on the class of CHF drug therapy. The results of this study showed that the Diuretic groups were the most effective therapy in reducing blood pressure in CHF patients with effectiveness value of 0,58. The most cost-effective drug class based on the ACER value is ACE-I with the smallest ACER value of Rp. 3.670.770.