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All Journal Journal of Medical Physics and Biophysics Jurnal Spektra Jurnal Penelitian Sains Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Spektra: Jurnal Fisika dan Aplikasinya PROSIDING SEMINAR NASIONAL FISIKA (E-JOURNAL) Indonesian Journal of Cancer
Supriyanto Ardjo Pawiro
University Of Indonesia
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Chemistry Electrical & Electronics Engineering Energy Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Other

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ESTIMASI DOSIS RADIASI PADA PERLAKUAN CONE BEAM CT RADIOTERAPI Priska Andini Putri; Rina Taurisia; Supriyanto Ardjo Pawiro
PROSIDING SEMINAR NASIONAL FISIKA (E-JOURNAL) Vol 3 (2014): PROSIDING SEMINAR NASIONAL FISIKA (E-JOURNAL) SNF2014
Publisher : Program Studi Pendidikan Fisika dan Program Studi Fisika Universitas Negeri Jakarta, LPPM Universitas Negeri Jakarta, HFI Jakarta, HFI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (519.326 KB)

Abstract

Cone Beam CT adalah perangkat citra pemandu yang diintegrasikan pada perangkat LINAC radioterapi. Perangkat tersebut banyak digunakan untuk verikasi posisi pasien dalam tindakan radioterapi. Dalam penelitian ini telah dilakukan untuk estimasi dosis pada daerah kepala, dada, dan pelvis dengan menggunakan perlakuan Cone Beam CT satu putaran penuh. Fantom rando digunakan pada penelitian ini untuk mensimulasikan keadaan yang mendekati sebenarnya dengan kondisi klinis 100 kVp 145 mAs, 110 kVp 262 mAs, dan 125 kVp 680 mAs untuk berturut-turut prosedur perlakuan CBCT kepala, dada, dan pelvis. Dosimeter yang digunakan dalam penelitian ini adalah TLD yang dikalibrasi di PTKMR BATAN dengan kondisi yang sesuai dengan kondisi klinisnya. Hasil yang diperoleh dari penelitian ini adalah 4.018±0.334 mGy, 4.210±0.428 mGy, dan 12.547±3.046 mGy berturut-turut pada kepala, dada, dan pelvis. Keywords: dose, CBCT, TLD, Rando phantom.
THE COMPARISON OF 2D DOSE PATIENT-SPECIFIC QUALITY ASSURANCE BETWEEN MONTE CARLO-CONVOLUTION AND MODIFIED CLARKSON INTEGRATION ALGORITHM Azzi, Akbar; Pawiro, Supriyanto Ardjo; Mart, Terry
Spektra: Jurnal Fisika dan Aplikasinya Vol. 8 No. 2 (2023): SPEKTRA: Jurnal Fisika dan Aplikasinya, Volume 8 Issue 2, August 2023
Publisher : Program Studi Fisika Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/SPEKTRA.082.01

Abstract

A sophisticated machine of radiotherapy treatment process follows the complexity of the quality assurance (QA) measurement. Non-measurement QA becomes one of the solutions to reduce the medical physicists’ workload. However, this method has not been clinically established. This study compared two non-measurement methods of patient-specific quality assurance (PSQA) to find the feasible algorithm for the adaptive radiotherapy process. Monte Carlo-based (MC) PSQA used a phase space file of the medical linear accelerator (Linac) to obtain the photon energy fluence and forward projected to the isoplane. In contrast, Modified Clarkson Integration-based (MCI) used a non-uniform fluence map in the isoplane. For the modulated intensity, we used a pair of the dynamic log files of the multileaf-collimator (MLC) and then employed them in the algorithms. The dose distributions of MC and MCI methods were compared to the treatment planning system (TPS) using gamma index analysis. We found that the gamma pass rates (GPR) for MC-TPS and MCI-TPS were 99.54% and 99.57%, respectively. Further, the dose distribution in the off-axis region for the MCI method showed lesser accuracy due to the higher secondary dose contribution. The linac log file information can be used and calculated into a 2D dose distribution using both MC and MCI methods, providing high-accuracy results.
EVALUATING RENAL TIME-INTEGRATED ACTIVITY COEFFICIENT IN [177Lu]Lu-DOTA-TATE THERAPY: SIMULTANEOUS VS. SEPARATE KIDNEY MODELING USING NON-LINEAR MIXED-EFFECTS MODELING Indra Budiansah; Assyifa Rahman Hakim; Fira Dwi Ananda; Supriyanto Ardjo Pawiro; Deni Hardiansyah
Joint Prosiding IPS dan Seminar Nasional Fisika Vol. 14 No. 1 (2026): Joint Prosiding IPS dan Seminar Nasional Fisika
Publisher : Program Studi Pendidikan Fisika dan Program Studi Fisika Universitas Negeri Jakarta, LPPM Universitas Negeri Jakarta, HFI Jakarta, HFI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/03.1401.FA01

Abstract

This study aimed to compare renal time-integrated activity coefficients (TIACs) in [177Lu]Lu-DOTA- TATE therapy using non-linear mixed-effects modeling (NLMEM), by evaluating the effect of the fitting setting method of left and right kidney biokinetic data to TIAC calculation. Renal biokinetic data of [177Lu]Lu-DOTA-TATE were collected from ten patients with neuroendocrine tumors from literature (PMID:33443063). SPECT/CT imaging was performed between days 1 and 7 after-injection. The bi-exponential function parameters were fitted to biokinetic data using NLMEM performed using NONMEM software, with two fitting approaches: simultaneous fitting of both kidneys and separate fitting of the left and right kidneys. TIACs from the simultaneous fitting were defined as simultaneous TIACs (siTIACs), and those from separate fitting as separated TIACs (seTIACs). The differences between siTIACs and seTIACs were assessed using relative deviations (RDs), with seTIACs considered equivalent to siTIACs if RD was below 5%. The bi-exponential function successfully describes the renal biokinetic data. seTIACs showed good agreement with the siTIACs, with median[min, max] RD of -1.6[-4.5, 0.8]%. Simultaneous fitting of left and right kidneys biokinetic data using the NLMEM approaches produced similar TIACs to those obtained from separate fittings. Therefore, TIACs from simultaneous and separate fittings of renal biokinetic data are comparable and clinically applicable.
Dosimetry Audit of IMRT and VMAT External Radiotherapy Techniques: Multi-Institutional Study in East Java Province Maqsuroh, Fiki Hurum; Zahro, Ummu Mar’atu; Dzulfikar, Ahmad Zaki; Harfiyyah, Vivin Fashihatil; Hentihu, Fatimah Kunti; Pawiro, Supriyanto Ardjo
Indonesian Journal of Cancer Vol 19, No 4 (2025): December
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i4.1258

Abstract

Background: The Multi-Leaf Collimator (MLC) application is utilized in the Linear Accelerator (LINAC) with Intensity Modulated Radiotherapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT) methods, both of which include advanced methods of administering radiotherapy, which aim to improve dose distribution and increase local tumour control by adjusting the external beam into a shape-specific tumour. Dosimetry audit is a crucial quality assurance procedure in radiotherapy facilities, ensuring patient dosing quality. This study aimed to simulate the dosimetry audit method of IMRT techniques and VMAT with point dose and dose delivery distribution evaluation. Method: The phantom utilized in this study was constructed from acrylic material and featured a C-shaped insert. It comprised a main body and an insert, with the body measuring 15 × 15 × 15 cm and the insert measuring 6 × 6 × 6 cm. The main body was fabricated from polymethyl methacrylate (PMMA) with a density of 1.17 g/cm³, serving as a surrogate for human tissue. The insert, composed of a resin and carbon powder mixture with a density of 1.19 g/cm³, was designed to represent both the organ at risk (OAR) and the planning target volume (PTV) in the study. Phantom images were taken with the center of the CT simulator, then radiation planning was performed with a PTV dose of 4 Gy/2 fractions (D95% 95%, D2% 107%, and Dmax 110%) and a maximum OAR dose of 2.8 Gy. This study was conducted at four radiotherapy centres in East Java province by conducting dosimetry audits on point doses using TLD and dose distribution by evaluating gamma index analysis using EBT3 Film.Results: The results of point dose readings using TLD at all centres and radiation techniques were still within the tolerance limit, namely ± 5%. Apart from that, to evaluate the gamma index using film, at three centres with the 3%/3mm criteria, the gamma passing rate was 90%. Conclusion: This method can be used as a reference in conducting dosimetry audits in radiotherapy using TLD and film
english english Syarifatul Ulya; Dea Ryangga; Wahyu Edy Wibowo; Nuruddin Nasution; Supriyanto Ardjo Pawiro
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 17 No 1 (2023): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v17i1.5848

Abstract

Regarding the increasing use of small-field photons in clinical treatment, in this study, we investigate the use of small-field electron beams in clinical treatment. This study aimed to evaluate small-field electron beam dosimetry of the nasopharyngeal, thyroid, and ethmoid sinus carcinoma cases. Dose measurement was done using EBT3 film. In nasopharyngeal cases with a homogenous area and irregular surface, the dose discrepancies for 6 MeV energy were unpredictable except for the 5×5 cm2 field size. For all energies in 5×5 cm2 field size, the dose discrepancies were less than 3%. In these cases, we found that a smaller electron beam field will increase the percentage of the dose discrepancy. This is caused by the effect of the lateral scatter disequilibrium in a small field electron beam. For ethmoid sinus cases, dose discrepancy depends on the field size and inhomogeneity of bone and tissue organ. Based on the evaluation of doses on the spinal cord, chiasm, and larynx (OAR), it can be seen that these organs received a very small dose. From this result, a small field electron beam is recommended for cases with a homogeneous target. However, in cases with a heterogenous target, further investigation is needed.
Co-Authors Ahmad Syafi'i Ahmad Zaki Dzulfikar, Ahmad Zaki Andrian Dede Handika Annisa Rahma Fauzia Ari Surya Miharja, Ari Assyifa Rahman Hakim Azzi, Akbar Cahya Wulandari Deni Hardiansyah Djarwani S. Soejoko Elsa Angelina Endang Nurtriningsih Erlin Ingrina Fajar Haristyo Fatimah Kunti Hentihu, Fatimah Kunti Fira Dwi Ananda Harfiyyah, Vivin Fashihatil Indra Budiansah Khaerul Mar'ie Kristina Tri Wigati Laras Ati Nur Fatimah Maqsuroh, Fiki Hurum Nurdina Gita Pratiwi Nuruddin Nasution Nuruddin Nuruddin Petrananda Dea Karunia Priska Andini Putri Putri Amalia Pontoh Riana Dian Pertiwi Rina Taurisia Ryangga, Dea Sonak Tioria Tarigan Suwandi Suwandi Syarifatul Ulya Syarifatul Ulya Syarifatul Ulya Terry Mart Wahyu Edy Wibowo Wahyu Edy Wibowo Wahyu Edy Wibowo Wahyu Edy Wibowo Wahyu Edy Wibowo Yosi Sudarsi Asril Yosi Sudarsi Asril Yurneli Luthan Zahro, Ummu Mar’atu