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All Journal Physics Student Journal Indonesian Physical Review Indonesian Journal of Cancer
Fatimah Kunti Hentihu, Fatimah Kunti
Brawijaya University
Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Medicine & Pharmacology Physics Public Health

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Perkiraan Dosis Ekuivalen Neutron Termal pada Pasien Radioterapi Linac 15 MV Hentihu, Fatimah Kunti; Noor, Johan A. E.; -, Bunawas
Physics Student Journal Vol 2, No 1 (2014)
Publisher : Department of Physics - Faculty of Science

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Abstract

Penggunaan linac dengan energi foton lebih dari 10 MV akan menghasilkan neutron dari reaksi fotoneutron antara foton yang dihasilkan dengan bahan-bahan di sekitar kepala linac. Kami telah melakukan penelitian dengan menggunakan pesawat  linac 15 MV untuk mengukur dosis ekuivalen neutron termal di dalam tubuh dengan menggunakan sebuah fantom atropomorfik berbahan polietilen yang disisipi detektor CR-39 beradiator BN-1. Ketika neutron cepat masuk ke dalam fantom dan berinteraksi, neutron cepat akan mengalami moderasi dan termalisasi menjadi neutron termal. Neutron termal tersebut dideteksi dengan detektor CR-39 beradiator BN-1 karena reaksi antara neutron termal dengan boron menghasilkan partikel alfa yang akan berinteraksi dengan detektor CR-39 dan menghasilkan jejak. Sebelum digunakan, detektor dikalibrasi terlebih dahulu dengan sumber neutron 252Cf  untuk memperoleh persamaan kalibrasi    y = 164x. Sensitivitas detektor CR-39 pada penelitian ini sebesar 164 jejak/cm2.µSv. Dosis ekuivalen neutron termal dari penyinaran linac dengan dosis terapi 2 Gy dan 3 Gy sebesar 52 - 206 µSv dengan ketidakpastian ±5% dan 78-309 µSv dengan ketidakpastian ±4%. Variasi dosis tersebut berhubungan dengan letak titik (kedalaman dan jarak dari isosenter penyinaran) dan jenis bahan pada fantom.
DOSIMETRIC EVALUATION OF POST-MASTECTOMY THREE-DIMENSIONAL CONFORMAL RADIATION THERAPY (3DCRT) BREAST CANCER TREATMENT PLANS Herwiningsih, Sri; Naba, Agus; Rianto, Sugeng; Hentihu, Fatimah Kunti
Indonesian Physical Review Vol. 6 No. 3 (2023)
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/ipr.v6i3.240

Abstract

Breast cancer is the most diagnosed cancer in women globally. External beam radiotherapy is one method to treat breast cancer, which can be given to the patients after mastectomy. The changes in anatomy of breast tissues after mastectomy makes the radiotherapy treatment very challenging to ensure the prescribed dose delivered to the tumour target while the radiation to the surrounding critical organs is kept to be low. This study aims to evaluate the dosimetric parameters of radiotherapy treatment plans for breast cancer patients after mastectomy delivered using 3DCRT technique. The evaluation includes the target coverage to the PTV, defined as the volume of PTV receiving 95% of the prescribed dose and the volume of PTV receiving 107% of the prescribed dose. The min, max and mean dose to the PTV were also recorded. The dosimetric parameters to the OARs were Dmean and V20 to the lung, Dmean and V25 to the heart, Dmean to esophagus and Dmax to the spinal cord. The result shows that target coverage is fulfilled in most of the plans, however the host spot in the PTV also observed in the most of the plans. Dose to heart, left lung, esophagus and spinal cord are relatively low and below the constraint recommended by QUANTEC, however the V20 to the right lung exceeded the constraint in the most of the plans. The combination of photon and electron beam might be useful to reduce the excessive dose to the right lung.
Dosimetry Audit of IMRT and VMAT External Radiotherapy Techniques: Multi-Institutional Study in East Java Province Maqsuroh, Fiki Hurum; Zahro, Ummu Mar’atu; Dzulfikar, Ahmad Zaki; Harfiyyah, Vivin Fashihatil; Hentihu, Fatimah Kunti; Pawiro, Supriyanto Ardjo
Indonesian Journal of Cancer Vol 19, No 4 (2025): December
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i4.1258

Abstract

Background: The Multi-Leaf Collimator (MLC) application is utilized in the Linear Accelerator (LINAC) with Intensity Modulated Radiotherapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT) methods, both of which include advanced methods of administering radiotherapy, which aim to improve dose distribution and increase local tumour control by adjusting the external beam into a shape-specific tumour. Dosimetry audit is a crucial quality assurance procedure in radiotherapy facilities, ensuring patient dosing quality. This study aimed to simulate the dosimetry audit method of IMRT techniques and VMAT with point dose and dose delivery distribution evaluation. Method: The phantom utilized in this study was constructed from acrylic material and featured a C-shaped insert. It comprised a main body and an insert, with the body measuring 15 × 15 × 15 cm and the insert measuring 6 × 6 × 6 cm. The main body was fabricated from polymethyl methacrylate (PMMA) with a density of 1.17 g/cm³, serving as a surrogate for human tissue. The insert, composed of a resin and carbon powder mixture with a density of 1.19 g/cm³, was designed to represent both the organ at risk (OAR) and the planning target volume (PTV) in the study. Phantom images were taken with the center of the CT simulator, then radiation planning was performed with a PTV dose of 4 Gy/2 fractions (D95% 95%, D2% 107%, and Dmax 110%) and a maximum OAR dose of 2.8 Gy. This study was conducted at four radiotherapy centres in East Java province by conducting dosimetry audits on point doses using TLD and dose distribution by evaluating gamma index analysis using EBT3 Film.Results: The results of point dose readings using TLD at all centres and radiation techniques were still within the tolerance limit, namely ± 5%. Apart from that, to evaluate the gamma index using film, at three centres with the 3%/3mm criteria, the gamma passing rate was 90%. Conclusion: This method can be used as a reference in conducting dosimetry audits in radiotherapy using TLD and film
Co-Authors Agus Naba Ahmad Zaki Dzulfikar, Ahmad Zaki Bunawas - Harfiyyah, Vivin Fashihatil Johan A. E. Noor Maqsuroh, Fiki Hurum Sri Herwiningsih Sugeng Rianto Supriyanto Ardjo Pawiro Zahro, Ummu Mar’atu