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All Journal Pharmasipha OISAA Journal of Indonesia Emas Jurnal Ilmiah Global Farmasi Jurnal Abdimas Kesehatan
Anggun Mahirotun Nur Sholikhah
Universitas Darussalam Gontor
Humanities Biochemistry, Genetics & Molecular Biology Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences

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Journal : Pharmasipha

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FORMULASI TABLET EFFERVESCENT DAUN KERSEN (Muntingia calabura L.) DENGAN VARIASI KONSENTRASI EFFERVESCENT MIX Fitria Susilowati, Anggun Mahirotun Nur Sholikhah, Surya Amal,
Pharmaceutical Journal of Islamic Pharmacy Vol 2, No 2 (2018)
Publisher : Universitas Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v2i2.2634

Abstract

Muntingia calabura L. is one of the type genus Muntingia which grows ever green and always has a lot of benefits but has not been used optimally. This study aims to utilize Muntingia calabura leaves take one form of pharmaceutical preparations namely effervescent tablet. Effervescent tablets are made using dry granulation of the metanol : water extract Muntingia calabura leaves. This study used variations of the concentration of effervescent mix to know the best concentration of the effervescent mix. Method to make it in relative humidity condition (RH) and appropriate temperature. Three of the formula that has made qualified evaluation of granules (time flow, angle of repose, and compresibility) and evaluation of  effervescent tablets (weight variation, hardness test, time dissolved, assay test water, and pH level test). The results of analysis, showed that the three all formulas meet the requirement of test characteristics of granule and effervescent tablet.  Based on the results of the research can be conclude that the  formula with a concentration of 60% (formulation 2) effervescent mix is the best formula. This is due to the formula for concentration of 60% effervescent mix is the concentration that is ideal concentration for effervescent tablets.
Formulasi Tablet Effervescent Daun Kersen (Muntingia calabura L.) dengan Variasi KonsentrasiEffervescent Mix Anggun Mahirotun Nur Sholikhah; Surya Amal; Fitria Susilowati
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 2, No 2 (2018): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (264.923 KB) | DOI: 10.21111/pharmasipha.v2i2.2779

Abstract

Muntingia calabura L. is one of the type genus Muntingia which grows ever green and always has a lot of benefits but has not been used optimally. This study aims to utilize Muntingia calabura leaves take one form of pharmaceutical preparations namely effervescent tablet. Effervescent tablets are made using dry granulation of the metanol : water extract Muntingia calabura leaves. This study used variations of the concentration of effervescent mix to know the best concentration of the effervescent mix. Method to make it in relative humidity condition (RH) and appropriate temperature. Three of the formula that has made qualified evaluation of granules (time flow, angle of repose, and compresibility) and evaluation of effervescent tablets (weight variation, hardness test, time dissolved, assay test water, and pH level test). The results of analysis, showed that the three all formulas meet the requirement of test characteristics of granule and effervescent tablet. Based on the results of the research can be conclude that the formula with a concentration of 60% (formulation 2) effervescent mix is the best formula. This is due to the formula for concentration of 60% effervescent mix is the concentration that is ideal concentration for effervescent tablets.
Co-Authors Aida, Ayu Choirul Umi Haniyah DR, Juwita Fitria Susilowati Indah Tri Lestari Kurniawan, Kurniawan Raras Dewi, Yulisa Satwika Budi Sawitri Surya Amal