Garuda - Garba Rujukan Digital

Article Per Year (5 Year)

p-Index From 2020 - 2025

0.23

P-Index

This Author published in this journals

All Journal Pharmasipha

Fitria Susilowati

Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Darussalam Gontor

Author-ID : 3438989

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 5 Documents Claim Missing Document

Claim Missing Document

Articles

Formulasi Tablet Effervescent Daun Kersen (Muntingia calabura L.) dengan Variasi KonsentrasiEffervescent Mix Anggun Mahirotun Nur Sholikhah; Surya Amal; Fitria Susilowati
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 2, No 2 (2018): September
Publisher : University Of Darussalam Gontor

Muntingia calabura L. is one of the type genus Muntingia which grows ever green and always has a lot of benefits but has not been used optimally. This study aims to utilize Muntingia calabura leaves take one form of pharmaceutical preparations namely effervescent tablet. Effervescent tablets are made using dry granulation of the metanol : water extract Muntingia calabura leaves. This study used variations of the concentration of effervescent mix to know the best concentration of the effervescent mix. Method to make it in relative humidity condition (RH) and appropriate temperature. Three of the formula that has made qualified evaluation of granules (time flow, angle of repose, and compresibility) and evaluation of effervescent tablets (weight variation, hardness test, time dissolved, assay test water, and pH level test). The results of analysis, showed that the three all formulas meet the requirement of test characteristics of granule and effervescent tablet. Based on the results of the research can be conclude that the formula with a concentration of 60% (formulation 2) effervescent mix is the best formula. This is due to the formula for concentration of 60% effervescent mix is the concentration that is ideal concentration for effervescent tablets.

Pengaruh Jenis Pelarut pada Ekstraksi Daun Kumis Kucing (Orthosiphon stamineus Benth) terhadap Kadar Kalium Janugraheni Prasetya Ningrum; Fitria Susilowati; Lija Oktya Artanti
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 3, No 1 (2019): Maret
Publisher : University Of Darussalam Gontor

Indonesia has a variety of biological resources in various regions. One of the plants that can be used as medicine is Orthosiphon stamineus Benth. Orthosiphon stamineus Benth has several secondary metabolites, one of them is Potassium that has diuretic function. This study aims to know the effect of the solvent type to the level of Pottasium on the extraction of Orthosiphon stamineus Benth. The research method was done using atomic absorption spectrophotometry instrument. Samples were obtained and identified from UPT Materia Medica Batu Malang, East Java, sample was extracted by percolation method and infusion. The sample was the destructed then was destructied using HNO3 to transform organic metal into inorganic, then measured the absorbance using atomic absorption spectrophotometry at wavelength 766,5. The result showed that the concentration of potassium in Orthosiphon stamineus Benth in water solvent, ethanol 70%, ethanol 96%, and methanol were (29,256 ± 1,581) mg/L, (51,294 ± 5,028) mg/L, (31,406 ± 2.777) mg/L, (58.351 ± 2.925) mg/L. The method had in standard deviation value of each solvent is; water solvent 0,005, ethanol 70% 0,017, ethanol 96% 0,009, and methanol 0,001. Based on statistical test calculations using different test calculations over two samples there was a difference in average of Potassium level between each solvent, with the highest Potassium content found in methanol solvent.

UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAN EKSTRAK AIR BIJI HABBATUSSAUDA’ (Nigella sativa) Yulian Catur Rini; Fitria Susilowati; Andi Sri Suriati Amal
Pharmasipha: Pharmaceutical Journal of Islamic Pharmacy Vol 4, No 1 (2020): Maret
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v4i1.3945

Biji Habbatussauda’ (Nigella sativa) diketahui mengandung antioksidan yang dapat mengurangi aktivitas radikal bebas. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan senyawa polar dari ekstrak etanol dan air. Penelitian ini dilakukan dengan membuat ekstrak pelarut etanol 96% dengan metode maserasi dan pelarut air dengan pengeringan ekstrak yang diuapkan dengan freeze dry. Uji fitokimia yang dilakukan meliputi 5 golongan senyawa yaitu terpenoid, saponin, tanin, alkaloid dan flavonoid. Pengujian antioksidan pada keduanya menggunakan kontrol positif berupa asam askorbat (vitamin C) dengan konsentrasi 0,1; 0,2; 0,3; 0,4 dan 0,5 ppm. Blanko yang digunakan dalam penelitian ini adalah DPPH 0,1 mM. Pengujian dilakukan dengan mereaksikan 1 ml sampel dan 1 ml DPPH dengan menggunakan operating time selama 30 menit untuk diukur absorbansinya dengan spektrofotometri UV-Vis pada panjang gelombang 517 nm. Data yang diperoleh dihitung untuk mengetahui nilai IC50 dari masing-masing sampel sehingga diketahui hasil perbandingan dari keduanya. Hasil penelitian menunjukkan bahwa pengujian fitokimia ekstraksi dengan maserasi menggunakan pelarut etanol 96 % dari pengujian fitokimia adalah positif pada terpenoid, saponin, tanin, alkaloid, flavonoid sedang ekstraksi dengan freeze dry menggunakan pelarut air negatif pada terpenoid dan positif pada saponin tanin alkaloid serta flavonoid. Dari penelitian memiliki hasil dimana ekstrak dengan metode maserasi dengan pelarut etanol memiliki nilai IC50 4,402 sedang ekstrak yang diuapkan dengan freeze dry memiliki nilai IC50 4,277. Hingga dapat disimpulkan bahwa ekstrak air memiliki aktivitas antioksidan yang lebih besar dibanding ekstrak etanol yang mana keduanya termasuk ke dalam kategori antioksidan bersifat sangat kuat karena kurang dari 50 ppm.

Variasi Jenis Humektan pada Formulasi Sediaan Masker Gel Peel Off Ekstrak Kulit Buah Pisang Kepok (Musa paradisiaca pericarpium) Frida Ardina Pratiwi; Surya Amal; Fitria Susilowati
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 2, No 2 (2018): September
Publisher : University Of Darussalam Gontor

Peel-off gel mask is one type of facial mask that has advantages in its use that is easily removed or released like an elastic membrane. This study aims to determine the kepok banana peelcan be formulated into a peel-off gel mask and the effect of adding properly humectant so that the product of peel-off gel mask is effective, stable, and safe in its use. The gel mask formulation is made with Polyvinyl Alcohol (PVA) base on 13% concentration. Evaluations of gel mask preparation include observation of changes in color, odor, texture, pH, dry time, dispersion and viscosity for 28 days at 40ºC storage temperature. The result data of peel-off gel mask preparation is analyzed by SPSS 16.0, with one way ANOVA. The results showed that humectant variation significantly affected organoleptic and drying time (p < 0.05) and humectant variation significantly did not affect pH, homogeneity, viscosity and dispersion (p > 0,05). The best formula of the facial mask extract from the Musa paradisiaca pericarpium peel extract in the form of peel off gel based on the organoleptic test and the dry time is the formula three, which is honey as humectant.

Formulasi Tablet Effervescent Ekstrak Kulit Buah Ddelima Putih (Punica granatum var. album) dengan Variasi Asam Sitrat dan Asam Tartrat Rizqi Fajri Ramadhani; Andi Sri Suriati Amal; Fitria Susilowati
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol 2, No 1 (2018): Maret
Publisher : University Of Darussalam Gontor

Allah created all the plants in this world with their own benefits. Pomegranate is one of the plants that has many benefits. One part of the pomegranate that can be utilized to be effervescent tablet is the fruit peel. One of the sources ingredients in the formulation of effervescent tablet is the source of acid. This study aims to find the best formula for effervescent tablets of extract leather White Pomegranate and investigating the effect of variation of citric and tartrate acid to characteristic of granule and tablet. The ratio of citric acid and tartare acid used was Formulation I (3: 2), Formulation II (2: 2), and Formulation III (4: 3). The method used was direct screw press method. The physical quality granule was tested including the flow time, angle of repose, and tap index. The physical quality of the effervescent tablet was tested including uniformity of weight, hardness, friability, and dissolving time. Analysis of the multiform statistics show that variations of citric and tartrate acid gives significant influence towards the angle of repose and hardness of the tablet, but no significant to the time of flow, tap index, uniformity of weight, friability, and dissolving time. The best formula was at the formulation III (citric acid: tartrate acid, 4:3).

Co-Authors Andi Sri Suriati Amal Anggun Mahirotun Nur Sholikhah Frida Ardina Pratiwi Janugraheni Prasetya Ningrum Lija Oktya Artanti Rizqi Fajri Ramadhani Surya Amal Yulian Catur Rini

Title

Found 5 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 5 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 5 Documents
Search