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Lateral-flow immunoassay as a diagnostic test for influenza type A and B in children Ity Sulawati; Amalia Setyati; A. Samik Wahab; M. Juffrie
Paediatrica Indonesiana Vol 48 No 2 (2008): March 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (421.874 KB) | DOI: 10.14238/pi48.2.2008.104-9

Abstract

Background The diagnosis of influenza remains difficult toestablish because of its similar symptoms to those of respiratoryinfection caused by other viruses. The “gold standard” for thediagnosis of influenza is viral culture, which takes time to gainthe result and is expensive as well. A simple, rapid, and easilyused tool for detection of influenza virus type A and B is needed.Objective To assess the accuracy of lateral-flow immunoassay withQuick Vue Influenza A+B ® in detecting influenza virus of typeA and B.Methods This was an observational study designed for diagnostictest. The subjects were children aged 0-14 years old presentingwith acute respiratory infection in primary Health Care Jetis ,Godean I, Godean II and Prof. Dr. Sardjito Hospital Yogyakarta,from October 2005 to May 2007. Specimens were collected fromboth the anterior nares and the throat by physicians for lateral-flow immunoassay with Quick Vue Influenza A+B ® and viralculture as gold standard. Lateral-flow immunoassay was done ineach study centre, nasal specimen was placed in an extractionreagent tube and sent to NAMRU II laboratory.Results There were 255 children enrolled in this study. Lateral-flow immunoassay by Quick Vue Influenza A+B ® has sensitivity70% (CI95% 6;83%), specificity 93% (CI95% 90;97%), positivepredictive value 68% (CI95% 54;82%), negative predictive value94% (CI95% 91;97%), positive likelihood ratio 10,56 (CI95%6,14;18,19) and negative likelihood ratio 0,32 (CI95% 0,21; 0,51).Conclusion Lateral-flow immunoassay (Quick Vue InfluenzaA+B ® ), nasal swab specimen is not accurate to detect influenzavirus A and B in children.
Profil Maternal pada Kasus Kematian Neonatus di Rumah Sakit Umum Daerah (RSUD) Ciawi Ity Sulawati; Dean Ascha Wijaya; William Gilbert Satyanegara
Jurnal Rumpun Ilmu Kesehatan Vol. 3 No. 2 (2023): Juli: Jurnal Rumpun Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jrik.v3i2.2162

Abstract

In 2013, 4.6 million babies died worldwide before their first birthday, with 50% dying on the first day and nearly 75% within the first week. Most stillbirths and premature newborn deaths are attributable to birth complications that are preventable. The maternal profile in neonatal mortality cases plays an important role in understanding the factors that contribute to this high mortality rate. This cross-sectional study aims to determine the maternal profile of neonatal death cases at Ciawi Hospital, which were selected according to the criteria by total sampling based on medical record data from January 1, 2020, to December 31, 2020. The variables utilized in this study include maternal factors such as gestational age, type of delivery, twin pregnancy, presentation of pregnancy, medical condition of the mother, and obstetric problems. The data is presented in a descriptive format. Among the 58 respondents, the average age was 30.26 years, with a higher prevalence of preterm births (55.2%). The most frequently encountered medical condition in the maternal profile of neonatal deaths at Ciawi General Hospital is chronic hypertension. Conversely, the most common obstetric problems are premature rupture of membranes and oligohydramnios. Efforts to address medical issues in mothers can contribute to the reduction of neonatal mortality cases.
Infants with HIV-AIDS Mothers (BIHA): A Case Report Bunga Sherley Aprilia; Ity Sulawati
PROFESSIONAL HEALTH JOURNAL Vol. 7 No. 2 (2026)
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/phj.v7i2.1105

Abstract

HIV (Human Immunodeficiency Virus) is an RNA class retrovirus that specifically attacks the human immune system. A decrease in the immune system in HIV-infected people facilitates various infections, which can lead to the onset of AIDS. AIDS (Acquired Immunodeficiency Syndrome) is a set of clinical symptoms and signs in people with HIV due to opportunistic infections due to a decrease in the immune system. Opportunistic infections can be caused by various viruses, fungi, bacteria, and parasites, and can attack various organs, including the skin, gastrointestinal tract / intestines, lungs, and brain. Infection of infants or children by HIV (Human Immunodeficiency Virus) is mostly transmitted vertically from mother to baby during pregnancy, childbirth, and through breast milk. Horizontal transmission through transfusion of blood products or other transmission such as child sexual abuse occurs less frequently than vertical transmission. A newborn baby from a mother with HIV-AIDS, accompanied by signs of infection in the baby, the patient's mother was found to be reactive on the HIV test and a decrease in CD4. Physical examination results on system examination were good. The results of laboratory support examinations obtained an increase in CRP and hypoglycemia. The diagnosis of infant with mother HIV-AIDS (BIHA) and neonatal infection was established based on the history, physical examination results and supporting examinations of the mother and baby that had been carried out. The patient received main therapy by giving antiretroviral prophylaxis in the form of zidovudine 4mg/kg/time, 2 times a day until the baby is 6 weeks old and antibiotics according to the diagnosis.