A. Samik Wahab
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Liquid crystal thermometry for early detection of hypothermia in newborns in neonatology ward, Sardjito Hospital, Yogyakarta Tunjung Wibowo; Dwikisworo Setyowireni; A. Samik Wahab
Paediatrica Indonesiana Vol 48 No 1 (2008): January 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (620.116 KB) | DOI: 10.14238/pi48.1.2008.5-9

Abstract

Background Hypothermia in neonates increases the risk ofmortality and morbidity such as infection, coagulation disorders,acidosis and hyaline membrane disease. Mercury thermometer iscommonly used to detect hypothermia in newborns, but it has itis not ecological acceptable, difficult to be sterilized, easily broken,difficult to find in some developing countries and needs sometraining before use. A simple, effective and easily used tool fordetection of hypothermia in newborns is needed.Objective To evaluate the ability of liquid crystal thermometry(LCT) in early detection of newborn hypothermia.Methods This study was conducted in the neonatology ward,Sardjito Hospital. The LCT was placed on the abdominal wall.Digital thermometer measurement and LCT observation wereconducted three times in each patient. LCT’s color and bodytemperature were documented by using a pre-coded questionnaire.Results A total of 268 newborns met the inclusion and exclusioncriteria. The pilot study showed that the inter-observer agreementof LCT was 0.75. Positive likelihood ratio during threemeasurements were 22.9 (95%CI 11.47;45.78), 18.97 (95%CI9.43;38.16) and 22.8 (95%CI 11.34;45.83) respectively.Conclusion LCT exhibits good accuracy and is safe to diagnosehypothermia in newborn.
Effect of egg avoidance diet by nursing mothers on the incidence of atopic dermatitis in infants Neti Nurani; Endy Paryanto Prawirohartono; A. Samik Wahab
Paediatrica Indonesiana Vol 48 No 2 (2008): March 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (365.707 KB) | DOI: 10.14238/pi48.2.2008.71-5

Abstract

Background The prevalence of allergic and atopic diseases hasincreased rapidly and remains a social as well as an economicproblem for the patients on account of its chronic nature. In orderto decrease the atopic diseases, especially atopic dermatitis ininfants, nursing mothers should avoid allergenic foods as apreventive sensitization. Egg allergy is the most common cause offood allergy, and is closely related to atopic dermatitis in children.Objective To determine whether egg avoidance diet by nursingmothers could decrease the incidence of atopic dermatitis ininfants.Method We conducted a parallel randomized-controlled trial.Seventy-nine subjects eligible for the study were divided into twogroups: egg avoidance and non-egg avoidance group. Blockrandomization is used for random allocation. Intervention startedsince mothers had had delivery until their children were 4 monthsold. The primary outcomes were clinical atopic dermatitis.Result Atopic dermatitis incidence in maternal egg avoidancegroup was significantly lower than non-avoidance group. Non-avoidance, family history of asthma, and maternal allergy are thefactors significantly influencing atopic dermatitis incidence (OR6.17; OR 4.73; OR 0.14), respectively.Conclusion Egg avoidance by nursing mothers could decrease theincidence of atopic dermatitis in infants. Non-egg avoidance andasthma in the families are factors significantly inducing the incidenceof atopic dermatitis.
Lateral-flow immunoassay as a diagnostic test for influenza type A and B in children Ity Sulawati; Amalia Setyati; A. Samik Wahab; M. Juffrie
Paediatrica Indonesiana Vol 48 No 2 (2008): March 2008
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (421.874 KB) | DOI: 10.14238/pi48.2.2008.104-9

Abstract

Background The diagnosis of influenza remains difficult toestablish because of its similar symptoms to those of respiratoryinfection caused by other viruses. The “gold standard” for thediagnosis of influenza is viral culture, which takes time to gainthe result and is expensive as well. A simple, rapid, and easilyused tool for detection of influenza virus type A and B is needed.Objective To assess the accuracy of lateral-flow immunoassay withQuick Vue Influenza A+B ® in detecting influenza virus of typeA and B.Methods This was an observational study designed for diagnostictest. The subjects were children aged 0-14 years old presentingwith acute respiratory infection in primary Health Care Jetis ,Godean I, Godean II and Prof. Dr. Sardjito Hospital Yogyakarta,from October 2005 to May 2007. Specimens were collected fromboth the anterior nares and the throat by physicians for lateral-flow immunoassay with Quick Vue Influenza A+B ® and viralculture as gold standard. Lateral-flow immunoassay was done ineach study centre, nasal specimen was placed in an extractionreagent tube and sent to NAMRU II laboratory.Results There were 255 children enrolled in this study. Lateral-flow immunoassay by Quick Vue Influenza A+B ® has sensitivity70% (CI95% 6;83%), specificity 93% (CI95% 90;97%), positivepredictive value 68% (CI95% 54;82%), negative predictive value94% (CI95% 91;97%), positive likelihood ratio 10,56 (CI95%6,14;18,19) and negative likelihood ratio 0,32 (CI95% 0,21; 0,51).Conclusion Lateral-flow immunoassay (Quick Vue InfluenzaA+B ® ), nasal swab specimen is not accurate to detect influenzavirus A and B in children.
Association between the absence of colostrum feeding and symptoms of intestinal obstruction or neonatal necrotizing enterocolitis Hananto Wiryo; M. Hakimi; A. Samik Wahab; Pitono Soeparto
Paediatrica Indonesiana Vol 44 No 1 (2004): January 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (341.337 KB) | DOI: 10.14238/pi44.1.2004.7-11

Abstract

Objective To assess the relationship between withholding colos-trum and symptoms of intestinal obstruction (SIO) or neonatal ne-crotizing enterocolitis (NNEC).Methods This was a longitudinal cohort study in four subdistrictsin West Lombok involving mothers and live newborns. Motherswere interviewed about prenatal care, delivery process, and prac-tice of colostrum feedings. Neonates were followed everyday for28 days by field assistants for signs of intestinal obstruction orNNEC. We used X 2 test to analyze the association between theabsence of colostrum feeding and the occurence of SIO and stu-dent t test to compare the average of colostrum feeding betweenthe SIO and the non-SIO group.Results 3420 live newborns between 1993-1994 were observed.1900 mothers gave colostrum while 1520 did not. The incidence ofSIO was 1.8%. There was a significant association between theabsence of colostrum feeding and the occurence of the SIO (RR1.816; 95%CI 1.08-3.06; p=0.028). No infants with NNEC weregiven colostrum.Conclusion The absence of colostrum feeding is an importantrisk factor for the occurence of SIO and NNEC in neonates