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Association between the absence of colostrum feeding and symptoms of intestinal obstruction or neonatal necrotizing enterocolitis Hananto Wiryo; M. Hakimi; A. Samik Wahab; Pitono Soeparto
Paediatrica Indonesiana Vol 44 No 1 (2004): January 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (341.337 KB) | DOI: 10.14238/pi44.1.2004.7-11

Abstract

Objective To assess the relationship between withholding colos-trum and symptoms of intestinal obstruction (SIO) or neonatal ne-crotizing enterocolitis (NNEC).Methods This was a longitudinal cohort study in four subdistrictsin West Lombok involving mothers and live newborns. Motherswere interviewed about prenatal care, delivery process, and prac-tice of colostrum feedings. Neonates were followed everyday for28 days by field assistants for signs of intestinal obstruction orNNEC. We used X 2 test to analyze the association between theabsence of colostrum feeding and the occurence of SIO and stu-dent t test to compare the average of colostrum feeding betweenthe SIO and the non-SIO group.Results 3420 live newborns between 1993-1994 were observed.1900 mothers gave colostrum while 1520 did not. The incidence ofSIO was 1.8%. There was a significant association between theabsence of colostrum feeding and the occurence of the SIO (RR1.816; 95%CI 1.08-3.06; p=0.028). No infants with NNEC weregiven colostrum.Conclusion The absence of colostrum feeding is an importantrisk factor for the occurence of SIO and NNEC in neonates
PERBANDINGAN COMPLETE RESPONSE PENDERITA KANKER OVARIUM STADIUM LANJUT YANG MENDAPAT REJIMEN PACLITAXEL-CARBOPLATIN DENGAN REJIMEN CYCLOPHOSPHAMIDE-ADRIAMYCIN-CISPLATIN SEBAGAI KEMOTERAPI LINI PERTAMA M. Sibuea; M. Lutfi; M. Hakimi
JURNAL KESEHATAN REPRODUKSI Vol 2, No 2 (2015)
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkr.12645

Abstract

PERBANDINGAN COMPLETE RESPONSE PENDERITAKANKER OVARIUM STADIUM LANJUT YANG MENDAPATREJIMEN PACLITAXEL-CARBOPLATIN DENGAN REJIMENCYCLOPHOSPHAMIDE-ADRIAMYCIN-CISPLATIN SEBAGAIKEMOTERAPI LINI PERTAMAM. Sibuea1, M. Lutfi2, M. Hakimi3ABSTRACTBackground: Introduction of Platinum and Paclitaxel has increased survival rate in advanced epithelialovarian cancer. Several studies have been tried to establish the better combination with those anticancerdrugs.Objectives: Comparing complete response (CR) and progression-free survival (PFS) between Paclitaxel-Carboplatin and CAP as a first line treatment in advanced epithelial ovarian cancer.Method: This research used cohort retrospective study. Fifthy-three subjects with epithelial ovarian cancerFIGO stage III and IV were collected from Dr.Sardjito Hospital’s medical record analysis between January2009 and December 2013, and divided into two groups according to chemotherapy regimens. Completeresponse and progression-free survival were determined after cytoreductive surgery and total 6 coursesof chemotherapy.Result and Discussion: The frequency of complete response was similar, 61,5% in Paclitaxel Carboplatingroup as compared with 63% in CAP group (RR 0,977, 95% CI 0,642-1,487, p=1,000). Kaplan-Meier curvesshowed no difference in progression-free survival between the groups, with median PFS was 15 months(95% CI 13,228-16,772) on Paclitaxel-Carboplatin and 14 months on CAP (95% CI 7,686-20,314) (p logrank=0,741). Patients undergo optimal cytoreductive surgery attained more complete response (OR 8,274,95% CI 1,775-38,559, p=0,007) and had a longer PFS than the suboptimal group (17 vs 13 months, p logrank=0,046).Conclusion: Paclitaxel-Carboplatin was not superior compared with CAP regimen as first line chemotherapyin advanced epithelial ovarian cancer. Further evaluation of survival, toxicity profile, and quality of lifewere needed to determine superiority of Paclitaxel-Carboplatin compared with CAP. Optimal cytoreductivesurgery was an independent predictor for a better prognosis.Keywords: advanced ovarian cancer, chemotherapy, Paclitaxel-Carboplatin, CAPABSTRAKLatar belakang: Survival rate penderita kanker ovarium epitelial stadium lanjut meningkat sejakdiperkenalkannya Platinum dan Paclitaxel. Beberapa penelitian telah berusaha untuk menentukankombinasi yang lebih baik dari obat-obatan tersebut.Tujuan: Membandingkan complete response (CR) dan progression-free survival (PFS) antara Paclitaxel-Carboplatin dengan CAP sebagai terapi lini pertama pada kanker ovarium epitelial stadium lanjut.Metode: Penelitian ini menggunakan studi cohort retrospective. Lima puluh tiga subyek dengan kankerovarium epitelial stadium III-IV (FIGO) didapatkan dari analisis rekam medis RSUP Dr. Sardjito mulai Januari2009 hingga Desember 2013, yang terbagi menjadi dua kelompok berdasarkan jenis kemoterapi yang diterima. Complete response dan PFS ditentukan setelah pasien menjalani operasi sitoreduksi dan total 6 siklus kemoterapi.Hasil dan Pembahasan: Frekuensi CR kelompok Paclitaxel Carboplatin (61,4%) serupa dengan kelompokCAP (63%) (RR 0,977, 95% CI 0,642-1,487, p=1,000). Kurva Kaplan-Meier tidak menunjukkan perbedaanPFS di antara kedua kelompok, dengan median PFS Paclitaxel-Carboplatin 15 bulan (95% CI 13,228-16,772)dan CAP 14 bulan (95% CI 7,686-20,314) (p log-rank=0,741). Pasien dengan operasi sitoreduksi optimalmencapai CR lebih banyak (OR 8,274, 95% CI 1,775-38,559, p=0,007) dan median PFS lebih panjang dibandingkan dengan kelompok suboptimal (17 vs 13 bulan, p log-rank=0,046).Kesimpulan: Paclitaxel-Carboplatin tidak lebih superior dibandingkan dengan CAP sebagai kemoterapi linipertama pada kanker ovarium epitelial stadium lanjut. Namun, masih diperlukan pengukuran survival, profiltoksisitas, dan kualitas hidup guna menentukan keunggulan rejimen Paclitaxel-Carboplatin dibandingkan dengan CAP. Operasi sitoreduksi yang optimal merupakan prediktor independen dari prognosis yang lebih baik.Kata kunci: kanker ovarium stadium lanjut, kemoterapi, Paclitaxel-Carboplatin, CAP1,2,3 Bagian Obstetri dan Ginekologi FK UGM/RSUP Dr. Sardjito Yogyakarta
Pendidikan Perilaku Hidup Bersih dan Sehat (PHBS) Pada Anak TK ABA An-Nur Farida Kartini; M. Hakimi; Fitnaningsih Endang Cahyawati; Christiana, Indah; Siti Nurul Fadhilah Sari; Okta Zenita Siti Fatimah; Ana Rofika
Jurnal Pengabdian Masyarakat (JUDIMAS) Vol. 3 No. 1 (2025)
Publisher : Pusat Penelitian dan Pengabdian Masyarakat STIKes Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/judimas.v3i1.391

Abstract

Mengajarkan cara-cara untuk menjaga kebersihan diri dan menjaga kesehatan harus dimulai sejak kecil. Membiasakan anak untuk selalu melakukan hal-hal positif terutama yang berkaitan dengan menjaga kebersihan diri nantinya akan menjadikan suatu hebit yang baik di masa mendatang. Oleh karenanya, untuk membiasakan perilaku tersebut, cara yang dapat dilakukan yakni memberikan pendidikan personal hygiene pada anak prasekolah. Pendidikan prasekolah ini dimaksudkan untuk mengajarkan anak prasekolah/Taman Kanak-kanak (TK) bagaimana cara melakukan personal hygiene. Pada kegiatan tersebut materi-materi yang akan disampaikan adalah apa itu thoharoh, menjaga kebersihan diri sehari-hari. Dengan diketahuinya kedua hal tersebut diharapkan anak-anak sudah sejak kecil menjaga kebersihan dirinya sehingga meminimalisir untuk terjadinya sakit. Solusi yang ditawarkan adalah membekali anak-anak TK mengenai tata cara thoharoh (wudlu, cara membersihkan diri dengan mencuci tangan). Hal tersebut dirasa sangat perlu diajarkan pada anak-anak TK mengingat agar tumbuh hebit yang baik dalam diri anak dimasa yang akan datang. TK yang akan menjadi mitra dalam PkM ini adalah TK ABA AN-Nur. Luaran adalah transfer pengetahuan dan keterampilan mengenai thoharoh dan tata cara menjaga personal hygiene sebagai upaya pemberdayaan masyarakat dibidang Perilaku Hidup Bersih dan Sehat (PHBS).
Positive Childbirth Experience: A Scoping Review Ana Claudia da Costa Guterres; Farida Kartini; M. Hakimi; Joaquim Pinto; Arina Chusnatayaini
Journal Of Nursing Practice Vol. 8 No. 3 (2025): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/jnp.v8i3.818

Abstract

Background: A positive childbirth experience, stating that it must meet or exceed a woman's personal and socio-cultural beliefs and expectations. This includes giving birth to a healthy baby in a clinically and psychologically safe environment, with ongoing practical and emotional support from birth attendants and competent clinical staff. Purpose: This scoping review aimed to identify the best evidence about positive experiences during childbirth, evaluating what factors control and contribute to positive experiences during childbirth. Methods: Databases were searched from 2019 to 2023 from various databases, including PubMed, ScienceDirect, and Cochrane Library/Wiley. As well as using search engines such as Google Scholar and Research Rabbit and selecting them using Rayyan assistance. Critical appraisal and data charting are adopted from the JBI checklist, including cross-sectional, and Qualitative method. Of the 1600 articles identified, only Six met the criteria. Results: The results of this review identified two themes and four subthemes. The two themes are including factors controlling and contribute, and four subthemes such us support and communication factor, participation and empowerment, medical factor and psychology factors. Conclusion: Recommendation for health professionals, especially midwives, is to continue to develop a good and holistic service strategy, by providing support, empowering mothers and also providing good support in order to improve the positive experience during childbirth and minimize negative feedback during childbirth.