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All Journal Jurnal Biologi Tropis
Hamsu Kadriyan
Universitas Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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A healthy lifestyle of the diabetic sufferer to avoid the risk of complications: Literature Review Nini Asri Rahmayunita; Hamsu Kadriyan; Eka Arie Yuliyani
Jurnal Biologi Tropis Vol. 23 No. 2 (2023): April-June
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i2.4923

Abstract

Diabetes Mellitus (DM) is a chronic disease with high blood sugar levels in the blood. DM can cause complications of various diseases because the body can not use blood sugar in the blood cannot be used. The number of DM sufferers, both in the world and in Indonesia, continues to increase from time to time, so this disease is a scourge for everyone. Writing this paper aims to discuss the healthy lifestyle of diabetics to avoid the risk of complications. The most severe disorder of this disease is a chronic metabolic disorder because the pancreas does not produce enough insulin hormone, which has the principal role in regulating and controlling glucose metabolism into energy. Over time, diabetes can interfere with the function of human organs. For example, some organs work improperly, and some should be amputated. One of the most effective efforts to keep blood sugar levels stable is dietary compliance in people with diabetes mellitus has role function. The impact of dietary regulation is maintaining normal-body weight, reducing systolic and diastolic blood pressure, lowering blood glucose levels, improving lipid profiles, increasing insulin receptor sensitivity, and improving the blood coagulation system. This disease requires continuous medical care by carrying out independent health management in patients to prevent acute complications and reduce the risk of long-term complications. It is principal to adopt a healthy lifestyle for diabetic patients in a frame to anticipate the risk of complications.
Effectiveness of Cages Inducing Nasopharyngeal Dysplasia in Wistar Rats (Rattus norvegicus) Gede Rama Hardy Nugraha; Hamsu Kadriyan; Anak Agung Ayu Niti Wedayani; Eka Arie Yuliyani
Jurnal Biologi Tropis Vol. 23 No. 1 (2023): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i1.6088

Abstract

The cage is a place used to put experimental animals in experimental studies to study the mechanism of the disease and its response to therapy. Formaldehyde as a carcinogenic compound can increase the occurrence of chronic inflammation which has the potential to increase the growth of cancer cells in experimental animals due to the stress experienced while in the cage. Therefore, the purpose of this study was to compare the effectiveness of large and small cages induced by formaldehyde 30 ppm against nasopharyngeal dysplasia in Wistar rats. This research is an experimental study with a true experimental design with the type of post-test only control group design. This study used 12 male Wistar rats (Rattus norvegicus) which were divided into two groups, namely the group of Wistar rats which were placed in large cages measuring (30 x 24 x 11.5) cm3 of 6 individuals, and in small cages (27 .5 x 21.5 x 9) cm3 of 6 individuals induced by 30 ppm formaldehyde with a span of 6 hours per day for 16 weeks. The rats were terminated and retro-orbital blood samples were taken to measure MDA levels and nasopharyngeal tissue to assess the degree of dysplasia. The results of this study showed that there was a statistically significant difference (p <0.05) between the degrees of nasopharyngeal dysplasia (p=0.003) and MDA levels (p=0.003) in Wistar rats in small cages and large cages. In this study the effectiveness of small cages was greater than large cages in causing dysplasia in the nasopharyngeal tissue of Wistar rats.
Co-Authors Anak Agung Ayu Niti Wedayani Eka Arie Yuliyani Gede Rama Hardy Nugraha Nini Asri Rahmayunita