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All Journal Jurnal Ilmiah Universitas Batanghari Jambi AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Inovasi Kesehatan Global Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Yuziani Yuziani
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Agriculture, Biological Sciences & Forestry Civil Engineering, Building, Construction & Architecture Dentistry Economics, Econometrics & Finance Education Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

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PENEGAKAN DIAGNOSIS PEMFIGOID BULOSA PADA PENDERITA NON HODGKIN LYMPHOMA Wizar Putri Mellaratna; Yuziani Yuziani
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous Vol. 7 : No. 2 (November, 2021)
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v7i2.5448

Abstract

Pendahuluan: Penyakit bulosa autoimun merupakan penyakit yang relatif jarang dijumpai, yang menyerang kulit dan mukosa dan bersifat fatal. Kasus: Pasien datang dengan keluhan muncul gelembung-gelembung berisi cairan yang sudah pecah dan mengering hampir di seluruh tubuh pasien yang terasa nyeri dan gatal sejak 4 hari yang lalu. Gelembung berisi cairan ini awalnya muncul pada kedua tangan pasien, menyebar ke badan, kaki dan wajah. Status dermatologis ditemukan erosi yang berkrusta, batas tegas, dengan ukuran lentikular sampai dengan numular, distribusi lesi diskret dan generalisata. Hasil pemeriksaan histopatologi didapatkan epidermis sebagian atrofik dengan vacuolated di area basal dan eksositosis limfosit. Sebagian epidermis dengan bula di area subepidermal dengan sel-sel akantolitik. Sebagian epitel tampak nekrotik dengan lumen berisi sel PMN dan debris seluler. Pada dermis tampak serbukan sel radang menahun di perivaskuler. Diskusi: Pemfigoid bulosa umumnya terjadi pada pasien yang berumur lebih dari 60 tahun, insiden puncak pada umur 70 tahun. Pembentukan vesikel dan bula pada kulit normal atau eritematous biasanya tampak menyerupai urtikaria dan infiltrat papul dan plak yang kadang-kadang membentuk pola melingkar. Bula tampak tegang, diameter 1-4 cm, berisi cairan bening dan dapat bertahan selama beberapa hari, meninggalkan area erosi dan berkrusta. Hubungan antara keganasan dengan pemfigoid bulosa umumnya karena faktor usia yang relatif tua dari penderitanya dan sering meningkat pada kasus kanker saluran cerna, saluran urogenital, kanker paru, dan kelainan limfoproliferatif. Kesimpulan: Pemfigoid bulosa sering menyerang usia tua dan dapat terkait dengan keganasan. Pemeriksaan histopatologi diperlukan untuk menyingkirkan diagnosis penyakit bulosa lainnya.Kata kunci: bulosa, pemfigoid, autoimun, limfoma
GAMBARAN PERFORMA INSTRUKTUR KETERAMPILAN KLINIK PROGRAM STUDI PENDIDIKAN DOKTER FAKULTAS KEDOKTERAN UNIVERSITAS MALIKUSSALEH mulyati sri rahayu; Yuziani Yuziani
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Vol. 6: No. 2 (November, 2020)
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v6i2.2399

Abstract

Performa seorang instruktur skill lab sangat berpengaruh  terhadap pencapaian sasaran pembelajaran skill lab. Tujuan penelitian  ini adalah  untuk  mengetahui gambaran performa instruktur skill lab Program Studi Kedokteran di FK  Unimal.  Jenis penelitian ini adalah deskriptif-analitik menggunakan  rancangan  cross sectional. Responden adalah  213 mahasiswa.  Instrumen yang digunakan  adalah “Instrument for Evaluating Clinical Skills lab Teacher’s Didactical Performance”. Hasil penelitian menunjukkan  performa keterampilan mengajar, keterampilan  interpersonal dan komunikasi  dan performa kondisi/strategi pelatihan intruktur keterampila klinik didinilai baik oleh mahasiswa dengan persentase kategori baik sampai sangat baik  lebih dari  90 %.  Kesimpulan penelitian ini menunjukkan  bahwa secara umum  performa instruktur keterampilan klinik di Program Studi Kedokteran FK Unimal sudah baik berdasarkan persepsi mahasiswa. Kata kunci :  keterampilan klinis, instruktur, perfoma mengajar, instrumen
GIANT KONDILOMA AKUMINATA ANAL PADA SEORANG PRIA HOMOSEKSUAL YANG MENDERITA HIV Wizar Putri Mellaratna; Kristina Nadeak; Yuziani Yuziani
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Vol.8 : No.1 (Mei 2022)
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v8i1.7245

Abstract

Pendahuluan : Giant kondiloma akuminata sering dikaitkan dengan HPV tipe 6 dan 11, namun memiliki perbedaan dengan kondiloma anal pada umumnya, seperti papilomatosis yang berbatas tegas, akantosis, rete ridges yang memanjang, dan meningkatnya aktivitas mitosis. Kasus: Pria, umur 33 tahun, dengan keluhan muncul benjolan yang menyerupai kembang kol di sekitar lubang dubur yang terasa gatal sejak 1 tahun yang lalu.  Pemeriksaan status venereologis didapatkan nodul vegetasi, berukuran 8x5x1 cm3, multipel, berbentuk seperti kembang kol, permukaan verokosa, batas tegas, berkelompok, konsistensi padat, warna hiperpigmentasi, tidak dapat digerakkan dan nyeri jika ditekan pada area perianal. Lesi tersebut tidak mudah berdarah. Pasien sudah mendapatkan penotolan TCA (50%) sebanyak tujuh kali namun belum tampak perbaikan, sehingga selanjutnya dilakukan eksisi lesi oleh dokter bedah. Setelah dilakukan pembedahan tampak ada perbaikan lesi. Diskusi: giant kondiloma akuminata merupakan massa eksofitik yang berukuran besar, dapat disertai dengan keluhan gatal, nyeri, perdarahan dan fistel pada lesi. pemeriksaan histopatologi kondiloma akuminata dan giant kondiloma akuminata sangat sulit dibedakan. Mikroskopis giant kondiloma akuminata menunjukkan epitel skuamous berlapis yang mengalami hiperkeratosis, parakeratosis, akantosis dan papilomatosis dengan sedikit sel-sel atypia. Pada epitel juga ditemukan koilositosis. Pada jaringan fibrokolagen didapatkan infiltrat inflamasi kronik. bedah eksisi merupakan terapi lini pertama untuk giant kondiloma akuminata, dengan tingkat kesuksesan mencapai (63-91%) diikuti tingkat relaps yang rendah. Kesimpulan : giant kondiloma akuminata (Buschke-Löwenstein) merupakan penyakit yang sering mengenai kelompok imunosupresif. Giant kondiloma akuminata dapat merupakan prekursor karsinoma sel skuamosa sehingga harus didiagnosis secara tepat dan segera diterapi. Terapi eksisi merupakan terapi lini pertama untuk giant kondiloma akuminata.
Daya Hambat Ekstrak Daun Mengkudu (Morinda citrifolia L.) terhadap Pertumbuhan Bakteri Bacillus cereus Afifah Izzatul Zahra; Yuziani Yuziani; Mulyati Sri Rahayu
Jurnal Ilmiah Universitas Batanghari Jambi Vol 22, No 3 (2022): Oktober
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v22i3.2268

Abstract

Noni (Morinda citrifolia L.) is a plant typical of tropical regions including Indonesia, whose fruits, leaves, seeds, and roots are often used in traditional medicine, including as an antibacterial. This research was conducted to determine the inhibition zone of noni leaf extract (Morinda citrifolia L.). An inhibition test was carried out according to the Kirby-Bauer method with 4 replications on the growth of Bacillus cereus. The results of this study showed that a concentration of 25% produced an average inhibition zone of 9.075 mm, a concentration of 50% produced an average inhibition zone of 8.650 mm, a concentration of 75% produced an average inhibition zone of 9.275 mm, a concentration of 100% produced an average inhibition zone of 10,050 mm, positive control using ciprofloxacin produced an average inhibition zone of 30.475 mm and negative control using DMSO produced an average inhibition zone of 0.000 mm. The results of the comparative test using the Kruskal-Wallis statistical test with a p. value of 0.003 (p<0.005) and the results of the Mann-Whitney test showed that there was a significant difference between P2 and P4 with a value of 0.042 (p<0.005). The conclusion obtained from this study was that the noni leaf extract had a weak zone of inhibition on the growth of Bacillus cereus at a concentration of 100% according to Greenwood's criteria.
Gambaran Faktor-Faktor Pemberian Vitamin A Pada Balita Di Puskesmas Kecamatan Muara Satu Kota Lhokseumawe Tahun 2020 M. Fikri Haikal; Yuziani Yuziani; Mardiati Mardiati
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 4 No. 1 (2024): Maret : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v4i1.3004

Abstract

Vitamin A has biological activity as retinol that can increase the body's resistance to infectious diseases so that it can reduce morbidity and mortality due to vitamin A deficiency, and has an important role for eye health. Vitamin A deficiency (VAD) is the main cause of blindness in children, Aceh Province ranks the fourth lowest in giving vitamin A, it is estimated 30 million toddlers in Indonesia aged 12-59 months, half of whom suffer from VAD. The role of mothers in giving vitamin A is very important, several factors influence the giving of vitamin A to children, that is the level of mother's education, mother's knowledge, mother's visit to Posyandu, mother's job, and the distance from the mother's house to the Posyandu. The purposes of this research are to know the description of mother's education level, mother's knowledge, mother's visit to Posyandu, mother's job, and distance from mother's house to Posyandu in Muara Satu Subdistrict Health Center, Lhokseumawe City. This research method uses a descriptive approach with cross sectional design and sampling using consecutive sampling technique, for data collection is using primary and secondary data. The results of the research on the description of the factors of giving vitamin A at the Muara Satu Subdistrict Health Center, Lhokseumawe City, find that the mother's education level is low 78.1%, mother's knowledge is less 66.8%, mother's visit to Posyandu is high 53.1%, mother does not have a job 88.4%, and the distance from the mother's house to the Posyandu is near 65.6%. The conclusions of this study are the level of mother's education is low, the mother's knowledge is less, the mother's visit to Posyandu is high, the mother's does not have a job, and the distance between the mother's house to Posyandu is near, these variables are a description of the factors of giving vitamin A at Muara Satu Subdistrict Health Center, Lhokseumawe City.
Uji Efek Nefroprotektif Ekstrak Etanol Daun Kari (Murraya Koenigii (L.) Spreng) Terhadap Kadar Blood Urea Nitrogen (BUN) Dan Kreatinin Tikus Putih Jantan Galur Wistar (Rattus Norvegicus) Yang Diinduksi Doksorubisin Yuziani Yuziani; Arvinnia Tanida Harefa; Khairunnisa Z
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 2 No. 2 (2023): Oktober: Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v2i2.1744

Abstract

Cancer is one of the leading causes of death in the world. A highly-effective therapy in cancer is chemotherapy using doxorubicin. Sustainable doxorubicin usage could damage the kidneys due to Reactive Oxygen Species (ROS) formation that could be seen by increased levels of BUN and creatinine. Curry leaves are commonly found in Aceh and has high antioxidant rate so it has the potential to suppress kidney damage due to the use of doxorubicin. These antioxidants could be useful for decreasing levels of BUN and creatinine. The purpose of this research is to test the nephroprotective effect of Ethanol Extract of Curry Leaves (EECL) to prevent kidney failure on doxorubicin induced wistar strain male white rats. The method of this research is experimental with post test only control group design. The number of samples used was 25 rats which were divided into 5 groups. Positive control group (given vitamin E), negative control group (given CMC-Na 0,5%), and treatment groups (given EECL at doses 50 mg/kgBB, 100 mg/kgBB, and 200 mg/kgBB) orally for 7 days straight and doxorubicin 15 mg/kgBB was induced on the 8th day. The results show that the BUN levels in the treatment group given EECL at doses 50 mg/ kgBB and 100 mg/kgBB are close to the positive control group, but the creatinine levels are still significantly different. Meanwhile, the treatment group that was given EECL at dose 200 mg/kgBB, both BUN and creatinine levels, are close to the positive control group. The conclusion of this study is that EECL has a nephroprotective effect on doxorubicin induced rats and the most effective dose is 200 mg/kgBB.
Gambaran Penggunaan Antibiotik Profilaksis pada Pasien Bedah Appendicitis di Rumah Sakit Arun Lhokseumawe Tahun 2020-2022 Khaira Maulina; Anna Millizia; Yuziani Yuziani
Inovasi Kesehatan Global Vol. 2 No. 4 (2025): November: Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i4.2345

Abstract

Appendicitis is a common health problem in Indonesia. Appendicitis requires surgery because it's an acute inflammation. Appendicitis can be treated with surgery to remove the appendix, namely appendectomy, by performing surgery on the abdominal tract. Appendectomy is a clean-contaminated surgery that can cause surgical wound infection in around 5-15% of cases. Prophylactic antibiotics are included in infection prevention. It is important to evaluate the use of prophylactic antibiotics in appendicitis surgery patients to reduce drug side effects and prevent surgical site infections. Infections can be caused by microorganisms such as pathogenic bacteria, and antibiotics are the most commonly used drugs to treat such infections. SSI can cause morbidity, mortality, increased length of stay, and increased patient care costs. The researchers chose Arun Lhokseumawe Hospital as the research site because no research had ever been conducted at Arun Lhokseumawe Hospital on the use of prophylactic antibiotics in appendicitis surgery patients. Preliminary survey results based on Arun Lhokseumawe Hospital medical records from 2020 to 2022 showed that 202 patients underwent surgery. The purpose of this study was to determine the profile of prophylactic antibiotic use in appendicitis surgery patients using the Gyssens method at Arun Lhokseumawe Hospital from 2020 to 2022. This study was observational in nature, using total sampling as the sampling technique. The Results of the study showed that the most frequently used type of prophylactic antibiotic was Cefotaxime (53.5%) and the appropriateness of antibiotic use was category 0 (97%) because it was appropriate and category IVA (3%) because there were other antibiotics that were more effective. It can be concluded that Cefotaxime is the most frequently used antibiotic, and the appropriateness of prophylactic antibiotics at Arun Hospital in Lhokseumawe City is already appropriate.
Gambaran Faktor-Faktor Pemberian Vitamin A Pada Balita Di Puskesmas Kecamatan Muara Satu Kota Lhokseumawe Tahun 2020 M. Fikri Haikal; Yuziani Yuziani; Mardiati Mardiati
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 4 No. 1 (2024): Maret : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v4i1.3004

Abstract

Vitamin A has biological activity as retinol that can increase the body's resistance to infectious diseases so that it can reduce morbidity and mortality due to vitamin A deficiency, and has an important role for eye health. Vitamin A deficiency (VAD) is the main cause of blindness in children, Aceh Province ranks the fourth lowest in giving vitamin A, it is estimated 30 million toddlers in Indonesia aged 12-59 months, half of whom suffer from VAD. The role of mothers in giving vitamin A is very important, several factors influence the giving of vitamin A to children, that is the level of mother's education, mother's knowledge, mother's visit to Posyandu, mother's job, and the distance from the mother's house to the Posyandu. The purposes of this research are to know the description of mother's education level, mother's knowledge, mother's visit to Posyandu, mother's job, and distance from mother's house to Posyandu in Muara Satu Subdistrict Health Center, Lhokseumawe City. This research method uses a descriptive approach with cross sectional design and sampling using consecutive sampling technique, for data collection is using primary and secondary data. The results of the research on the description of the factors of giving vitamin A at the Muara Satu Subdistrict Health Center, Lhokseumawe City, find that the mother's education level is low 78.1%, mother's knowledge is less 66.8%, mother's visit to Posyandu is high 53.1%, mother does not have a job 88.4%, and the distance from the mother's house to the Posyandu is near 65.6%. The conclusions of this study are the level of mother's education is low, the mother's knowledge is less, the mother's visit to Posyandu is high, the mother's does not have a job, and the distance between the mother's house to Posyandu is near, these variables are a description of the factors of giving vitamin A at Muara Satu Subdistrict Health Center, Lhokseumawe City.
Evaluasi Penerapan Terapi MDT pada Kasus Kusta di Kota Lhokseumawe Haur Syakira Radra; Yuziani Yuziani; Mohamad Mimbar Topik
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v4i1.4542

Abstract

Leprosy is a chronic infectious disease caused by the bacterium Mycobacterium leprae. It is a neglected tropical disease, still found in more than 120 countries, with more than 200,000 new cases reported each year.. The purpose of this research is to characterize leprosy patients in Lhokseumawe City and to describe the Multi Drug Therapy therapy. Information about the therapy, including the kind of leprosy, age, gender, employment, and the precise period of treatment, is evaluated in this research. Instruments for measurement were derived using data collected from medical records in this cross-sectional observational investigation. A whole sampling population was used in the sampling procedure, with 42 respondents making up the sample. Based on these findings, MB leprosy is the most frequent form of the disease (90.5% of cases), men make up the majority (64.3%) of leprosy patients, and the majority of leprosy patients are adults (88.1%). Results from the MDT treatment protocol indicated that 76.2% of patients were considered to have finished therapy (RFT), with the biggest occupational category being patients who did not work, accounting for 50% of the total. It is imperative that leprosy officers work to promote health promotion in order to raise awareness, decrease negative stigma, and speed up the discovery of leprosy cases
Co-Authors Afifah Izzatul Zahra Anna Millizia Arvinnia Tanida Harefa Haur Syakira Radra Khaira Maulina Khairunnisa Z Kristina Nadeak M. Fikri Haikal Mardiati Mardiati Mohamad Mimbar Topik Mulyati Sri Rahayu Mulyati Sri Sri Rahayu Wizar Putri Mellaratna