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All Journal Nusantara Medical Science Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) International Journal of Health Science & Medical Research
Idham Jaya Ganda
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Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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IMUNOGLOBULIN A DI DEMAM BERDARAH DENGUE Iwan Joseph; Uleng Bahrun; Idham Jaya Ganda; Mansyur Arif
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 18, No 1 (2011)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v18i1.350

Abstract

Recently several serology tests have been used to detect IgM and IgG antidengue, and NS1 antigen. On the last study was launched a new diagnose test using immunochromatography method to detect the specific antidengue IgA antibody. The aim of this study was to evaluate the IgA antidengue performance using immunochromatography method in Dengue Hemorrhagic Fever patients. The study was carried out during March up to July 2010 by a cross sectional method. The samples taken were 1–14 year‘s old patients from the Infectious Tropical Sub Division of the Department of Paediatric, Dr. Wahidin Sudirohusodo Hospital, Makassar. The samples were diagnosed Dengue Hemorrhagic Fever based on the criteria of WHO 1997 and they also subjected to IgM and IgG serology tests as well. The test for IgA is using immunochromatography method. The data was analyzed by Spearman Correlation Test. From the total 40 samples, which consist of 16 (40%) male and 24 women (60%), generally were taken on the fourth day until the sixth day of onset. There were more IgA anti Dengue detected rather than IgM on the secondary infection. The researchers found moderate correlation among the IgA test with IgM (+), IgG (+), or both positive. Based on this study so far it can be concluded that the Dengue IgA test can be used to detect the primary or secondary Dengue virus infection.
ANALYSIS OF VITAMIN D LEVELS IN CHILDREN WITH THALASSEMIA BETA Nadirah Rasyid Ridha; Johan Gautama; Idham Jaya Ganda
International Journal of Health Science & Medical Research Vol 1, No 1 (2022): February 2022
Publisher : UNG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (475.705 KB) | DOI: 10.37905/ijhsmr.v1i1.13585

Abstract

Background : Beta Thalassemia is a genetic disorder inherited by autosomal recessive and has spread throughout the world, including Indonesia. Beta thalassemia requires lifelong transfusions, which can cause an accumulation of iron in the skin, liver, and kidneys, resulting in a decrease in vitamin D synthesis.Purpose : This study aims to analyze the levels of 25-OH-Vitamin D in beta thalassemia.Method : This study used a cross-sectional design and was conducted at Dr. Wahidin Sudirohusodo Hospital from April to July 2021. The population of this study was patients diagnosed with beta thalassemia and non-thalassemia (controls) who met inclusion criteria. This study compared vitamin D levels in beta thalassemia and non-thalassemia patients.Results : This study involved 60 children aged 6 months to 18 years, who were divided into 2 groups: 30 children in the beta thalassemia group and 30 in the non-thalassemia group. In this study, the levels of 25-OH-Vitamin D were lower in beta thalassemia children compared to non-thalassemic children, with a p value =0.012. Children with beta-thalassemia have a 4.33 times higher risk of vitamin D deficiency compared to non-thalassemic children. With a p value =0.023, 25-OH-Vitamin D levels were significantly lower in beta HbE thalassemia children compared to beta thalassemia major children.Conclusion :Levels of 25-OH-Vitamin D in beta thalassemia children were lower than in non-thalassemic children. Levels of 25-OH-Vitamin D in children with beta HbE thalassemia are lower than in children with beta thalassemia major.
Positive Fluid Balance as a Prognosis Predictor in Pediatric Sepsis Patients: A Retrospective Cohort Study Gosal, Astri; Siti Aizah Lawang; Idham Jaya Ganda; Hadia Angriani; Ratna Dewi Artati; Jusli
Nusantara Medical Science Journal Volume 8 Issue 1, January - June 2023
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v8i1.23615

Abstract

Introduction: Sepsis is one of the leading causes of infant and child morbidity and mortality worldwide. Fluid administration is an important way to reduce morbidity and mortality in septic patients with low blood flow and shock, since sepsis is often linked to low blood volume. The purpose of this study was to investigate the relationship between positive fluid balance and the outcome of pediatric sepsis patients. Methods: A retrospective cohort analysis of 80 pediatric patients diagnosed with sepsis using the 2005 International Pediatric Sepsis Consensus Conference (IPSCC) criteria. The positive fluid balance value was obtained from medical records and was evaluated using the Receiver Operating Characteristic (ROC) curve method. Results: Positive fluid balance was found to have a significant link with the outcome of pediatric sepsis patients (p<0.05).The positive fluid balance value of ≥4.61% was associated with mortality in pediatric patients with sepsis, with a sensitivity value of 62.79%, specificity of 62.16%, negative predictive value of 58.95%, and positive predictive value of 65.85%. The value of fluid balance in the first 24 hours of Pediatric Incentive Care Unit (PICU) care was higher in septic pediatric patients who died compared to those who improved, but not significantly (p=0.37). The value of total fluid balance during PICU care was higher in septic pediatric patients who died compared to those who improved (p<001). Conclusions: Positive fluid balance with a cut-off value of 4.61% can be used as a prognostic factor in pediatric patients with sepsis.
Co-Authors Gosal, Astri Hadia Angriani Iwan Joseph Johan Gautama Jusli Mansyur Arif Nadirah Rasyid Ridha, Nadirah Rasyid Ratna Dewi Artati Siti Aizah Lawang Uleng Bahrun