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All Journal Majalah Ilmiah Sultan Agung Medali Jurnal : Media Dental Intelektual ODONTO Dental Journal Jurnal Kesehatan Gigi Dental Journal (Majalah Kedokteran Gigi) Odonto dental journal
Andina Rizkia Putri Kusuma
Department Of Conservative Dentistry, Faculty Of Dentistry, Universitas Islam Sultan Agung, Semarang
Dentistry Education Health Professions Medicine & Pharmacology Public Health

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Efectivenesse of three pulp capping materials on cellular response of pulp tissue Andina Rizkia Putri Kusuma
Odonto : Dental Journal Vol 10, No 1 (2023): July 2023
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.10.1.132-139

Abstract

Background: Pulp capping is a treatment that utilizes medications to preserve pulp vitality. Ca(OH)2, mineral trioxide aggregate (MTA), and biodentine are presently the most common pulp capping medications. As pulp capping materials, Ca(OH)2 and MTA are known to have several weaknesses. Biodentine has been created in an effort to mitigate the drawbacks of Ca(OH)2 and MTA. Thus, the purpose of this study is to compare the efficacy of three pulp capping medications in reducing inflammation and accelerating pulp regeneration. Methods: Total 48 male Wistar rats, that were divided into 4 groups, namely 1st control group, 2nd MTA group, 3rd biodentine group, and 4th Ca(OH)2 group. Maxillary 1st molar teeth of rats were prepared using round bur no. 080 perpendicular to the tooth axis to a depth of 1mm, until a reddish color appeared on the pulp. Furthermore, pulp capping medicament was applied to the deepest points, and temporary fillings were made with Zn2(PO4)3. Decapitation was carried out on days 4 and 7 to count the number of neutrophil cells, macrophages, odontoblast-like cells, and fibroblasts. Data were analyzed using One-way ANOVA (p
Antibacterial Efficacy of Ethyl Acetate Fraction of Siwak (Salvadora persica)-NaOCl Combination as a Root Canal Irrigant against Enterococcus faecalis: An In Vitro Study Kusuma, Andina Rizkia Putri; Ratih, Diatri Nari; Irnawati, Dyah -; Nuryono, Nuryono -
Jurnal Kesehatan Gigi Vol. 12 No. 1 (2025): December 2025
Publisher : Jurusan Kesehatan Gigi, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkg.v12i1.13605

Abstract

Root canal irrigant is a very important factor in supporting the success of root canal treatment. The currently recommended combination of sodium hypochlorite (NaOCl), ethylenediamintetraacetic acid (EDTA), and chlorhexidine has many drawbacks including toxicity to periapical tissues, bad taste, negative interactions between ingredients, and extended application time. Siwak (Salvadora persica) stem extract has been widely studied in its use as a dental material, including as a root canal irrigant. This study aims to formulate the ethyl acetate fraction of siwak with low concentration NaOCl, and test its antibacterial potential against E. faecalis. This research used 9 groups, namely the ethyl acetate fraction (FEA) of siwak ethanol extract with the concentrations of 1.25 mg/ml, 2.5 mg/ml, 5 mg/ml, a combination of FEA siwak 1.25 mg/ml + NaOCl 1.25%, FEA siwak 2.5 mg/ml + NaOCl 1.25%, FEA siwak 5 mg/ml + NaOCl 1.25%, NaOCl 1,25%, saline, and chlorhexidine. Based on the number of colony counts, the most significant inhibition was seen in the combination group of FEA siwak 5 mg/ml + NaOCl 1.25%. Data analysis was carried out using the One Way ANOVA test with a significance value of 0.00 (p <0.05) followed by the Post Hoc LSD test with a significance value of 0.130 (p>0.05) in the comparison between the combination group of FEA siwak 5 mg/ml + NaOCl 1.25% with chlorhexidine. The combination of FEA siwak 5 mg/ml + NaOCl 1.25% has the same effectiveness as chlorhexidine 2% in inhibiting E. faecalis bacteria, and potential as a root canal irrigant. 
Co-Authors Aning Susilowati Arlina Nurhapsari Chariza Hanum Mayvita Iskandar Dewi Ratma Utami Diatri Nari Ratih Hardita Bicevani Mulya Hardita Bicevani Mulya Irnawati, Dyah - Megya Agustina Dentisari Moh. Yusuf Muhammad Dian Firdausy, Muhammad Nuryono, Nuryono - Rahmawati Sri Praptiningsih Rochman Mujayanto Rosida Intan Andica Syuhada Setiawan Tifani Ardiana Welly Anggarani Welly Anggarani Windy Pretyani Kusumawati Winnugroho Wiratman, Manfaluthy Hakim, Tiara Aninditha, Aru W. Sudoyo, Joedo Prihartono