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All Journal Majalah Ilmiah Sultan Agung Medali Jurnal : Media Dental Intelektual ODONTO Dental Journal Jurnal Kesehatan Gigi Dental Journal (Majalah Kedokteran Gigi) Interdental Jurnal Kedokteran Gigi (IJKG) Odonto dental journal
Andina Rizkia Putri Kusuma
Department Of Conservative Dentistry, Faculty Of Dentistry, Universitas Islam Sultan Agung, Semarang
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Medicine & Pharmacology Public Health

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Efectivenesse of three pulp capping materials on cellular response of pulp tissue Kusuma, Andina Rizkia Putri
Odonto : Dental Journal Vol 10, No 1 (2023): July 2023
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.10.1.132-139

Abstract

Background: Pulp capping is a treatment that utilizes medications to preserve pulp vitality. Ca(OH)2, mineral trioxide aggregate (MTA), and biodentine are presently the most common pulp capping medications. As pulp capping materials, Ca(OH)2 and MTA are known to have several weaknesses. Biodentine has been created in an effort to mitigate the drawbacks of Ca(OH)2 and MTA. Thus, the purpose of this study is to compare the efficacy of three pulp capping medications in reducing inflammation and accelerating pulp regeneration. Methods: Total 48 male Wistar rats, that were divided into 4 groups, namely 1st control group, 2nd MTA group, 3rd biodentine group, and 4th Ca(OH)2 group. Maxillary 1st molar teeth of rats were prepared using round bur no. 080 perpendicular to the tooth axis to a depth of 1mm, until a reddish color appeared on the pulp. Furthermore, pulp capping medicament was applied to the deepest points, and temporary fillings were made with Zn2(PO4)3. Decapitation was carried out on days 4 and 7 to count the number of neutrophil cells, macrophages, odontoblast-like cells, and fibroblasts. Data were analyzed using One-way ANOVA (p
LEVELS OF MALONDIALDEHYDE AND CALCITONIN GENE-RELATED PEPTIDE IN PULP INFLAMMATION DUE TO LPS INDUCTION DURATION Nurhapsari, Arlina; Kusuma, Andina Rizkia Putri
Odonto : Dental Journal Vol 9, No 1 (2022): July 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.9.1.148-152

Abstract

Background: Administration Lipopolysaccharide (LPS) to pulp tissue might produce inflammation. Inflammation occurs, which can lead to oxidative stress and neuropeptides release. Malondialdehyde (MDA) is an oxidative stress measure, while calcitonin gene-related peptide (CGRP) is a neuropeptide found in large amounts in the pulp. This study attempted to analyze levels of CGRP and MDA in LPS inflamed rat pulp tissueMethode: Wistar rats' maxillary incisors were treated to LPS stimulation. A total of 30 mice were separated into six groups, each with five animals. The groups were created by administering LPS to the pulp for 6, 12, 24, 48, and 72 hours. Rat without pulpal exposure (0 hour) served as controls. Enzyme-linked Immunosorbent Assay (ELISA) was used to measure the levels of MDA and CGRP in the pulp tissue.Result : MDA and CGRP levels were found to be significantly different in all groups (p0.05 mohon diberi keterangan apakah </>/=). With LPS administration, MDA levels increased on average, whereas CGRP levels fluctuated. Conclusion: The presence of inflammation in the pulp was shown by changes in MDA and CGRP levels after 6 hours of LPS injection. The effect of rising MDA levels on inflamed pulp tissue did not produce effects that were directly proportional to or vice versa with CGRP levels that showed fluctuated.
Efectivenesse of three pulp capping materials on cellular response of pulp tissue Kusuma, Andina Rizkia Putri
Odonto : Dental Journal Vol 10, No 1 (2023): July 2023
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.10.1.132-139

Abstract

Background: Pulp capping is a treatment that utilizes medications to preserve pulp vitality. Ca(OH)2, mineral trioxide aggregate (MTA), and biodentine are presently the most common pulp capping medications. As pulp capping materials, Ca(OH)2 and MTA are known to have several weaknesses. Biodentine has been created in an effort to mitigate the drawbacks of Ca(OH)2 and MTA. Thus, the purpose of this study is to compare the efficacy of three pulp capping medications in reducing inflammation and accelerating pulp regeneration. Methods: Total 48 male Wistar rats, that were divided into 4 groups, namely 1st control group, 2nd MTA group, 3rd biodentine group, and 4th Ca(OH)2 group. Maxillary 1st molar teeth of rats were prepared using round bur no. 080 perpendicular to the tooth axis to a depth of 1mm, until a reddish color appeared on the pulp. Furthermore, pulp capping medicament was applied to the deepest points, and temporary fillings were made with Zn2(PO4)3. Decapitation was carried out on days 4 and 7 to count the number of neutrophil cells, macrophages, odontoblast-like cells, and fibroblasts. Data were analyzed using One-way ANOVA (p
Comparison of Color Uptake Effectiveness Between Disclosing Agent Tablets Derived from Mangosteen (Garcinia mangostana L.) Peel Extract and Its Fractions on Dental Plaque Muslimah, Indah; Poetri, Adisty Restu; Kusuma, Andina Rizkia Putri; Kodir, Ade Ismail Abdul
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 3 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i3.11346

Abstract

Introduction: Plaque is a transparent layer that requires a coloring agent in the form of a disclosing agent to visualize it. Erythrosine, as one of the frequently used disclosing agents, has potential toxic side effects if used in the long term. Therefore, this study aims to compare the effectiveness of color absorption between tablets based on extracts and fractions of mangosteen fruit peel (Garcinia mangostana L.) with erythrosine as a control. Materials and Methods: This study employed a laboratory experimental design with a post-test-only controlled group design. A total of 36 healthy dental samples were divided into 9 groups, which were soaked in saliva for 8, 24, and 48 hours. After plaque formation, tablets of extracts, mangosteen peel fractions, and erythrosine were applied to the teeth. Results and Discussion: The results of analysis using the One-way ANOVA test showed that erythrosine tablets had significantly higher color absorption than the extract and mangosteen peel fraction tablets. Conclusion: Erythrosine is still a more effective option in highlighting dental plaque, but mangosteen peel-based tablets can be a safer natural alternative with potential for further development. Further research is recommended to optimize the formulation of mangosteen peel tablets to improve their effectiveness and convenience in clinical applications.
Co-Authors Aning Susilowati Arlina Nurhapsari Chariza Hanum Mayvita Iskandar Dewi Ratma Utami Diatri Nari Ratih Hardita Bicevani Mulya Hardita Bicevani Mulya Irnawati, Dyah - Kodir, Ade Ismail Abdul Megya Agustina Dentisari Moh. Yusuf Muhammad Dian Firdausy, Muhammad Muslimah, Indah Nuryono, Nuryono - Poetri, Adisty Restu Rahmawati Sri Praptiningsih Rochman Mujayanto Rosida Intan Andica Syuhada Setiawan Tiara Aninditha Tifani Ardiana Welly Anggarani Welly Anggarani Windy Pretyani Kusumawati