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Journal : Muhammadiyah Medical Journal

Potential of Sweet Basil (Ocimum basilicum) as a Hepatoprotector Agent for Liver Injury Related to Drugs Renovaldi, Dede; Adam, Abdul Khalik
Muhammadiyah Medical Journal Vol 1, No 2 (2020): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (773.047 KB) | DOI: 10.24853/mmj.1.2.63-68

Abstract

The use of drugs is one of the most common causes of liver injury, because the liver is the main organ that metabolizes drugs. Little is currently done if there is a liver injury due to the hepatotoxic side effects of a drug. Herbal plants have active natural compounds that have pharmacological effects so they are widely used as alternative treatments. Sweet basil (Ocimum basilicum) is one of the most cultivated plants in Asia. Studies on the use of Ocimum basilicum in medicine have been carried out, one of which is the hepatoprotector effect. Studies indicate that Ocimum basilicum is rich in high antioxidant content (flavonoids, saponins, tannins, sterols, triterpenes, and rosmaniric acid) capable of providing hepatoprotector effects by helping the regeneration process of hepatocyte cells that are damaged by hepatotoxic agents and significantly decreasing liver damage biomarkers. The purpose of this review is to explain the potential of Ocimum basilicum as a hepatoprotective agent for liver injury associated with drugs. The conclusion of this review is Ocimum basilicum has high potential in its utilization as a hepatoprotector against liver injury mainly related to the consumption of drugs that have hepatotoxic effects.
Comparison of Depression Levels between Medical and Engineering Students at Universitas Muhammadiyah Jakarta Nadila, Riska Indri; Renovaldi, Dede
Muhammadiyah Medical Journal Vol. 6 No. 1 (2025): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.6.1.50-58

Abstract

Background: Medicine and engineering faculties are noted for their vigorous learning intensity and high degree of academic difficulty, making them vulnerable to mental health illnesses such as depression. Purpose: To compare depression levels between medical and engineering students at Universitas Muhammadiyah Jakarta. Method: This study employed a cross-sectional design. Medical and Engineering students were given the Beck Depression Inventory II (BDI-II) questionnaire. The sample size consists of 152 people, collected through purposive sampling. The Mann-Whitney test was used for analysis (p = 0.05, 95% CI). Result: Age 21 (25.0%) was the most frequent age, while age 17 (2.6%) was the least frequent. Based on gender, the male respondents consisted of 87 people (57.2%), and the female respondents consisted of 65 (42.8%). The medical and engineering student groups each had 76 respondents (50.0%). Only 40.8% of medical students reported depression, compared to 63.1% of engineering students (p = 0.001). Conclusion: Engineering students experience more depression than medical students.