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All Journal MABIS: Manajemen dan Bisnis Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML)
Indarini Indarini
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Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Health Professions Medicine & Pharmacology Neuroscience Social Sciences

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CASPASE-3 AKTIF DI LEUKEMIA MIELOSITIK AKUT (LMA) DAN LEUKEMIA LIMFOBLASTIK AKUT (LLA) Agus Setiawan; Indarini Indarini; Lyana Setiawan; Siti Boedina Kresno; Nugroho Prayogo; Arini Setiawati
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 19, No 3 (2013)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v19i3.411

Abstract

Dysregulation of apoptosis plays an essential role either in leukemogenesis or treatment response. Caspase-3 is a cysteine protease that functions as the final common mediator of apoptosis. The expression of the active caspase-3 is presumed as a predictor of prognosis and is able to predict the chemotherapy sensitivity. The aim of this study is to identify and to know the profile of active caspase-3 in Acute Myeloid Leukaemia (AML) and Acute Lymphoblastic Leukaemia (ALL), to correlate its expression in marrow and peripheral blood mononuclear cells, and to verify the extent of its use as a complete remission predictor after induction treatment. The study subjects consisted of patients who were diagnosed as AML and ALL with marrow and peripheral blood examination performed at the Department of Clinical Pathology Dharmais Cancer Hospital and CiptoMangunkusumo Hospital. Based on this study, it is revealed that the active caspase-3 expression in mononuclear marrow cells was higher in AML compared to ALL (p=0.033), active caspase-3 expression in marrow showed a strong correlation (r=0.764; p=0.001) to peripheral blood mononuclear cells in ALL and a medium correlation (r=0.594; p=0.042) in AML. The expression of the active caspase-3 in ALL patients was lower in complete remission patients compared to the non-complete remission patients. Regarding to this study it is recommended to measure the active caspase-3 along with molecules integrating in apoptosis signaling pathways such as cytochrome-c and in the formation of apoptosome.
THE EFFECT OF BRAND IMAGE ELEMENTS ON PRICE PREMIUM AND BRAND LOYALTY OF SAMYANG BRAND INSTANT NOODLE IN SURABAYA Ing Erviana; Dudi Anandya; Indarini Indarini
Manajemen dan Bisnis Vol 15, No 2 (2016): SEPTEMBER 2016
Publisher : Department of Management - Faculty of Business and Economics. Universitas Surabaya.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/jmb.v15i2.282

Abstract

This research aims to investigate the positive relationship between brand image’s elements which are brand awareness, perceived quality, country of origin, social image, and uniqueness, to price premium and brand loyalty for Samyang instant noodles purchase in Surabaya. This research showed that brand awareness, perceived quality, and country of origin do not significantly correlated to price premium and brand loyalty while social image and uniqueness correlate positively to price premium and brand loyalty so it can be concluded that only social image and uniqueness which affect price premium and brand loyalty. Samyang’s instant noodle distribution manager in Indonesia need to focus on social image and uniqueness and need to ignore brand awareness, perceived quality, and country of origin to get price premium and brand loyalty.
THE IMPACT OF SOCIAL MEDIA MARKETING ON BRAND LOYALTY: THE MEDIATION EFFECT OF BRAND-VALUE CONSCIOUSNESS TOWARDS ADIDAS BRAND IN INDONESIA Archie Edrick Hermanus; Silvia Margaretha; Indarini Indarini
Manajemen dan Bisnis Vol 15, No 2 (2016): SEPTEMBER 2016
Publisher : Department of Management - Faculty of Business and Economics. Universitas Surabaya.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/jmb.v15i2.281

Abstract

The purpose of this study is to investigate the impact of social media marketing on brand loyalty with the mediation effect of brand-value consciousness towards Adidas brand in Indonesia. The analysis method in this study is using structural equation modeling (SEM). Object of this current study is highschool students (or equal) and college students who is using social media and follow Adidas on social media, on the amount of 150 people. Data processing using softwares such as SPSS – PASW Statistics version 18 for Windows OS and IBM – AMOS version 22 for Windows OS. The results of this study indicated that social media marketing has a significant effect on brand loyalty; brand consciousness and value consciousness mediate the relationship beetwen social media marketing and brand loyalty.
Co-Authors Archie Edrick Hermanus Arini Setiawati Dudi Anandya Ing Erviana Laksono Trisnantoro Lyana Setiawan Nugroho Prayogo Silvia Margaretha Siti Boedina Kresno