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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan International Journal of Integrated Health Sciences Majalah Kedokteran Bandung Althea Medical Journal Sari Pediatri Indonesian Journal for Health Sciences (IJHS) Jurnal Biomedika dan Kesehatan Journal Integration of Management Studies Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Dedi Rachmadi
Departemen Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Padjadjaran-Rumah Sakit Dr. Hasan Sadikin Bandung
Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Prevalensi dan Faktor Risiko Catheter Associated Urinary Tract Infection di Unit Perawatan Intensif Anak Febrianti, Sindy Amalia; Alam, Anggraini; Rachmadi, Dedi
Sari Pediatri Vol 25, No 4 (2023)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp25.4.2023.249-56

Abstract

Latar belakang. Sekitar 80% Infeksi Saluran Kemih yang didapat di rumah sakit yang berhubungan dengan penggunaan kateter urin atau catheter-associated urinary tract infection. Beberapa faktor risiko dianggap memengaruhi kejadian CAUTI. Hingga saat ini, prevalensi CAUTI pasien anak di Rumah Sakit Dr. Hasan Sadikin belum tercatat dan pola kuman penyebab CAUTI serta sensitivitas antibiotik dapat bervariasi antar rumah sakit.Tujuan. Mengetahui prevalensi catheter-associated urinary tract infection di Unit Perawatan Intensif Anak Rumah Sakit Hasan Sadikin dan menganalisis faktor risiko yang menyebabkannya.Metode. Penelitian ini merupakan studi observasional analitik dengan metode kasus-kontrol menggunakan data sekunder dari rekam medis pasien yang terpasang kateter urin, dirawat di Unit Perawatan Intensif Anak Rumah Sakit Umum Pusat Dr. Hasan Sadikin tahun 2017-2019, baik terdiagnosis CAUTI maupun tidak terdiagnosis CAUTI.Hasil. Sebanyak 138 subjek memenuhi kriteria inklusi penelitian, kemudian dikelompokkan masing-masing 69 pasien kriteria kasus dan kontrol. Sebagian besar subjek berjenis kelamin laki-laki. Usia terbanyak adalah 11-18 tahun (33,3%) pada kelompok kasus dengan status gizi normal (50,7%). Dari enam faktor risiko yang diteliti hanya satu yang menunjukkan perbedaan bermakna yaitu diagnosis awal saat dirawat (sepsis). Kesimpulan. Prevalensi CAUTI cukup tinggi. terutama terkait dengan diagnosis awal sepsis. Penelitian lanjutan perlu dilakukan dan pemeriksaan rutin kultur urin dianjurkan untuk diagnosis dan terapi yang efektif.
ALKYLATING AGENT TREATMENT IN CHILDREN WITH STEROID-RESISTANT NEPHROTIC SYNDROME IN WEST JAVA Widiasta, Ahmedz; Rachmadi, Dedi; Hilmanto, Dany
Indonesian Journal of Health Science Vol 9 No 1 (2025): March
Publisher : Universitas Muhammadiyah Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24269/ijhs.v9i1.8383

Abstract

Objective: to evaluate SRNS therapy in children. Steroid-resistant nephrotic syndrome (SRNS) is one of the most common causes of chronic kidney disease in children. Kidney Disease Initiative for Global Outcome (KDIGO) no longer recommends an alkylating agent (AA) as the treatment protocol for SRNS, still in some developing countries, such as Indonesia, there are some limitations in obtaining immunosuppressive agents other than AA. Method: Data were collected from the medical records of SRNS children with SRNS aged between 1 and 18 years from January 2016 to December 2021. The data included time to remission, adverse effects, and relapse-free period after receiving AA treatment based on the lesion type.  Results: Among the 369 patients enrolled from January 2016 to December 2018, 244 patients (66.12%) had remission with AA, and 125 patients experienced persistent proteinuria. Most of them had remission during the fifth to seventh cycles of intravenous AA (after 6 – 8 months). None of the patients experienced severe adverse effects of AA. Only a small proportion of patients had chronic kidney disease (CKD) stage II–V during follow-up. Conclusions: AA is still effective in treating SRNS in children, with only a few and less harmful adverse effects
Nephropathy and Encephalopathy in an Indonesian Patient with Dengue Viral Infection Rachmadi, Dedi; Anggara, Mohamad Yanuar
International Journal of Integrated Health Sciences Vol 1, No 1 (2013)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (331.756 KB)

Abstract

Objective: To describe unusual manifestation of dengue virus infection that has been increasing in number and elucidate the indirect effect of dengue infection on the central nervous system which may explain the occurence of dengue encephalopathy. Methods: A case report of 6-year-old boy who was admitted with a history of fever for three days, accompanied with decreased consciousness, hypertension, and edema is presented. Laboratory examination showed hemoconcentration, thrombocytopenia, with positive anti dengue Immunoglobulin G (IgG) and IgM, microscopic glomerular hematuria, and proteinuria as well as normal creatinine serum level. He was treated with supportive treatment. Results: After six days, the consciousness was improved and blood pressure was normal.  Proteinuia was alleviated by Day 11 and completely negative on Day 19.  Microscopic glomerular hematuria was negative after 6 months.Conclusions: Recognition of unusual dengue manifestations is important in early diagnosis and effective treatment of the disease.Keywords: Dengue virus infection, encephalopathy, nephropathy DOI: 10.15850/ijihs.v1n1.108
Co-Authors Ahmedz Widiasta Anggraini Alam, Anggraini Bagaskara, Danang Pangestu Gusti Dany Hilmanto Febrianti, Sindy Amalia Fenny Dwiyatnaningrum, Fenny Gizella, Gizella Kurnia Wahyudi, Kurnia Mohamad Yanuar Anggara Muhammad Ilman, Muhammad Nanan Sekarwana Oktorina, Lenny Paramita Diah Winarni Perinandika, Tovan Permadi, Suci Saptyuni Rahadi, Raden Aswin Renarti, Lelani Sidik Utoro Yudi Feriandi