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All Journal JOPS (Journal Of Pharmacy and Science) JPK: Jurnal Proteksi Kesehatan Jurnal Farmasi Tinctura Borneo Journal of Pharmacy
Dini Mardhiyani
universitas abdurrab
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Antibacterial Activity Test Of Leaves Bidara (Ziziphus mauritiana Lam) Ethanolic Extracts Against Staphylococcus aureus Dini Mardhiyani; Moni Afriani
JURNAL PROTEKSI KESEHATAN Vol 10 No 1 (2021): JPK: Jurnal Proteksi Kesehatan
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v10i1.343

Abstract

Infection is the most common ilnness in public. One of the triggers of infection is bacteria. Bidara leaf (Ziziphus mauritiana L) is a plant that has antibacterial compounds is phenolics, saponins and triterpenoids/steroids. The study aims to test antibacterial potency Staphylococcus. antibacterial activity testing was carried out using paper disc difussion methode, the etanol extract show antibacterial activity against Staphylococcus Aureus which is characterized by the presence of clear zone on the media. The results of ethanol extract of bidara leaves with concentrations of 30%, 50% and 70% against Staphylococcus aureus bacteria, the average diameter of inhibitory zones respectively were 8,39 mm, 10,64 mm and 12 mm with the positive control diameter of inhibition zone was 23,46 mm, the negative control diameter of inhibition zone was 0 mm.
PERBANDINGAN KADAR VITAMIN C PADA NANAS SEGAR DAN KERIPIK NENAS DENGAN METODE SPEKTROFOTOMETRI UV-VIS Azlaini Yus Nasution; Dini Mardhiyani; Kony Putriani; Dhea Ananda; Virgiawan Saputro
JURNAL FARMASI DAN MAKANAN Vol 3 No 1 (2019): Journal Of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v3i1.1067

Abstract

Nanas merupakan salah satu buah yang mengandung vitamin C. Vitamin C merupakan senyawa kompleks yang sangat dibutuhkan oleh tubuh yang berfungsi untuk membantu pengaturan atau proses metabolisme tubuh. Di Desa Kualu Nanas, Kampar, nanas diolah menjadi keripik nanas. Tujuan dari penelitian ini adalah untuk mengetahui perbandingan kadar vitamin C yang ada pada nanas segar dan keripik nanas dengan menggunakan spketrofotometri Uv-Vis dengan panjang gelombang 265 nm. Hasil penelitian ini adalah pada uji linearitas didapatkan persamaan regresi linear yaitu y = 0,0809x – 0,1239. Dari persamaan regresi tersebut didapatkan kadar rata-rata nanas segar yaitu 4,274 ppm dan keripik nanas mendapatkan kadar rata-rata yaitu 2,760 ppm.
Formulasi Masker Gel Peel-Off Ekstrak Daun Bidara (Ziziphus Spina-Christi L.) dan Biji Chia (Salvia Hispanica) Sebagai Antioksidan Dini Mardhiyani
Tinctura Vol 3 No 2 (2022): Jurnal Farmasi Tinctura
Publisher : Program Studi S1 Farmasi Fakultas Ilmu Kesehatan Universitas Ibrahimy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35316/tinctura.v3i2.1898

Abstract

Masker gel peel-off salah satu alternatif sediaan yang memiliki kelebihan dari segi kenyamanan dalam penggunaan dan peningkatan aktivitas antioksidan dengan adanya pengaruh penggunaan basis masker gel peel-off, yaitu polivinylalkohol (PVA). Tujuan penelitian ini untuk menguji aktivitas antioksidan ekstrak daun bidara dan biji chia, memformulasikan dan mengevaluasi masker gel peel-off. Tahap formulasi masker gel peel off melalui tahap ekstraksi, uji aktivitas antioksidan, formulasi dan evaluasi. Ektraksi daun bidara dan biji chia dilakukan secara maserasi dan pengukuran antioksidan dengan metode peredaman DPPH diperoleh nilai IC50 sebesar 263,2107 ppm untuk daun bidara dan 227,6850 ppm untuk biji chia. Makser gel pell off dijadikan beberapa variasi konsentrasi ekstrak. Formulasi 0 yaitu hanya basis tanpa ekstrak, Formula I yaitu 5% ekstrak daun bidara dan 1% ekstrak biji chia, formula II yaitu 10% ekstrak daun bidara dan 2% ekstrak biji chia, dan Formulas III yaitu 15% ekstrak daun bidara dan 4% ekstrak biji chia. Formulasi terbaik dari sediaan masker gel peel-off adalah formulasi I dilihat dari hasil uji evaluasi sediaan yang meliputi uji organoleptis, uji homogenitas, uji daya sebar,uji pH, uji viskositas,dan uji waktu sediaan mongering.
Formulation and Antibacterial Activity of Liquid Soap Containing Ketapang (Terminalia catappa L.) Leaves Extract Asiska Permata Dewi; Dini Mardhiyani
Borneo Journal of Pharmacy Vol. 4 No. 1 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i1.1589

Abstract

Ketapang (Terminalia catappa L.) is traditionally used by the community to treat the skin's infections caused by bacteria or fungi. In this study, T. catappa leaves extract was added to the liquid soap formula as an antibacterial. The purpose of this study was to determine the secondary metabolite compounds contained in T. catappa leaves extract, physical evaluation of the preparation, and antibacterial activity of liquid soap. Liquid soap formula was made with various concentrations of T. catappa leaves extract F0 (0%), F1 (1%), F2 (2%), and F3 (3%). The resulting soap was evaluated for organoleptic, pH, high foam, homogeneity, irritation, and its activity against Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia coli using the disc diffusion method. The results showed that the T. catappa leaves extract contained flavonoids, tannins, saponins, and triterpenoids. The liquid soap formula F0 was clear, while F1, F2, and F3 had the characteristics of brown-dark brown, homogeneous, pH between 4.6-5.2, foam stability between 67-72%, which was not significantly different and stable after five minutes of testing, and it did not irritate the skin. Terminalia catappa leaves extracts liquid soap has antibacterial activity at a concentration of 1%, 2%, and 3%, with the largest inhibition zone diameter produced by S. aureus.
Co-Authors Asiska Permata Dewi Dhea Ananda Kony Putriani Moni Afriani Nasution, Azlaini Yus Virgiawan Saputro