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All Journal Health and Medical Journal Nusantara Hasana Journal Ophthalmologica Indonesiana
Naima Lassie
Universitas Baiturrahmah
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Visual Outcome after Oral versus Intravenous Methylpredisolone Therapy for Bilateral Optic Neuritis in Adults Naima Lassie; Hartono Hartono
Health and Medical Journal Vol 2, No 1 (2020): HEME January 2020
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (744.61 KB) | DOI: 10.33854/heme.v2i1.260

Abstract

Introduction: Bilateral optic neuritis in adults is rarer then unilateral optic neuritis. The purpose of this study was to know the clinical profile and to know the visual outcome of bilateral optic neuritis in adult patients after oral versus intravenous methylprednisolone therapy. Methods: A retrospective review of patients with bilateral optic neuritis referred to dr.Sardjito General Hospital, Yogyakarta from 2011-2014. The data consisted of bilateral optic neuritis, unassociated with other pathologic processes. There are two groups of patients: Group A taking oral methylprednisolone 1mg/kgBB and Group B received intravenous methylprednisolone (as ONTT guideline). Visual acuity, visual field with Goldmann Perimetry, RAPD (Relative Afferent Puppilary Defect), Ishihara test and direct ophthalmoscopy evaluation were recorded and analysed in both group at baseline, 1 week, 1 month and 3 months follow up.  Results: Nineteen women and 9 men, with age range of 18-54 years old, had bilateral optic neuritis. The majority of the patients suffered from retrobulbar neuritis (43%), papilitis (39%) and neuroretinitis (18%). The average visual acuity before treatment in Group A was 0.22 ± 0.29 and in Group B had poorer average visual acuity 0.03±0.04 (p>0.05). But the trend of visual recovery in Group B with visual acuity at baseline worsen, the recovery of visual acuity was faster and better at one week. After one month the visual acuity was comparable in both groups (p>0.05). Conclusions: Visual improvement in early period of adult bilateral optic neuritis was similar after oral and intravenous methylprednisolone therapy. 
HUBUNGAN KEHAMILAN TIDAK DIINGINKAN DENGAN KEJADIAN STUNTING PADA ANAK USIA 0-5 TAHUN DI INDONESIA (ANALISIS DATA RISKESDAS 2013) Annisa Lidra Maribeth; Naima Lassie; Yuni Handayani Gusmira
Nusantara Hasana Journal Vol. 2 No. 3 (2022): Nusantara Hasana Journal, August 2022
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v2i3.991

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Indonesia has become 5th top country with biggest stunting rate in the world. Unintended pregnancies can be one of the factors that may play a major role in causing the incidence of stunting in children aged 0-5 years. This study aims to analyze the relationship of unintended pregnancies with incidence of stunting in children aged 0-5 years. This quantitative research used secondary data from National Health Research (Riskesdas) with cross sectional research methods. This research covered all provinces and districts / cities in Indonesia which were carried out from preparation to further analysis in January 2012 - December 2014 and the secondary data was processed in 2019. The sample of this study was women aged 15-49 years old with children 0-5 years old in Indonesia which amount to 42,684 people. Results: In bivariate analysis using chi-square test, it was found that the relationship of unintended pregnancies with stunting have a p value of 0.04 (OR: 1.059 and 95% CI: 1.003-1.118). In multivariate test using logistic regression tests, the relationship of unintended pregnancies became insignificant to stunting with p-value 0, 077 (OR: 1.051; 95% CI: 0.995-1,110). There are two confounding variabels, economic status and education related significantly to stunting with p value <0.001. Conclusion: in multivariate analysis there was no relathionship of unintended pregnancy with stunting in children under five years old ( p value> 0.05). There is confounding in this study, the educational variable and economic status are confounding variable. Education and economic status have a significant relationship on multivariate analysis (p value< 0.001) with stunting.
Progesterone Receptor Expression in Histopathological Subtypes of Beningn Orbitocranial Meningiomas Naima Lassie; Agus Supartoto
Majalah Oftalmologi Indonesia Vol 42 No 1 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i1.72

Abstract

Background: Meningioma is the most common benign brain tumor which has several subtypes histopathologically.Previous studies indicate that progesterone receptors (PR) plays important role in thetumor behavior and may determine its prognosis. However, whether different subtypes show similarPR expression remains unclear. This study aimed to evaluate PR expression, in many histopathologicalsubtypes of benign orbitocranial meningiomas.Methods: Eighty one patients visiting Sardjito General Hospital with benign orbitorcranial meningioma(WHO grade I) between 2010-2013 were included. Tumor specimens were obtained for histopathologyassessment and PR expression using immunohistochemistry examination, including the intensity ofexpression.Results: There were 72 (88.9%) women and 9 (22.2%) men, aged between 21-72 years old. PR waspositive in 71.6% patients (76.4% women). There were different subtypes of meningioma as follows:meningotheliomatous (44.4%), transitional (33.3%), and fibrous (14.8%). PR was positive in 72.2%meningotheliomatous, 70.4% in transitional, and 66.7% fibrous subtype. Other subtypes of benignmeningioma (microcystic, angiomatous, lymphoplamocyte-rich, and metaplastic) were not found inour study. But, this finding was not statistically significant using Pearson correlation test (p>0.05).Conclusion: The majority of patients with meningioma were women. The most common histopathologicalsubtypes were meningotheliomatous and transitional, of which more than 70% was PR positive.However, there were very little variations in PR expression among different subtypes of benign orbitocranialmeningioma. Keywords: orbitocranial meningioma, progesterone receptor (PR) expression, histopathological subtype
Co-Authors Agus Supartoto Annisa Lidra Maribeth Eko Perdana Putra Hartono Hartono Irma Primawati Yuni Handayani Gusmira