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ANALISIS SENYAWA BERBAHAYA PARFUM ISI ULANG YANG DIJUAL DI KOTA PADANG MENGGUNAKAN METODE KROMATROGRAFI GAS-SPEKTROMETRI MASSA Ridho Asra; R. Rusdi; Putut Arifin; N. Nessa
Jurnal Riset Kimia Vol. 10 No. 1 (2019): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v12i2.324

Abstract

Perfume is widely used by most of people in this world. The increasing demand of perfume has caused many producers cheating by adding dangerous compounds and also unregistered by the National Agency of Drug and Food Control Indonesia. The aim of this study is to analyze the dangerous compounds in unregistered perfumes sold in Pasar Raya Padang City by using gas chromatography-mass spectrometry (GC-MS) method. In this Study, samples (A, B, C, D and E) were collected and the value of specific weight and refractive index of the samples were analyzed. The results showed that five samples contained relatively similar chemical compounds. Twelve compounds were detected and seven of them were harmful to health in refill perfumes which were dipropylene glycol, linalool, lily aldehyde, benzenepentanol, dimethylbenzyl carbinyl acetate, dihydro methyl jasmonate, alpha hexyl cinnamic aldehyde, based on Material Safety Data Sheet (MSDS). Regular monitoring of chemicals used in the manufacture of perfumes which may cause health risks to users should be controlled by National Agency of Drug and Food Control Indonesia.
Pengaplikasian Cangkang Telur Dan Karbon Aktif Sebagai Adsorben Logam Timbal Sestry Misfadhila; Zikra Azizah; Rusdi Rusdi; Chyntia Diane Putri
Jurnal Farmasi Higea Vol 10, No 2 (2018)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (502.377 KB) | DOI: 10.52689/higea.v10i2.187

Abstract

Perbandingan Akrilamidakopi Bubuk Tradisional Dan Luwak Dengan Metode HPLC Ridho Asra; Rusdi Rusdi; Sofia Nofianti; Nessa Nessa
Jurnal Katalisator Vol 4, No 2 (2019): KATALISATOR
Publisher : LLDIKTI Wilayah X

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22216/jk.v4i2.4644

Abstract

Akrilamida merupakan senyawa kimia terdapat pada kopi yang disangrai pada suhu diatas 120 ˚C, berpotensi menyebabkan kanker pada manusia. Tujuan dari penelitian ini adalah untuk membandingkan kandungan akrilamida dalam kopi bubuk tradisional dan kopi  luwak dengan metode Kromatografi Cair Kinerja Tinggi.  Fase gerak yang digunakan asetonitril: aquabidest (15: 85, v/v), dengan detektor Photodioday-Array (PDA) pada ℷ   200 nm. Akrilamida dalam sampel kopi bubuk teridentifikasi pada waktu retensi (tR) ± 6,8 menit. Metode ini terbukti valid dengan linearitas y = 356468 + 293761 x, koefisien korelasi (r) = 0,9993, batas deteksi 1,9901 µg/mL dan batas kuantitasi 6,6337 µg/mL, presisi dengan % SBR = 0,207 %, akurasi dengan % perolehan kembali kopi bubuk tradisional dan kopi bubuk luwak 99 % dan 104 %. Kadar akrilamida dalam sampel kopi bubuk 1 sampai 6 berturut-turut adalah 1115 ± 12,17 µg/g sampel (1), 687 ± 7,58  µg/g sampel (2), 1461 ± 63,89 µg/g sampel (3), 221 ± 3,54 µg/g sampel (4), 128 ± 3,24 µg/g sampel (5), 195 ± 1 µg/g sampel (6). Dari keenam sampel kopi bubuk menunjukkan bahwa kadar akrilamida masing-masing sampel berkisar antara 128 sampai 1461 µg/g. Kadar yang diperoleh melebihi batas aman konsumsi akrilamida yang dikeluarkan oleh WHOAcrylamide is a chemical compound found in roasted coffee at temperatures above 120 ˚C which can potentially cause cancer in humans. The purpose of this research was to analyze acrylamide contents in traditional ground coffee and civet ground coffee by using High Performance Liquid Chromatography (HPLC) method. This analysis was carried out by isocratic elution system, the mobile phase of acetonitrile : aquabidest (15 : 85, v/v), using the stationary phase of the Shimadzu Shimpack ODS C18 column (250 × 4.6 mm), flow rate of 0.5 mL/minute, injection volume 20 µL, with a Photodioday-Array (PDA) detector at a wavelength of 200 nm. Acrylamide in ground coffee samples was identified at retention time (tR) ± 6.8 minutes. This method is proved valid with the linearity y = 356468 + 293761 x, correlation coefficient (r) = 0.9993, limit of detection 1.9901 µg / mL and limit of quantitation 6.6337 µg / mL, precision with % RSD = 0.207 %, acuracy with % recovery of traditional ground coffee and luwak ground coffee 99 % and 104 %. Acrylamide levels in 1 to 6 ground coffee samples in a row is 1115 ± 12.17 µg / g samples (1), 687 ± 7.58 µg / g samples (2), 1461 ± 63.89 µg / g samples (3), 221 ± 3.54 µg / g sample (4), 128 ± 3.24 µg / g sample (5), 195 ± 1 µg / g sample (6). Of the six ground coffee samples showed that the acrylamide levels of each sample ranged from 128 to 1461 µg / g. The levels obtained exceed the safe limits of acrylamide consumption released by WHO