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All Journal Majalah Kedokteran Sriwijaya The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Syadra Bardiman Rasyad
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Health Professions Medicine & Pharmacology Nursing Public Health

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Karakteristik Penderita Kanker Pankreas di Instalasi Rawat Inap RSUP Dr. Mohammad Hoesin Palembang Tahun 2009 - 2013 Auliya Bella Oktarina; Syadra Bardiman Rasyad; Safyudin Safyudin
Majalah Kedokteran Sriwijaya Vol 47, No 1 (2015): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v47i1.2737

Abstract

Kanker dapat menyerang berbagai organ tubuh, termasuk pankreas. Penderita banyak yang terdiagnosis dengan metastasis. Data mengenai karakteristik kanker pankreas di RSUP Dr. Mohammad Hoesin Palembang belum tersedia. Penelitian ini bertujuan untuk mengetahui karakteristik penderita kanker pankreas di Instalasi Rawat Inap RSUP Dr. Mohammad Hoesin Palembang tahun 2009-2013.  Penelitian ini merupakan survei deskriptif. Penderita kanker pankreas di Instalasi Rawat Inap RSUP Dr. Mohammad Hoesin Palembang tahun 2009-2013 berjumlah 78 orang. Data dikumpulkan dari catatan rekam medis seluruh penderita kanker pankreas di Instalasi Rawat Inap RSUP Dr. Mohammad Hoesin Palembang tahun 2009-2013 diperoleh 43 subjek penelitian. Dari penelitian ini didapatkan, 2,33% penderita kanker pankreas berusia 20-34 tahun, 16,28% berusia 35-44 tahun, 25,58% berusia 45-54 tahun, 39,53% berusia 55-64 tahun, 13,95% berusia 65-74 tahun, 2,33% berusia 75-84 tahun. Mayoritas (67,44%) penderita adalah laki-laki dan 32,56% adalah perempuan. Penderita yang mengalami nyeri abdomen adalah 90,70%, 65,12% ikterus, dan 27,91% berat badan menurun. Penderita yang memiliki kadar bilirubin total lebih dari normal adalah 83,33%, 88,89% bilirubin direk lebih dari normal, 63,89% bilirubin indirek lebih dari normal, 72,5% AST lebih dari normal, 70% ALT lebih dari normal, 89,66% ALP lebih dari normal, 83,33% GGT lebih dari normal, 70,73% albumin kurang dari normal, 50% CEA lebih dari normal, 76,92% CA 19-9 lebih dari normal. Berdasarkan perluasan tumor, 18,60% tumor hanya pada pankreas, 27,91% meluas ke bagian sekitar, 30,23% metastasis, 23,26% tidak diketahui. Penderita kanker pankreas paling banyak berusia 55-64 tahun dan lebih banyak laki-laki. Manifestasi klinis yang paling banyak adalah nyeri abdomen. Sebagian besar hasil laboratorium penderita diluar kisaran normal. Lokasi tumor paling banyak adalah pada caput pankreas. Berdasarkan perluasan tumor, penderita paling banyak mengalami metastasis.
The Efficacy of Trimethoprim-sulfamethoxazole Compared to Ciprofloxacin in The Treatment of Spontaneous Bacterial Peritonitis in Cirrhotic Patients with Ascites Syadra Bardiman Rasyad; Ahmar Kurniadi; Fuad Bakry Fauzi
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 3, NUMBER 3, December 2002
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/33200276-81

Abstract

Background: The incidence of spontaneous bacterial peritonitis (SBP) is 7 to 23%, and the associated mortality rate is 25 to 40% (Rimola 1992). The aim of this study was to evaluate the efficacy of trimethoprim-sulfamethoxazole compared to ciprofloxacin in the treatment of SBP in cirrhotic patients with ascites. Materials and Method: This prospective randomized double blind study included 43 cirrhotic patients with ascites (25 males, 18 females, ages 23-75 years, one female patient died prior to laboratory evaluation) enrolled between May 1999 and June 2000, at the Department of Internal Medicine of Mohammad Hoesin General Hospital /the Medical Faculty of Sriwijaya University of Palembang, South Sumatera. Twenty-three patients (53.4%) with SBP were eligible for the study, all were randomized. Patients were divided into 2 groups (13 in group I, and 10 in group II), those receiving trimethoprim- sulfamethoxazole 960 mg once daily for 10 days and those receiving ciprofloxacin 1000 mg once daily for 10 days. Statistically, there was no significant difference in the characteristics of the 2 groups.  Results: The incidence of SBP in our study was 53.4% (23 patients out of 43 cirrhotic patients with ascites). The Results of the study demonstrate that trimethoprim-sulfamethoxazole and ciprofloxacin are both effective (91.6% and 90%) in the treatment of SBP. There was a significant decrease in ascitic fluid PMN count after 10 days treatment with both of the drugs (p=0.001 and p=0.000). There was no statistically significant difference (t-test) between the two groups in decreasing the ascitic fluid PMN count after the treatment (p=0.664). Conclusion: Trimethoprim-sulfamethoxazole and ciprofloxacin has similar efficacy in the treatment of spontaneous bacterial peritonitis in cirrhotic patients with ascites.    Keyword: Trimethoprim-sulfamethoxazole, ciprofloxacin, spontaneous bacterial peritonitis.
Colonoscopic Findings in Patients with Chronic Diarrhea at Mohammad Hoesin Hospital Palembang Imam Supriyanto; Suyata Suyata; Syadra Bardiman Rasyad; Fuad Bakry
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 14, NUMBER 2, August 2013
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (413.499 KB) | DOI: 10.24871/142201381-84

Abstract

Background: Chronic diarrhea is a common problem encountered by clinicians. Colonoscopy is a tool with high accuracy and sensitivity to depict abnormalities and has the advantage in distinguishing the abnormalities that cause chronic diarrhea. Nevertheless, the colonoscopic findings in patients with chronic diarrhea vary by age. The objective of this study is to observe abnormalities found in lower gastrointestinal tract in patients withchronic diarrhea who underwent colonoscopy and its relationship with age.Method: An observational analytic study, data retrieved from medical record of outpatient and inpatient with chronic diarrhea at Mohammad Hoesin Hospital Palembang from January 2011 until December 2012. Chronic diarrhea diagnosis was based on clinical findings, laboratory result, and colonoscopy procedure. Patients were then divided into groups based on age ( 40 and 40). Data were analyzed with SPSS 12.0.Results: There were 92 patients consisted of 56 (60.9%) male and 36 (39.1%) female. Mean age was 47.67 ± 16.83 with age interval 15-85 years. Group I of 35 (38%) patients, whereas group II of 57 (62%) patients. The colonoscopic findings were ulcerative colitis 33 (35.9%), normal 27 (29.3%), colon tumor 20 (21.7%), colitis tuberculosis 5 (5.4%), Crohn’s disease 3 (3.3%) and polyp 4 (4.3%). Based on age, the incidence of ulcerative colitis was most frequently encountered in both groups, whereas normal colon and colon tumors were encountered most in group II. No correlation was found between age and colon abnormality (p = 0.87).Conclusion: The most common finding was ulcerative colitis followed by normal colon and colon tumor. There was no correlation between age and colon abnormalities.Keywords: chronic diarrhea, colonoscopy, age
Correlation between Aspartate Aminotransferase to Platelet Ratio Index Score and the Degree of Esophageal Varices with Liver Cirrhosis Imam Supriyanto; Suyata Suyata; Syadra Bardiman Rasyad; Fuad Bakry
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 13, NUMBER 3, Desember 2012
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (417.157 KB) | DOI: 10.24871/1332012141-144

Abstract

ABSTRACTBackground: Esophageal varices is the most common complication in liver cirrhosis. Bleeding varices is a serious complication causing increased mortality rate. In anticipation of those complications, the role of screening test is essential. Endoscopy is the standard method for assessing esophageal varices, but it carries certain risks for patients if it is contraindicated. Moreover, it is an invasive, expensive and uncomfortable procedure. Accordingly, a non-invasive method, aspartat aminotransferase to platelet ratio index (APRI) score, has been developed for evaluating esophageal varices.  Method: An analytic cross-sectional observational study was conducted in patients with liver cirrhosis who underwent endoscopy between March 2011 and August 2012. Data were obtained from medical records of hospitalized patients in Mohammad Hoesin General Hospital. The degree of esophageal varices was assessed based on endoscopic findings and APRI score. Spearman test was performed to analyze the correlation between APRI score and the degree of esophageal varices.Results: There were 55 patients, 30 (54.5%) male and 25 (45.5%) female patients, with a range of age between 15-70 years and a mean value of age of 47.09 ± 12.8. APRI score 0.5 was found in 21.81% subjects, APRI score of 0.5-1.5 was obtained in 41.81% subjects and APRI score 1.5 was noted in 36.36% subjects with a mean value of 2.32 ± 3.92. There was a correlation between APRI score and degree of esophageal varices with p = 0.011 Conclusion: APRI score can indirectly predict esophageal varices in patients with liver cirrhosis. Keywords: APRI score, the degree of esophageal varices, liver cirrhosis
Co-Authors Ahmar Kurniadi Auliya Bella Oktarina Fuad Bakry Fuad Bakry Fauzi Imam Supriyanto Safyudin Suyata Suyata Suyata Suyata