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All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Teknik Sipil Cendekia (JTSC) Bioscientia Medicina : Journal of Biomedicine and Translational Research Geoplanart

Setiawan, Felix

Teknik Sipil Universitas Winaya Mukti

Author-ID : 3597202

Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Education Environmental Science Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Social Sciences Transportation

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AUDIT STRUKTUR GEDUNG BANK X KOTA BANJARMASIN Syapril Janizar; Felix Setiawan; Denah Harun Saputra
JURNAL TEKNIK SIPIL CENDEKIA (JTSC) Vol 1 No 1 (2020): Juli
Publisher : Faculty of Engineering, Planning and Architecture, Winaya Mukti University

This study aims to ensure that the existing conditions of the structure of the Bank X Building inBanjarmasin City are still able to withstand the burden that occurs and can meet the service periodproperly in accordance with applicable regulatory standards. In this study, structural inspection isdescribed structural inspection, starting from visual inspection, undestructive inspection of buildingstructures by testing the compressive strength of concrete using a Hammer Test, testing the number ofreinforcement, reinforcement distance and a concrete blanket using the Rebar Locator / Cover Meterand verticality checking / building rigidity. In addition, the results of the examination of the structure ofthe building were analyzed by modeling the existing building structure elements using tools or structuralanalysis software. The final result of this study is to provide recommendations for structuralimprovement in accordance with the level of damage that occurs.

PEMERIKSAAN KELAIKAN FUNGSI BANGUNAN GEDUNG RUMAH SAKIT Syapril Janizar; Felix Setiawan; Edi Kurniawan
JURNAL TEKNIK SIPIL CENDEKIA (JTSC) Vol 1 No 1 (2020): Juli
Publisher : Faculty of Engineering, Planning and Architecture, Winaya Mukti University

Laik Fungsi adalah suatu kondisi Bangunan Gedung yang memenuhi persyaratan administratif danpersyaratan teknis sesuai dengan fungsi Bangunan Gedung yang ditetapkan. Pemeriksaaankelaikan fungsi bangunan gedung dilakukan berdasarkan lima komponen persyaratan : tatabangunan, keselamatan, kesehatan, kenyamanan, kemudahan. Kelaikan fungsi suatu bangunangedung di nilai berdasarkan persyaratan administrasi dan persyaratan teknis bangunan gedung.Metode dalam penilaian menggunakan metode skala likert dan metode Analytic Hierarchy Process(AHP). Pembobotan untuk persyaratan tata bangunan gedung yaitu tidak laik 0 % - 33,33%, laikdengan perbaikan 33,34% - 66,66% dan laik 66,67%-100% sedangkan untuk pembobotankeselamatan 43%, kesehatan 28%, kenyamanan 25% dan kemudahan 4%.

PERCEPATAN JADWAL KONSTRUKSI DAN PENGARUHNYA TERHADAP BIAYA PENYELESAIAN PROYEK KONSTRUKSI Felix Setiawan; Syapril Janizar
JURNAL TEKNIK SIPIL CENDEKIA (JTSC) Vol 2 No 1 (2021): February
Publisher : Faculty of Engineering, Planning and Architecture, Winaya Mukti University

Sarana transportasi saat ini sangat penting untuk terus dibangun secara efektif dan efisien agar tingkat kelancaran dan ketepatan waktu menuju tujuan lebih mudah dan cepat serta untuk memenuhi standar pelayanan minimal dari jalan tol. Sejalan dengan itu maka agar jalan tol tetap dalam standar pelayanan minimal perlu dilakukan penambahan kapasitas jalan secara efektif dan efisien untuk itu maka perlu dilakukan pengkajian apakah dapat dilakukan percepatan proyek penambahan kapasitas jalan, agar tingkat standar pelayanan minimal dapat terus dipertahankan dan sejauh manakah pengaruh percepatan jadwal proyek terhadap biaya pembangunan.Salah satu metoda yang dapat digunakan untuk menganalisis pengaruh percepatan proyek terhadap biaya yang harus dikeluarkan adalah dengan analisis pertukaran biaya dan waktu (time cost trade off).Variabel – variabel yang dipakai dalam perhitungan “Percepatan Jadwal Konstruksi dan Pengaruhnya Terhadap Biaya Penyelesaian Proyek Konstruksi” adalah pekerja langsung, peralatan, Jam kerja lembur, metode kontruksi, semuanya memiliki pengaruh terhadap biaya yang berbeda-beda, percepatan (crash) atau kompresi waktu yang dilakukan pada pekerjaan yang mempunyai biaya terbesar dan yang mempunyai hubungan dengan pekerjaan yang memiliki biaya terbesar, keuntungan yang didapat jika jalan tol dibuka terlebih dahulu akibat dari percepatan proyek lebih kecil jika dibandingkan dengan biaya yang dibutuhkan untuk melakukan percepatan proyek konstruksi pada proyek ini jika ditinjau dari segi biaya maka percepatan tidak perlu dilakukan karena biaya untuk melakukan percepatan lebih besar jika dibandingkan dengan keuntungan yang didapat.

PERENCANAAN JEMBATAN CABLE STAYED 200 METER (Studi Kasus : Jembatan Cijambe Garut) Syapril Janizar; Habdullah Habdullah; Felix Setiawan; Lucky Ampearawan Schipper
JURNAL TEKNIK SIPIL CENDEKIA (JTSC) Vol 3 No 1 (2022): Februari
Publisher : Faculty of Engineering, Planning and Architecture, Winaya Mukti University

In this final project, we discuss the Planning of a Cable Stayed Bridge with a Length of 200 meters. This bridge has a length of 200 meters with a span of 180 meters and an edge span of 20 meters. The bridge cable configuration uses a semi harp pattern with a two planes system cable position. The bridge has a vehicle floor width of 6.00 meters, and a sidewalk of 1.5 meters right and left. As for the results of this design, the secondary structure of the bridge consists of railings with a hollow steel profile with a diameter of 60.5, curbs with a thickness of 250 mm, a vehicle floor plate with a thickness of 200 mm concrete slab and 50 mm asphalt, and a girder consisting of a WF 1300,550 transverse girder. 28.34, longitudinal girder WF 600.200.11.17, and cantilever girder WF 300.150.6.5.9 for the connection of the girder itself using a simple connection with an L elbow plate. While the main structure consists of the main girder using rectangular twin box girders with dimensions of 2500.1500.50.50, then stay cable is made up of 7 – wire strands with a diameter of 15.2 mm and a pylon which is designed using reinforced concrete material with dimensions of 4000 mm x 3000 mm with a cavity inside.

Perkiraan Waktu Dalam Penyelesaian Proyek Kolam Retensi Sirnaraga Menggunakan Penerapan EVA (Earned Value Analysis) Syapril Janizar; Felix Setiawan; Rina Rahmawati
GEOPLANART Vol 3, No 2 (2021): EDISI MEI
Publisher : Universitas Winaya Mukti

Kolam Retensi adalah suatu kolam yang dapat menampung atau meresap air sementara yang terdapat didalamnya, tentunya dalam pelaksanaan kontruksinya harus direncanakan penjadwalan yang matang. Metode “Nilai Hasil” (Earned Value) merupakan suatu metode pengendalian yang digunakan untuk mengendalikan biaya dan jadwal proyek secara terpadu. Metode ini dapat memberikan informasi dalam status kinerja proyek pada suatu periode pelaporan dan memberikan informasi prediksi biaya yang dibutuhkan serta waktu untuk menyelesaikan seluruh pekerjaan berdasarkan indikator kinerja saat pelaporan. Dalam penelitian ini dicoba menhitung perkiraan waktu dalam penyelesaian proyek dengan menggunakan metode tersebut agar diharapkan mendapatkan penjadwalan konstruksi yang efisien.

PENGENDALIAN WAKTU PELAKSANAAN PROJECT DENGAN MENGGUNAKAN EARNED VALUE CONCEPT Felix Setiawan; Maulana Ihsan
JURNAL TEKNIK SIPIL CENDEKIA (JTSC) Vol 4 No 1 (2023): February
Publisher : Departement of Civil Engineering, Universitas Winaya Mukti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51988/jtsc.v4i1.125

The success of a project is a series of activities that include the stages of planning, implementation and supervision, so that the goals that have been set can be achieved and implemented. Therefore, it is necessary to carry out supervision and control measures in various sectors, especially time control. The method used in this study is the Earn Value Concept method. This research was conducted, with the aim of knowing the performance of the project, problems occurring and solutions to these problems. The data used are in the form of an S curve, RAB, and weekly progress reports. From these data obtained the results of BCWS and BCWP, with the help of Microsoft Excel programs set SV, SPI values, as well as predicting the final time of the project (ETC and EAC).

ANALISIS EFEKTIVITAS PENGGUNAAN ALAT BERAT PADA SUATU PROYEK KONSTRUKSI (Studi Kasus : Pembangunan Kolam Retensi Wilayah Sirnaraga – Kota Bandung) Syapril Janizar; Aldy Ardianto; Felix Setiawan
JURNAL TEKNIK SIPIL CENDEKIA (JTSC) Vol 4 No 2 (2023): July
Publisher : Departement of Civil Engineering, Universitas Winaya Mukti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51988/jtsc.v4i2.151

This research is motivated by the need to observe and analyze the efficiency of using heavy equipment in the retention pond construction project in the Sirnaraga area. The purpose of this study was to determine the production capacity of heavy equipment used, the efficiency factor of heavy equipment and to analyze the effect of the efficiency factor on the production capacity of heavy equipment. The method used in this research is descriptive analytic method which focuses on solving actual problems, where the data collected, compiled, explained and analyzed. The results showed that the production capacity of heavy equipment for excavators was 52.14 m3/hour, dump truck was 11.60 m3/hour, stamper was 540.00 m3/hour, vibrator concrete was 750 m3/hour, portable concrete mixer pump was 83 m3/hour, and hydraulic truck crane of 10.384 tons/hour; efficiency factor of heavy equipment for excavator is 0.83 (good operating condition), dump truck is 0.80 (medium), stamper is 0.81 (good), vibrator concrete is 0.83 (good), portable concrete mixer pump is 0.83 (good), and hydraulic truck crane 0.83 (good); The greater the production capacity of each unit of heavy equipment, the higher the efficiency factor of the heavy equipment obtained with good operating conditions. Vice versa, if the production capacity is small, the efficiency factor value of the heavy equipment used will also be small.

Whey Protein as an Adjuvant Therapy for Wound Healing and Infection Control: A Systematic Review and Meta-Analysis of Clinical and Preclinical Evidence Aliva Nabila Farinisa; Niken Puruhita; Yan Wisnu Prajoko; Felix Setiawan
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 10 No. 1 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v10i1.1483

Background: Impaired wound healing and subsequent infections represent a significant clinical and economic burden. Nutritional status, particularly high-quality protein provision, is a critical, modifiable determinant of healing outcomes. Whey protein (WP), a rich source of essential amino acids and unique bioactive components, has emerged as a promising adjuvant therapy. Methods: We conducted a systematic review and meta-analysis adhering to PRISMA guidelines. We searched PubMed, Scopus, and Web of Science from January 2015 to December 2024 for clinical randomized controlled trials (RCTs) and preclinical controlled studies evaluating WP supplementation on wound healing and infection. Rigorous inclusion criteria led to the selection of seven studies (four clinical RCTs, three preclinical) for quantitative synthesis. Data were pooled using a random-effects model to calculate Standardized Mean Differences (SMD) for continuous outcomes and Odds Ratios (OR) for dichotomous outcomes. Results: The meta-analysis of four clinical RCTs (n=340 patients) demonstrated that WP supplementation significantly accelerated wound healing (SMD = 0.78; 95% CI 0.45, 1.11; p < 0.0001) with moderate heterogeneity (I²=38%). Furthermore, WP significantly reduced the odds of wound infection by 48% (OR = 0.52; 95% CI 0.31, 0.87; p=0.01) with no heterogeneity (I²=0%). Preclinical synthesis (3 studies, n=62 animals) revealed a significant reduction in pro-inflammatory cytokines (TNF-α, IL-6) at the wound site (SMD = -1.15; 95% CI -1.67, -0.63; p < 0.0001). Conclusion: This meta-analysis provides robust quantitative evidence that whey protein functions as an effective adjuvant therapy, significantly enhancing wound repair and providing clinically relevant infection control. These benefits appear to be mediated by a dual mechanism: providing essential anabolic substrates for tissue repair and exerting potent immunomodulatory and antioxidant effects via bioactive components like lactoferrin and cysteine.

Vitamin D in the Breast Cancer Continuum: A Systematic Review and Meta-Analysis of Primary Prevention, Patient Prognosis, and Adjunctive Treatment Response Felix Setiawan; Yan Wisnu Prajoko; Niken Puruhita; Aliva Nabila Farinisa
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 10 No. 1 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v10i1.1486

Background: The role of vitamin D across the breast cancer spectrum remains complex and contested. Compelling preclinical antineoplastic mechanisms contrast with inconsistent clinical findings. Large randomized controlled trials (RCTs) show null effects for primary prevention, while observational studies often link higher vitamin D status at diagnosis with better prognosis. Key conflicts include this prevention-prognosis disconnect, debates over linear versus J-shaped prognostic dose-responses, and a "receptor-status paradox" where estrogen receptor-positive (ER-positive) disease shows prognostic links, but hormone receptor-negative (HR-negative)/triple-negative (TNBC) subtypes derive greater benefit (improved pathological complete response, pCR) from vitamin D intervention during neoadjuvant chemotherapy (NACT). This study systematically synthesizes evidence across these distinct clinical contexts. Methods: Following PRISMA guidelines, we systematically reviewed PubMed, EMBASE, and CENTRAL (January 1st, 2014–September 2nd, 2025) for high-impact RCTs and large prospective cohort studies evaluating vitamin D supplementation or serum 25-hydroxyvitamin D (25(OH)D) levels regarding breast cancer incidence, prognosis (survival/recurrence), or pCR after NACT. Quality was assessed (Cochrane RoB 2; Newcastle-Ottawa Scale). Data were extracted dually. Findings were synthesized stratigraphically (prevention, prognosis, treatment). A random-effects meta-analysis pooled pCR data from NACT RCTs. Results: Six high-quality studies (3 RCTs, 3 cohorts; N=31,026) were included. (1) Prevention: The VITAL RCT (N=25,871; mean baseline 25(OH)D 30.8 ng/mL) found no reduction in incident invasive breast cancer with 2000 IU/day vitamin D3 (HR 1.02, 95% CI 0.79–1.31). (2) Prognosis: Cohort studies (N=4,835) showed higher 25(OH)D linked to better OS (Adj HR T3 vs T1: 0.72). Complexity emerged: one study linked benefit specifically to ER-positive recurrence (Adj HR 0.87), while another reported a J-shaped curve for EFS, with worse outcomes at both low (≤52 nmol/L; Adj HR 1.63) and high (≥99 nmol/L; Adj HR 1.37) levels versus intermediate. (3) Treatment: Meta-analysis of two NACT RCTs (N=310) showed vitamin D supplementation significantly increased pCR rates (38.1% vs 22.6%; Pooled RR 1.69, 95% CI 1.21–2.36; P=0.002; I²=0%). Subgroup data strongly suggested greater benefit in HR-negative/TNBC and baseline-deficient patients. Conclusion: Vitamin D supplementation appears ineffective for primary breast cancer prevention in replete populations. Its prognostic role is complex, suggesting an optimal 25(OH)D range (potentially ~30-40 ng/mL) and possible ER-specific hormonal modulation effects, though causality from observational data remains uncertain. Critically, vitamin D intervention during NACT significantly improves pCR, particularly in HR-negative/TNBC, likely via distinct chemosensitization/immunomodulatory mechanisms. This synthesis provides a framework for understanding these context-dependent roles, supporting vitamin D assessment and potentially adjunctive NACT supplementation, especially in deficient patients with aggressive subtypes, pending necessary validation in larger trials.

PENERAPAN BALOK TIDUR DALAM STRUKTUR BANGUNAN 2 LANTAI Hafudiansyah, Edward; Mussyafa, Faris; Setiawan, Felix; Amperawan Schipper, Lucky; Dwi Hasyti, Yukeu
JURNAL TEKNIK SIPIL CENDEKIA (JTSC) Vol 5 No 1 (2024): February
Publisher : Departement of Civil Engineering, Universitas Winaya Mukti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51988/jtsc.v5i1.194

Gedung Sate is one of the historic buildings that has become an icon in the city of Bandung, has a long history with a distinctive architectural design. Adjustments: The development of a new building that is adapted to the structural conditions of the existing building has experienced several obstacles, one of which is the free space between the basement floor and the beams in one of the building structures in the Gedung Sate area, namely the Setda Building A. This has resulted in the need for more space. So it is planned to use sleeping beam. This research aims to determine whether the planned sleeping beam dimensions still meet the criteria for calculating reinforcement requirements. The research method used is a qualitative research method with a case study type. Structural calculations were carried out with the help of ETABS software based on SNI 2847 2019. Based on the calculation results, the dimensions required for beam planning are B1 700/500 and B2 are 800/550. With the number of B1 reinforcements being 9D19 at the top support and 5D19 at the bottom support and 7D19 at the top field and 11D19 at the bottom field. Meanwhile, reinforcement for B2 is 8D19 at the top support and 6D19 at the bottom support and 6D19 at the top field and 6D19 at the bottom field.

Co-Authors Aldy Ardianto Aliva Nabila Farinisa Amperawan Schipper, Lucky Denah Harun Saputra Edi Kurniawan Habdullah Habdullah Hafudiansyah, Edward Lucky Ampearawan Schipper Maulana Ihsan Mussyafa, Faris Niken Puruhita Rina Rahmawati Schipper, Lucky Amperawan Syapril Janizar Yan Wisnu Prajoko Yukeu Dwi Hasyti

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