Indi Esha
Departemen Pulmonologi Dan Kedokteran Respirasi, Fakultas Kedokteran, Universitas Riau, Riau

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Journal : Respiratory Science

Smoking Cessation: A Review Indi Esha; Riska Yuliana Sari
Respiratory Science Vol. 4 No. 1 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i1.100

Abstract

Smoking is a leading cause of preventable death worldwide. Smoking damages almost all organs and body systems and reduces the overall health of a person with the highest mortality, especially due to respiratory and cardiovascular disease. Evidence shows that the symptoms and prognosis of smoking-related diseases will improve after smoking cessation. Smoking cessation is one of the most important ways to improve the prognosis of patients with respiratory ailments. Counseling and treatment can increase the chances of smokers to successfully smoke cessation. Smoking cessation therapy must include pharmacological treatment (Nicotine Replacement Therapy (NRT), bupropion, varenicline or N-acetylcysteine) combined with nonpharmacological therapy.
Immunopathogenesis of Silicotuberculosis: A Literature Review Indi Esha; Elvando Tunggul Mauliate Simatupang
Respiratory Science Vol. 4 No. 1 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i1.103

Abstract

Silicotuberculosis is a tuberculosis infection that emerges as a silicosis complication. A silicosis patient is 2.8 to 39 times more likely to develop pulmonary tuberculosis (TB). Moreover, the fibrotic condition caused by silicosis may exacerbate the symptoms and worsen the clinical outcome of silicotuberculosis patients.  The current report suggests that the immune system plays an important role in the pathogenesis of this disease. Silicosis or silica exposure might interfere with the immunological response, especially the macrophages, which permit the Mycobacterium tuberculosis to infect the host. In this literature review, we will discuss the definition, epidemiology, and immunopathogenesis of silicotuberculosis.