Indi Esha
Departemen Pulmonologi Dan Kedokteran Respirasi, Fakultas Kedokteran, Universitas Riau, Riau

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Risk Factors Affecting Respiratory Symptoms and Impaired Lung Function of Palm Oil Mill Workers in the District of Kandis Surya Hajar Fitria Dana; Indi Esha; Faisal Yunus; Adrianison Adrianison; Azizman Saad; Ridha Restilla
Jurnal Respirologi Indonesia Vol 41, No 3 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i3.194

Abstract

Background: Air pollution that exposed to human have been a problem all over the world and caused a variety of lung disease. Gases and particles emitted from industry including sulfur oxide, nitrogen oxide, and particulate matter may lead to decreasing lung function. Sulfur dioxide is one of the highest causes of air pollution at the highest level. Workers exposure to gases were vulnerable to respiratory function abnormality. Methods: A study on the effect of risk factors and sulfur dioxide exposure on lung function of palm oil workers in the district of Kandis was carried out in December 2019–January 2020. The research aim at describing sulfur dioxide air ambient in palm oil mill as well as respiratory state of palm oil workers and analyzing sulfur dioxide exposure and lung function relationship. Result: The result showed that sulfur dioxide concentration in outdoor 25.7 µg/Nm3 and indoor 20.6 µg/Nm3. The result of spirometry showed obstruction in 13% of the workers. Breathlessness and productive cough are the most common symptoms. Several factors that correlated with lung function namely as personal protective equipment (p=0.001), length of working (p=0.003), and smoking habit (p=0.004). From multivariate analysis, personal protective equipment has a significant correlation with lung function (p=0.038). Conclusion: Increasing the concentration of sulfur dioxide may cause decreased of lung function but other factor like personal protective equipment showed a significant correlation with lung function.
Current Developments of Smoking and Vaping, Is Vaping Safer? Arya Marganda Simanjuntak; Anastasya Hutapea; Bryan Steffanus Tampubolon; Stephani Browlim; Yosep Pebriyanto Napitupulu; Indi Esha Siregar; Suyanto Suyanto
Jurnal Respirasi Vol. 9 No. 2 (2023): May 2023
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v9-I.2.2023.159-168

Abstract

Vape fans claim that vaping is the solution to smoking cessation, but this is still debatable. Even if vape is still considered new, numerous studies show that vaping is associated with lung injury (EVALI). Despite this, the trend of vaping is still increasing. This study aimed to review the current understanding of conventional smoking and vaping and compare both. Is vaping safer than smoking? Smoking has health risks for lung cancer, chronic obstructive pulmonary disease (COPD), stroke, and others, while vaping has been linked with EVALI. Local perfusions were decreased in tobacco smokers after exposure. However, perfusion increased in vaping after exposure. Bronchoalveolar lavage (BAL) in vape users showed an increase of vitamin E acetate, possibly causing impairment in lung structure and functionality of surfactant. This is the potential mechanism of EVALI in vape users. Smoking uses the Brinkman Index to determine the severity of smoking, but there is no index for vaping because it depends not on how many sticks but on how many e-liquids were used. It seems that vape is "safer” than smoking, but smoking and vaping both have their own health risks, and it is safe to assume that neither is safe for use. "Vape is the solution for smoking cessation” needs further research because it takes years to understand conventional smoking in relation to other diseases. Prospective follow-up studies to determine the risk of vaping on other diseases are needed in the future.
Smoking Cessation: A Review Indi Esha; Riska Yuliana Sari
Respiratory Science Vol. 4 No. 1 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i1.100

Abstract

Smoking is a leading cause of preventable death worldwide. Smoking damages almost all organs and body systems and reduces the overall health of a person with the highest mortality, especially due to respiratory and cardiovascular disease. Evidence shows that the symptoms and prognosis of smoking-related diseases will improve after smoking cessation. Smoking cessation is one of the most important ways to improve the prognosis of patients with respiratory ailments. Counseling and treatment can increase the chances of smokers to successfully smoke cessation. Smoking cessation therapy must include pharmacological treatment (Nicotine Replacement Therapy (NRT), bupropion, varenicline or N-acetylcysteine) combined with nonpharmacological therapy.
Immunopathogenesis of Silicotuberculosis: A Literature Review Indi Esha; Elvando Tunggul Mauliate Simatupang
Respiratory Science Vol. 4 No. 1 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i1.103

Abstract

Silicotuberculosis is a tuberculosis infection that emerges as a silicosis complication. A silicosis patient is 2.8 to 39 times more likely to develop pulmonary tuberculosis (TB). Moreover, the fibrotic condition caused by silicosis may exacerbate the symptoms and worsen the clinical outcome of silicotuberculosis patients.  The current report suggests that the immune system plays an important role in the pathogenesis of this disease. Silicosis or silica exposure might interfere with the immunological response, especially the macrophages, which permit the Mycobacterium tuberculosis to infect the host. In this literature review, we will discuss the definition, epidemiology, and immunopathogenesis of silicotuberculosis.  
Profil Spirometri dan Gambaran Foto Thoraks pada Pekerja Pabrik Esha, Indi; Wijaya, Dewi; Adrianison, Adrianison; Simatupang, Elvando Tunggul Mauliate; Amaruddin, Amaruddin
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 16, No 3 (2025): Juli-September 2025
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf16300c

Abstract

Factory workers are a high-risk group for occupational lung disease. Exposure to dust particles, smoke, or gas during the work process can potentially cause lung damage. This is crucial in factory worker health management to prevent work-related lung disability. Therefore, a study was needed to determine the spirometry profile and chest radiographs in factory workers to anticipate the occurrence of occupational lung disease. This was a descriptive study involving 260 workers selected using a total sampling technique. Data collection in the form of radiological examinations was carried out for 3 months and analyzed descriptively. The results of the analysis showed that the proportion of impaired lung function in spirometry was 1.92% and lung abnormalities in chest radiographs was 2.69%. The highest distribution of factors, respectively, was found in workers aged >40 years (58.08%), male (97.31%), normoweight (63.07%), non-smokers (38.84%), no comorbidities (90.76%), and work duration ≤5 years (60.76%). Spirometry and chest X-ray are indicators that can be performed on factory workers as a risk factor for lung damage. Male workers, normoweight status, and the absence of comorbidities tend to contribute to the occurrence of lung abnormalities from simultaneous spirometry and chest X-ray examinations. Meanwhile, age, smoking status, and length of service have varying contributions to lung abnormalities in factory workers. In conclusion, this study shows that spirometry and chest X-ray examinations can be effective early detection tools for identifying the risk of occupational lung disease in factory workers, especially in high-risk groups.Keywords: factory workers; lung disorders; spirometry; chest X-ray ABSTRAK Pekerja pabrik adalah kelompok yang berisiko tinggi untuk mengalami penyakit paru akibat kerja. Pajanan partikel debu, asap ataupun gas selama proses bekerja akan berpotensi menyebabkan terjadinya kerusakan paru. Hal ini penting dalam manajemen kesehatan pekerja pabrik untuk mencegah terjadinya kecacatan paru akibat kerja. Untuk itu diperlukan penelitian yang bertujuan untuk mengetahui profil spirometri dan gambaran foto thoraks pada pekerja pabrik sehingga dapat mengantisipasi terjadinya penyakit paru akibat kerja. Penelitian ini merupakan studi deskriptif yang melibatkan 260 pekerja yang dipilih dengan teknik total sampling. Pengumpulan data berupa pemeriksaan radiologi dilakukan selama 3 bulan dan dianalisis secara deskriptif. Hasil analisis menunjukkan bahwa proporsi gangguan fungsi paru pada spirometri adalah 1,92% dan kelainan paru pada foto thoraks adalah 2,69%. Distribusi faktor tertinggi secara berurutan didapatkan pada pekerja yang berusia >40 tahun (58,08%), laki-laki (97,31%), normoweight (63,07%), tidak merokok (38,84%), tidak ada komorbid (90,76%) dan lama bekerja ≤5 tahun (60,76%). Pemeriksaan spirometri dan foto thoraks merupakan indikator yang dapat dilakukan pada pekerja pabrik sebagai salah satu faktor risiko yang dapat menyebabkan terjadinya kerusakan paru. Pekerja berjenis kelamin laki-laki, status normoweight dan tidak adanya komorbid cenderung berkontribusi terhadap terjadinya abnormalitas paru dari pemeriksaan spirometri dan foto thoraks secara bersamaan. Sementara usia, status merokok dan lama bekerja memiliki kontribusi yang bervariasi terhadap kelainan paru pada pekerja pabrik. Sebagai kesimpulan, penelitian ini menunjukkan bahwa pemeriksaan spirometri dan foto thoraks dapat menjadi alat deteksi dini yang efektif untuk mengidentifikasi risiko penyakit paru akibat kerja pada pekerja pabrik, terutama pada kelompok berisiko.Kata kunci: pekerja pabrik; gangguan paru; spirometri; foto thoraks