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Gambaran Jumlah Neutrofil Darah Tepi Pasien Penyakit Paru Obstruktif Kronik (PPOK) di Ruang Rawat Inap RSUD Arifin Achmad Provinsi Riau Tahun 2017 Qurnia Siti Hurul Aini; Adrianison Adrianison; Fridayenti Fridayenti
Jurnal Ilmu Kedokteran Vol 13, No 2 (2019): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v13i2.2019.63-69

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a common, preventable and treatable diesease that is characterized by progressive and persistent airflow limitation in respiratory tract and associated with an inflammatory response caused by exposure to noxious particles or gases. Several study showed that neutrophils are more activated and plays an important role in phatogenesis of COPD patients. The aim of this study is to know the description of peripheral blood neutrophil of COPD patients. This study was using descriptive retrospective design with total sampling technique. The sources of data were medical records of COPD patients in January – Desember 2017 with number of sample is 137 patients. The results of this study is COPD patients with high neutrophils were found in 94 (68,61%) patients. This study shows that COPD patients at lung wards Arifin Achmad Regional General Hospital Riau Province in 2017 obtained neutrophilia.
Risk Factors Affecting Respiratory Symptoms and Impaired Lung Function of Palm Oil Mill Workers in the District of Kandis Surya Hajar Fitria Dana; Indi Esha; Faisal Yunus; Adrianison Adrianison; Azizman Saad; Ridha Restilla
Jurnal Respirologi Indonesia Vol 41, No 3 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i3.194

Abstract

Background: Air pollution that exposed to human have been a problem all over the world and caused a variety of lung disease. Gases and particles emitted from industry including sulfur oxide, nitrogen oxide, and particulate matter may lead to decreasing lung function. Sulfur dioxide is one of the highest causes of air pollution at the highest level. Workers exposure to gases were vulnerable to respiratory function abnormality. Methods: A study on the effect of risk factors and sulfur dioxide exposure on lung function of palm oil workers in the district of Kandis was carried out in December 2019–January 2020. The research aim at describing sulfur dioxide air ambient in palm oil mill as well as respiratory state of palm oil workers and analyzing sulfur dioxide exposure and lung function relationship. Result: The result showed that sulfur dioxide concentration in outdoor 25.7 µg/Nm3 and indoor 20.6 µg/Nm3. The result of spirometry showed obstruction in 13% of the workers. Breathlessness and productive cough are the most common symptoms. Several factors that correlated with lung function namely as personal protective equipment (p=0.001), length of working (p=0.003), and smoking habit (p=0.004). From multivariate analysis, personal protective equipment has a significant correlation with lung function (p=0.038). Conclusion: Increasing the concentration of sulfur dioxide may cause decreased of lung function but other factor like personal protective equipment showed a significant correlation with lung function.
Chronic Obstructive Pulmonary Disease with Incidence of Heart Failure and Its Influencing Factors Andry Wahyudi Agus; Adrianison Adrianison; Dyah Siswanti Estiningsih; Faisal Yunus; Zahtamal Zahtamal
Jurnal Respirasi Vol. 8 No. 1 (2022): January 2022
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (334.306 KB) | DOI: 10.20473/jr.v8-I.1.2022.7-14

Abstract

Introduction: Chronic obstructive pulmonary disease (COPD) is often associated with cardiovascular disease because it has the same risk factors as smoking. One of the cardiovascular complications in COPD is heart failure. Echocardiography examination is a tool to evaluate changes of the heart both anatomically and functionally. This study aimed to determine the relationship between COPD and heart failure by echocardiography examination in stable COPD patients.Methods: This was a descriptive-analytic study using a cross-sectional design for COPD patients who visited the Lung Polyclinic of Arifin Achmad Hospital, Pekanbaru, Riau, which was conducted from November 2020 to March 2021. Subjects who met the inclusion criteria were examined by spirometry, chest X-rays, and echocardiography.Results: In this study, there were 66 stable COPD subjects. It was found that 15.2% of subjects had right heart failure based on the tricuspid annular plain systolic excursion (TAPSE) assessment and 7.6% of the subjects had left heart failure based on the left ventricular ejection fraction (LVEF) value. Right ventricular dilatation (p = 0.000), right ventricular dysfunction (p = 0.005), and increased probability of pulmonary hypertension (PH) (p = 0.000) were significantly associated with a decrease in the first second forced expiratory volume (FEV1).Conclusion: The severity of COPD with FEV1 <50% had a significant relationship with dilatation, dysfunction of right ventricular, and increased the probability of incidence of PH based on parameters tricuspid regurgitation (TR). A history of exacerbations ≥2 times in a year caused right ventricular dilatation, decreased right ventricular function, and increased the probability of PH.
Tinjauan Pustaka: Sindrom Vena Kava Superior Chyntia Triana Putri; Adrianison Adrianison; Sri Melati Munir
Jurnal Ilmu Kedokteran Vol 18, No 1 (2024): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v18i1.2024.1-10

Abstract

Superior Vena Cava Syndrome (SVCS) includes various clinical signs and symptoms due to external compression and intrinsic obstruction of superior vena cava (SVC) itself or the superior cavo-atrial junction that cause reducing of blood flow. Infection becomes main etiology in previous decades but development in antibiotics treatment and improvement of socio-economyc condition made incidence of SVCS due to infection decreased. SVCS due to malignancy recently reach 60-90% of overall cases. 78-85% of SVC obstructions due to malignancy are caused by lung cancer and 80% of it is right lesion. Historically SVCS is considered as an oncology emergency condition and become one of a few indications for palliative radiotherapy. This literature review will explain the pathophysiology, etiology, diagnosis and management of SVCS with the aim of providing timely and effective intervention to treat the causes of this syndrome so that it can significantly relieve symptoms and improve the quality of life of patients with SVCS.