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All Journal Majalah Kedokteran Oto Rhino Laryngologica Indonesiana Indonesian Journal of Global Health research Indonesian Journal of Global Health Research
Lina Marlina
Departemen Ilmu KesehatanTelinga Hidung Tenggorok-Bedah Kepala Leher Fakultas Kedokteran Universitas Kristen Indonesia/Rumah Sakit Universitas Kristen Indonesia
Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

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Profile of Allergic Rhinitis Based on Nasal Eosinophil Count, Total Nasal Symptoms Score and Peak Nasal Inspiratory Flow Bambang S. R.Utomo; Lina Marlina; Fransiskus Poluan; Jurita Falorin; Danny Luhulima; Yunita R.M. B. Sitompul
Majalah Kedokteran UKI Vol. 35 No. 1 (2019): JANUARI - MARET
Publisher : Fakultas Kedokteran Universitas Kristen Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/mkvol34iss2pp60

Abstract

Abstract Allergic rhinitis (AR) is a symptomatic disorder of the nose induced after allergen exposure by an immunoglobulin E (IgE)-mediated inflammation of the membranes lining the nose. The manifestation of AR can affect patients’ quality of life. The objective of this study was to evaluate the profile of allergic rhinitis patients in term of nasal eosinophil count, total nasal symptom score (TNSS) and peak nasal inspiratory flow (PNIF). Fourteen allergic rhinitis patients were evaluated using the nasal eosinophil count with Wright-Giemsa staining, total nasal symptom score, and PNIF. The study comprised of 6 (42.9%) men, and 8 (57.1%) women with a mean of age 21.15±3.78 years. Participants’ symptoms and characteristics included sneezing (42%), nasal blockage (21.4%), itchy nose (21.4%), and rinorrhea (14.3%) with a mean TNSS of 8.2±1.8. Intermittent AR was found in 14.3% subjects, persistent AR 78.6%, mild AR 21.4%, and moderate-severe AR 78.6%. The mean PNIF was 80±27.46 L/min, and mean eosinophil count of 2.5±1.74. In conclusion, allergic rhinitis patients demonstrated positive nasal eosinophil count with Wright-Giemsa staining, with the majority of them having persistent and moderate-severe RA. They also had nasal airflow impairment, which could affect quality of life.Keywords: allergic rhinitis, eosinophil, nasal airflow, quality of life. Abstrak Rhinitas alergika (RA) merupakan kelainan pada hidung yang diinduksi oleh pajanan alergen yang berhubungan dengan reaksi inflamasi yang diperantarai IgE pada mokusa hidung. Manifestasi RA dapat mempengaruhi kualitas hidup pasien. Tujuan penelitian ini adalah simptomatik evaluasi profil pasien RA dari segi hitung eosinofil nasal, skor total sindrom nasal (TNSS) dan aliran inspirasi nasal (PNIF). Empat belas pasien RA dievaluasi jumlah eosinofil nasal dengan pewarnaan Wright-Giemsa, skor total simtom nasal dan PNIF. Terdapat 6 (42,9%) laki –laki dan 8 (57,1%) perempuan dengan umur rata-rata usia 21,15±3.78 tahun. Simtom dan karakteristik pasien yaitu bersin (42%), sumbatan hidung (21,4%), hidung gatal (21,4%) dan rinorea (14,3%), dengan rata-rata TNSS 8.2±1.8. Rinitas alergika intermiten ditemukan pada 14,3% subyek, yang persisten 78,6%, sedang 21,4% serta sedang-berat 78,6%. Rata-rata PNIF 80±27.46 L/menit, serta rata-rata jumlah eosinofil 2.5±1.74. Dapat disimpulkan pasien RA menunjukkan jumlah eosinofil nasal positif dengan pewarnaan Wright- Giemsa dan kebanyakan memiliki RA yang persisten dengan tingkat sedang-berat. Terdapat juga gangguan aliran udara hidung yang mungkin mempengaruhi kualitas hidup mereka. Kata Kunci: rinitis alergika, eosinofil, aliran udara hidung, kualitas hidung
Hubungan antara Gangguan Pendengaran dan Kualitas Hidup pada Orang Lanjut Usia Destinea Silvanaputri; Bambang S. R. Utomo; Lina Marlina; Fransiskus Poluan; Jurita Falorin; Julita M. Dewi; Dame J. Pohan
Majalah Kedokteran UKI Vol. 35 No. 2 (2019): APRIL - JUNI
Publisher : Fakultas Kedokteran Universitas Kristen Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/mkvol34iss2pp60

Abstract

Abstrak Menurut data USA-Bureau of the census, Indonesia diperkirakan akan mengalami pertambahan warga lansia terbesar di seluruh dunia antara tahun 1990-2025, yaitu sebanyak 414%. Sejalan dengan bertambahnya usia harapan hidup di Indonesia, masalah kesehatan bagi usia lanjut akan semakin banyak, salah satunya adalah gangguan pendengaran. Pada individu yang berusia lebih dari 65 tahun, sekitar 30% di antaranya mengalami penurunan fungsi pendengaran (presbiskusis) dan setelah usia 75 tahun, angka tersebut meningkat menjadi 50%. Masalah pendengaran dapat berpengaruh pada kualitas hidup lansia. Penelitian ini bertujuan untuk mengetahui hubungan antara gangguan pendengaran dan kualitas hidup pada lansia di Sasana Tresna Werdha Karyabakti Ria Pembangunan Cibubur. Penelitian ini menggunakan metode penelitian cross sectional. Teknik sampling pada penelitian ini adalah total sampling dengan jumlah sampel sebanyak 48 orang. Responden mengisi dua kuesioner, yaitu Hearing handicap inventory elderly-screening version (HHIE-S) dan World Health Organization quality of life (WHOQOL-BREF). Terdapat kecenderungan bahwa lansia yang memiliki gangguan pendengaran berisiko lebih besar untuk memiliki kualitas hidup yang kurang baik, walaupun hubungan tidak bermakna (odds ratio 2,0; 95% confidence interval 0,49,7; p=0,605). Diperlukan sampel penelitian yang lebih besar dan desain penelitian yang lebih baik untuk meneliti lebih lanjut hubungan antara gangguan pendengaran dan kualitas hidup pada lansia.Kata kunci: Lanjut usia, gangguan pendengaran, HHIE-S, kualitas hidup, WHOQOL-BREF Abstract According the data from USA Bureau of the census, Indonesia is expected to experience the largest increase (414%) in elderly citizens worldwide between 1990-2025. In line with the increasing life expectancy of the people in Indonesia, there will be more health problems for the elderly, for example hearing loss. In individuals aged over 65 years old, about 30% of them experience decreasing hearing ability (presbiskusis) and after 75 years old, that number increases to 50%. Hearing problem can affect to the quality of life of the elderly. This research aimed to determine the relationship of hearing loss with the quality of life for elderly in Sasana Tresna Werdha Karyabakti Ria Pembangunan Cibubur. This research used a cross sectional method with total sampling technique. All 48 respondents filled out two questionnaries: the hearing handicap inventory elderly-screening version (HHIE-S) and the World Health Organization Quality of Life (WHOQOL-BREF). From the results of the analysis, it was found that respondents with poor hearing quality had a higher risk of having poor quality of life, although the association was not significant (odds ratio 2,0; 95% confidence interval 0,4-9,7; p=0,605). Bigger study with better design is needed to evaluate the relationship between hearing loss and qulaity of life in elederly.Keywords: Elderly, hearing loss, HHIE-S, quality of life, WHOQOL-BREF.
Pola Kepekaan Bakteri yang Diisolasi dari Liang Telinga Penderita Otitis Media Supuratif Kronis Terhadap Antibiotik Noni N. Sari; Bambang S. R. Utomo; Lina Marlina; Fransiscus H. Poluan; Dame J. Pohan
Majalah Kedokteran UKI Vol. 35 No. 4 (2019): OKTOBER-DESEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/mkvol34iss2pp60

Abstract

AbstrakOtitis media supuratif kronis (OMSK) merupakan infeksi telinga tengah yang ditandai dengan keluarnya sekret dari telinga lebih dari dua bulan, sekret cair atau kental berwarna bening atau seperti nanah, frekuensi terus-menerus atau hilang timbul, dan membran timpani mengalami perforasi. Pengobatan konservatif pada OMSK adalah antibiotik topikal dan sistemik. Pola sensitivitas mikroba berubah dari waktu ke waktu, sehingga tujuan penelitian ini adalah untuk mengetahui sensitivitas antibiotik pada bakteri sekret telinga penderita OMSK. Penelitian menggunakan metode deskriptif dengan desain case series. Pengambilan data dilakukan dengan total sampling, yaitu seluruh pasien OMSK yang datang ke Rumah Sakit Universitas Kristen Indonesia, memenuhi kriteria inklusi dan eksklusi, pada bulan Agustus 2019 hingga November 2019. Dari 16 responden penderita OMSK, terdapat 10 laki-laki (62,4%), 5 berasal dari kelompok usia 0-10 tahun (31,2%), dan 16 memiliki keluhan utama keluar cairan (93,8%). Kuman terbanyak adalah Staphylococcus aureus (6 atau 35,3%), sensitivitas antibiotik tertinggi adalah Imipenem (16 atau 94.4%), diikuti gentamisin (13 atau 76,5%) dan Amikasin (13 atau 76.5%). Antibiotik resistensi tertinggi adalah kloramfenikol (13 atau 76,5%), diikuti eritromisin (13 atau 76.5%) dan amoksisilin (7 atau 70,6%).Kata kunci: Otitis media supuratif kronis (OMSK), sekret telinga, kultur, sensitifitas antibiotik. AbstractChronic suppurative otitis media (CSOM) is an infection of the middle ear characterized by secretions from the ear for more than two months, liquid or thick discharge that is clear or pus-like, continuous frequency or recurrent, with a tympanic membrane perforation. Topical and systemic antibiotics are used to treat CSOM. The pattern of microbial sensitivity can changes over time, and the purpose of this study was to evaluate the sensitivity of antibiotics in CSOM patients. This study used a descriptive method with a case series design. Total sampling was done by including all CSOM patients who came to the Indonesian Christian University Hospital from August 2019 to November 2019 based on the inclusion and exclusion criteria. Of 16 respondents with CSOM, there 10 males (62.4%), 5 were in the age group of 0-10 years (31.2%), and 16 had the main complaint of fluid discharge (93.8%). The most common bacteria were Staphylococcus aureus (6 or 35.3%), antibiotic with the highest sensitivity were imipenem (16 or 94.4%), gentamicin (13 or 76.5%) and amikacin (13 or 76.5%). Antibiotics with the highest resistance were chloramphenicol (13 or 76.5%), erythromicin (13 or 76.5%) and amoxicillin (7 or 70.6%).Keywords: Chronic suppurative otitis media (CSOM), culture, ear secretions, antibiotic susceptibility.
Bakteri Penyebab Otitis Media Supuratif Kronis di Rumah Sakit Umum Universitas Kristen Indonesia Tio Dora Parhusip; Bambang Suprayogi Resi Utomo; Lina Marlina; Fransiscus Harp Poluan; Jurita Falorin; Adli Nurfachri; Dame Joice Pohan
Majalah Kedokteran UKI Vol. 36 No. 1 (2020): JANUARI-APRIL
Publisher : Fakultas Kedokteran Universitas Kristen Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/mk.v36i1.2988

Abstract

Abstrak Otitis media supuratif kronis (OMSK) merupakan inflamasi dari telinga tengah dan rongga mastoid kronis, ditandai dengan perforasi membran timpani serta cairan yang keluar dari telinga secara persisten. Gangguan pendengaran dan kecacatan umumnya disebabkan oleh OMSK. Komplikasi otitis media supuratif kronis lainnya dapat menyebabkan infeksi intrakranial yang fatal dan mastoiditis akut, terutama di Negara-negara berkembang. Penatalaksanaan yang efektif tergantung pada pengetahuan mengenai mikroorganisme penyebab dan sensitivitas mikroba. Penelitian ini bertujuan untuk mengetahui pola bakteri penyebab otitis media supuratif kronis di Rumah Sakit Umum Universitas Kristen Indonesia Tahun 2019. Metode penelitian yang digunakan adalah deskriptif dengan pendekatan secara clinical series yang dilakukan dari bulan Agustus 2019 sampai November 2019 di Poliklinik THT-KL RSU UKI dan Laboratorium Mikrobiologi FK UKI. Hasil dari 17 sampel menunjukkan bahwa Staphylococcus aureus merupakan bakteri terbanyak yang ditemukan pada penderita OMSK yaitu 6 (35,3%), diikuti Pseudomonas aerugenosa 5 (29,4%), Staphylococcus epidermidis 2 (11,8%), Klebsiella spp. 2 (11,8%), Proteus spp. 1 (5,9%), Escherichia coli 1 (5,9%). Kata kunci :otitis media supuratif kronis, pola bakteri. Abstract Chronic suppurative otitis media (CSOM) is a chronic inflammation of the middle ear and mastoid cavity, followed with recurrent ear discharges or otorrhoea through a tympanic perforation. Hearing impairment and disability are generally caused by CSOM. Other complications of chronic suppurative otitis media can lead to fatal intracranial infections and acute mastoiditis, especially in developing countries. Effectivity of the disease management depends on the knowledge of causative microorganisms and their antimicrobial sensitivity. The purpose of this study is to identify the bacterial pattern that cause chronic suppurative otitis media in Christian University of Indonesia General Hospital in 2019. This study is using the descriptive method with a clinical series approach, this study was carried out from August 2019 to November 2019 at the polyclinic of ENT-HNS RSU UKI and Microbiology Laboratory FK UKI. The results of 17 samples showed Staphylococcus aureus was the most bacteria found in CSOM patient 6 samples (35,3%), followed Pseudomonas aerugenosa 5 (29,4%), Staphylococcus epidermidis 2 (11,8%), Klebsiella spp. 2 (11,8%), Proteus spp. 1 (5,9%), Escherichia coli 1 (5,9%). Keywords: chronic suppurative otitis media, bacterial pattern
Tatalaksana Trauma Wajah dengan Panfasial Fraktur Lina Marlina; Bambang S.R. Utomo; Fransiskus H. Poluan
Majalah Kedokteran UKI Vol. 36 No. 3 (2020): SEPTEMBER - DESEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/mk.v36i3.3362

Abstract

AbstrakFraktur pada wajah dapat menyebabkan defisit fungsional dan estetika jika tidak ditangani dengan baik. Tatalaksana akut yang tepat dari fraktur wajah harus didasarkan pada evaluasi cepat dan menyeluruh. Keberhasilan rekontruksi wajah merupakan keadaan darurat yang perlu dievaluasi dalam waktu 24 jam dari trauma. Berbagai jenis reduksi dan fiksasi tergantung pada fungsi, lokasi, jenis fraktur, dan usia pasien. Kasus ini diajukan untuk memperlihatkan keberhasilan tatalaksana trauma akut maksilofasial. Dilaporkan seorang laki-laki 37 tahun dengan panfasial fraktur yang dilakukan reduksi dan fiksasi 3 hari setelah trauma dengan pemasangan plat dan sekrup, serta fiksasi mukoginggival kombinasi antara arch bardan quickfix. Reduksi, reposisi dan fiksasi dilakukan setelah edema mukosa hebat disertai kombinasi antara arch bar dan quickfix pada mukoginggival merupakan salah satu alternatif untuk mengurangi risiko perdarahan dan memudahkan reposisi.Kata kunci: fraktur wajah, panfasial fraktur,edema mukosa.Management of Maxillofacial Traumawith Panfacial FractureAbstractFacial fractures can cause functional and aesthetic deficits if not treated properly. Appropriate acute management of facial fractures should be based on a rapid and thorough evaluation. Successful facial reconstruction is an emergency that needs to be evaluated within 24 hours of trauma. Different types of reduction and fixation depend on the function, location, type of fracture, and the age of the patient. This case is presented to demonstrate the success of acute maxillofacial trauma management. Reported a 37-year-old man with a facial fracture who underwent reduction and fixation 3 days after trauma with plate and screw installation, and combination mucogingival fixation between arch bar and quickfix. Reduction, reposition and fixation performed after severe mucosal edema accompanied by a combination of arch bar and quickfix on the mucogingival is an alternative to reduce the risk of bleeding and facilitate repositioning.Keywords: facial fracture, panfacial fracture, mucosal edema.
Impact of Pharmacotherapy to decrease Interleukin-6 in patients with chronic rhinosinusitis without nasal polyp Lina Marlina; Sinta Sari Ratunanda; Teti Madiadipoera
Oto Rhino Laryngologica Indonesiana Vol 50, No 1 (2020): Volume 50, No. 1 January - June 2020
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (302.035 KB) | DOI: 10.32637/orli.v50i1.350

Abstract

Background: Chronic rhinosinusitis (CRS) is an inflammation of the nasal and paranasal sinuses mucosa, ongoing for more than 12 weeks. Even now it still creates socioeconomic problem in both developed and developing countries. Pharmacotherapy administration is essential for decreasing the severity of symptom, improving quality of life, and decreasing interleukin (IL)-6 level. Objective: To find out the effect of pharmacotherapy on severity of the symptom, quality of life, and IL-6 level. Method: Randomized clinical trial with pre and posttest design, on 20 CRS without polyp patients, divided into two groups based on skin prick test results. Both groups were equally treated with nasal irrigation, nasal corticosteroid, and antibiotic amoxicillin clavulanate for 14 days. All subjects were assessed for Visual Analog Scale (VAS) score, nasoendoscopy (NE) score, Sinonasal Outcome test (SNOT)-22, and IL-6 level. Statistical analysis was performed with Mann Whitney and Wilcoxon methods. Result: There were significant differences in total analysis results on VAS scores, NE scores, SNOT-22, and IL-6 levels in both groups, with values p<0.05. There was improvement in all variables after pharmacotherapy, but there was no significant difference between the case and control groups, with values p>0.05. Conclusion: Pharmacotherapy in both groups resulte’ in reduced severity of symptoms, improved quality of lives, and decreased IL-6 levels.Keywords: Interleukin-6, pharmacotherapy, chronic rhinosinusitis without polyp, quality of life ABSTRAK Latar belakang: Rinosinusitis kronik (RSK) merupakan inflamasi pada mukosa hidung dan sinus paranasal, yang berlangsung selama lebih dari 12 minggu. Hingga saat ini masih memengaruhi sosioekonomi di negara maju maupun negara berkembang. Pemberian farmakoterapi sangat penting untuk memperbaiki derajat gejala, meningkatkan kualitas hidup, dan menurunkan kadar interleukin (IL)-6. Tujuan: Mengetahui pengaruh pemberian farmakoterapi terhadap perbaikan derajat gejala, peningkatan kualitas hidup, dan penurunan kadar IL-6. Metode: Penelitian kuasi eksperimental, label terbuka pra dan pascaterapi, pada 20 penderita RSK tanpa polip, dibagi dua kelompok berdasarkan hasil uji tusuk kulit. Perlakuan pada kedua kelompok sama, diberikan irigasi hidung, kortikosteroid intranasal, dan antibiotik amoksisilin klavulanat selama 14 hari. Penelitian dilakukan dengan menilai skor Visual Analog Scale (VAS) gejala hidung, skor nasoendoskopi (NE), Sinonasal Outcome test (SNOT)-22, dan kadar IL-6. Analisis statistik menggunakan metode Mann Whitney dan Wilcoxon. Hasil: Didapati perbedaan bermakna pada hasil analisis total pada skor VAS gejala hidung, skor NE, SNOT-22, dan kadar IL-6 pada kedua kelompok dengan nilai p<0,05. Didapati perbaikan pada semua variabel setelah 14 hari pemberian medikamentosa maksimal, namun tidak terdapat perbedaan bermakna antara kedua kelompok dengan nilai p>0,05. Kesimpulan: Pemberian farmakoterapi pada kedua kelompok memberikan hasil berupa perbaikan derajat gejala, peningkatan kualitas hidup, dan penurunan kadar IL-6.
Impact of Pharmacotherapy to decrease Interleukin-6 in patients with chronic rhinosinusitis without nasal polyp Lina Marlina; Sinta Sari Ratunanda; Teti Madiadipoera
Oto Rhino Laryngologica Indonesiana Vol. 50 No. 1 (2020): Volume 50, No. 1 January - June 2020
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v50i1.350

Abstract

Background: Chronic rhinosinusitis (CRS) is an inflammation of the nasal and paranasal sinuses mucosa, ongoing for more than 12 weeks. Even now it still creates socioeconomic problem in both developed and developing countries. Pharmacotherapy administration is essential for decreasing the severity of symptom, improving quality of life, and decreasing interleukin (IL)-6 level. Objective: To find out the effect of pharmacotherapy on severity of the symptom, quality of life, and IL-6 level. Method: Randomized clinical trial with pre and posttest design, on 20 CRS without polyp patients, divided into two groups based on skin prick test results. Both groups were equally treated with nasal irrigation, nasal corticosteroid, and antibiotic amoxicillin clavulanate for 14 days. All subjects were assessed for Visual Analog Scale (VAS) score, nasoendoscopy (NE) score, Sinonasal Outcome test (SNOT)-22, and IL-6 level. Statistical analysis was performed with Mann Whitney and Wilcoxon methods. Result: There were significant differences in total analysis results on VAS scores, NE scores, SNOT-22, and IL-6 levels in both groups, with values p<0.05. There was improvement in all variables after pharmacotherapy, but there was no significant difference between the case and control groups, with values p>0.05. Conclusion: Pharmacotherapy in both groups resulte’ in reduced severity of symptoms, improved quality of lives, and decreased IL-6 levels.Keywords: Interleukin-6, pharmacotherapy, chronic rhinosinusitis without polyp, quality of life ABSTRAK Latar belakang: Rinosinusitis kronik (RSK) merupakan inflamasi pada mukosa hidung dan sinus paranasal, yang berlangsung selama lebih dari 12 minggu. Hingga saat ini masih memengaruhi sosioekonomi di negara maju maupun negara berkembang. Pemberian farmakoterapi sangat penting untuk memperbaiki derajat gejala, meningkatkan kualitas hidup, dan menurunkan kadar interleukin (IL)-6. Tujuan: Mengetahui pengaruh pemberian farmakoterapi terhadap perbaikan derajat gejala, peningkatan kualitas hidup, dan penurunan kadar IL-6. Metode: Penelitian kuasi eksperimental, label terbuka pra dan pascaterapi, pada 20 penderita RSK tanpa polip, dibagi dua kelompok berdasarkan hasil uji tusuk kulit. Perlakuan pada kedua kelompok sama, diberikan irigasi hidung, kortikosteroid intranasal, dan antibiotik amoksisilin klavulanat selama 14 hari. Penelitian dilakukan dengan menilai skor Visual Analog Scale (VAS) gejala hidung, skor nasoendoskopi (NE), Sinonasal Outcome test (SNOT)-22, dan kadar IL-6. Analisis statistik menggunakan metode Mann Whitney dan Wilcoxon. Hasil: Didapati perbedaan bermakna pada hasil analisis total pada skor VAS gejala hidung, skor NE, SNOT-22, dan kadar IL-6 pada kedua kelompok dengan nilai p<0,05. Didapati perbaikan pada semua variabel setelah 14 hari pemberian medikamentosa maksimal, namun tidak terdapat perbedaan bermakna antara kedua kelompok dengan nilai p>0,05. Kesimpulan: Pemberian farmakoterapi pada kedua kelompok memberikan hasil berupa perbaikan derajat gejala, peningkatan kualitas hidup, dan penurunan kadar IL-6.
Chronic Rhinosinusitis with Dextra ET Sinistra Nasal Polyps Lina Marlina; Nildi Selan; Tranggono Yudo Utomo
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6648

Abstract

Chronic rhinosinusitis with nasal polyps is a chronic inflammatory condition of the nasal mucosa and paranasal sinuses, characterized by bilateral polypoid tissue growth. This disease can significantly reduce quality of life due to persistent and recurrent symptoms. This report aims to describe a case of chronic rhinosinusitis with right and left nasal polyps, including risk factors, clinical features, supporting examination results, and patient management and follow-up. This study is a descriptive case report involving one patient with bilateral chronic nasal congestion, anosmia, and rhinorrhea that lasted more than 12 weeks. Data were collected through anamnesis, physical examination, nasoendoscopy, CT scan imaging, and patient medical records. Data analysis was performed qualitatively by describing the clinical course, supporting examination results, therapeutic interventions, and patient follow-up evaluation. The patient experienced significant improvement post-operatively with decreased symptoms, increased quality of life, and no polyp recurrence was found within 3 months after the procedure. Appropriate diagnosis and management of chronic rhinosinusitis with bilateral nasal polyps are essential to prevent complications and improve patient prognosis.
Persistent Hoarseness Associated with Laryngopharyngeal Reflux and Suspected Ortner’s Syndrome: A Case Report Yusticia Maharani; Lina Marlina
Indonesian Journal of Global Health Research Vol. 8 No. 4 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i4.2185

Abstract

Laryngopharyngeal reflux (LPR) is an extraesophageal inflammatory disorder caused by the retrograde flow of gastric contents into the laryngopharyngeal region, leading to chronic irritation of the upper airway mucosa. Persistent hoarseness is a common symptom; however, dysphonia may also reflect rare cardiovascular causes such as Ortner’s syndrome (cardiovocal syndrome), which results from recurrent laryngeal nerve dysfunction secondary to cardiovascular pathology. Diagnostic differentiation between these entities can be challenging due to overlapping clinical features. We report a 70-year-old woman with two months of persistent hoarseness following coronary artery stenting after myocardial infarction. She also experienced nocturnal cough, globus sensation, intermittent choking, and dysphagia. Flexible laryngoscopy showed bilateral vocal fold hyperemia and edema, posterior commissure hypertrophy, and partial glottic narrowing. The Reflux Symptom Index (RSI) score was 22 and the Reflux Finding Score (RFS) was 17, supporting LPR. Coronary angiography revealed total occlusion of the right coronary artery. Given her significant cardiovascular history, recurrent laryngeal nerve involvement due to suspected Ortner’s syndrome was also considered. This case highlights overlapping manifestations of LPR and cardiovocal syndrome, complicating diagnosis. Comprehensive multidisciplinary evaluation is essential, particularly in elderly patients with cardiovascular disease, to avoid attributing persistent hoarseness solely to reflux and to identify potential cardiogenic causes of dysphonia.
Co-Authors Adli Nurfachri Bambang Suprayogi Resi Utomo Dame J. Pohan Dame J. Pohan Dame Joice Pohan Danny Luhulima Destinea Silvanaputri Fransiscus H. Poluan Fransiscus Harp Poluan Fransiskus H. Poluan Fransiskus Poluan Fransiskus Poluan Julita M. Dewi Jurita Falorin Jurita Falorin Jurita Falorin Nildi Selan Noni N. Sari Sinta Sari Ratunanda Teti Madiadipoera Tio Dora Parhusip Tranggono Yudo Utomo Yunita R.M. B. Sitompul Yusticia Maharani