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All Journal Journal of Islamic Pharmacy Jurnal Ilmu Kefarmasian Indonesia
Andini Andini
Akademi Farmasi Putra Indonesia Malang
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Pengaruh Konsentrasi Fraksi Etil Asetat Bangle Terhadap Nilai SPF Krim Ekstrak Temugiring Anisa Lailatusy Syarifah; Andini Andini; Haritsah Alfad
JURNAL ILMU KEFARMASIAN INDONESIA Vol 20 No 1 (2022): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v20i1.1214

Abstract

The concentration of bangle (Zingiber cassumunar) ethyl acetate fraction added in the formulation of the temugiring (Curcuma heyneana) extract cream formulation must be determined precisely since it may affect the Sun Protection Factor (SPF) value. This research aims to determine the effect of concentration variations of bangle ethyl acetate fraction on the SPF value of the temugiring extract cream. In this research, temugiring extract and bangle extract were obtained by remaceration employing ethanol, while the bangle ethyl acetate fraction was obtained by fractionation using n-hexane, ethyl acetate, methanol, and water. The bangle ethyl acetate fraction obtained was formulated in cream formulations of temugiring extract formulas 1, 2, and 3 with variations in the concentration of bangle ethyl acetate fraction 2%; 3%; and 4%. Furthermore, the SPF value was conducted using the UV-Vis spectrophotometry method. The results show that bangle ethyl acetate fraction concentration variations produced different SPF values for each cream formula. The SPF value for formulas 1, 2, and 3 was 11.466; 12.122; and 17.266. One Way ANOVA test produced a p-value of 0.037. Thus, it can be concluded that the concentration of the bangle ethyl acetate fraction would affect the SPF value in the cream temugiring extract.
Pengaruh Variasi Konsentrasi Ekstrak Temugiring (Curcuma heyneana) dalam Sediaan Krim Terhadap Nilai SPF Anisa Lailatusy Syarifah; Andini Andini; Haritsah Alfad; Auril Alfurida
Journal of Islamic Pharmacy Vol 6, No 2 (2021): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v6i2.14336

Abstract

Temugiring (Curcuma heyneana) mengandung senyawa flavonoid dan kurkumin yang berpotensi sebagai tabir surya, sehingga konsentrasi ekstrak yang ditambahkan dalam formulasi sediaan krim harus ditentukan secara tepat karena akan berpengaruh terhadap mutu fisik dan nilai Sun Protection Factor (SPF). Tujuan penelitian ini adalah mengetahui pengaruh variasi konsentrasi ekstrak temugiring terhadap mutu fisik dan nilai SPF krim. Dalam penelitian ini, ekstrak temugiring diperoleh dari metode maserasi menggunakan pelarut etanol 96%, kemudian diformulasikan dalam sediaan krim dengan variasi konsentrasi ekstrak 5%; 7,5%; dan 10%. Selanjutnya, penentuan nilai SPF dilakukan dengan metode spektrofotometri UV-Vis. Hasil penelitian menunjukkan variasi konsentrasi ekstrak temugiring menyebabkan nilai SPF yang berbeda pada setiap formula. Nilai SPF formula 1, 2, dan 3 adalah 3,307±0,11; 3,497±0,18; 4,966±0,24. Uji One Way Anova menghasilkan p-value 0,05.  Dengan demikian, dapat disimpulkan bahwa konsentrasi fraksi etil asetat bangle berpengaruh terhadap nilai SPFnya.Kata Kunci: Curcuma heyneana, krim, sun protection factor, temugiring
Co-Authors Auril Alfurida Haritsah Alfad Syarifah, Anisa Lailatusy