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All Journal Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Plastik Rekonstruksi
Sukasah, Chaula Luthfia
Faculty Of Medicine University Of Indonesia/ Dr. Cipto Mangunkusumo, Jakarta
Civil Engineering, Building, Construction & Architecture Immunology & microbiology Neuroscience Other

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Micro-vascular surgery in fingertip injury treatment: Case report Rosadi Seswandhana Teddy OH Prasetyono Chaula Sukasah
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 43, No 02 (2011)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (189.725 KB)

Abstract

A high priority for fingertip injury reconstruction is the restoration of skin cover to protect underlying bone, tendon,and nerve structures. Other priorities are to maintain or maximize sensibility, preserve digit length, and minimizecosmetic deformity. Because it is so highly visible, though, the appearance of the reconstructed digit should be asnormal as possible. Therefore, microvascular surgery has an important role in management of fingertip injuries togive a normal shape of the digit. In this case, a clinical experience using microvascular surgery in the treatment offingertip injury was reported. In early 2007, there were two fingertip injury cases which were reconstructed usingmicrovascular surgery modality. The first case was a 34 years old male who had defect in soft tissue of the fourthfinger in his right hand caused by pressed machine. We performed elective wound reconstruction by transferring theskin and soft tissue freely (free pulp transfer) along with the vasculatures taken from fibular side of great toe in theright foot. Revascularization was performed by connecting deep plantar artery/vein with common digital artery/veinat the injured digit. The second case, was a 29 years old female with clean-cut amputation of the distal part of thethird finger in the right hand (Allen’s type IV). We performed replantation in the first 16 hours after injury. Wereanastomosed the ulnar side of digital artery only without vein and nerve reanastomosis. To avoid the distal edema,we did not perform any skin suture and let the oozing from the vein backflow. In both cases, we have excellentappearance result, moderate usefulness of the finger, but still poor in sensibility.Key words: clinical experiences - fingertip injury - soft tissue defect - clean cut amputation - microvascular surgery- free pulp transfer - replantation.
Clto open heart as operative treatment of foreign body In the left ventricle removal M. Rosadi Seswandhana M. Rosadi Seswandhana
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 35, No 2 (2003)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Foreign body in the left ventricle is rare and it is associated most commonly with significant trauma. The diagnosis of a foreign body in the left ventricle can be difficult. One must distinguish between foreign matter in the cardiac chamber or free-floating in the mediastinum. Our case was male, 38 years old. He presented not only with typical complaints of chest pain and dyspnea, but also with the complaint of a "foreign body" in the right of his chest after a work accident. Physical examination and serial chest X-rays on the earlier survey showed right hemothorax and foreign body appearance on the back wall of the heart. Insertion of chest tube with water sealed drainage was done as a primary treatment. On the echocardiography and fluoroscopy examination, we found foreign body appearance in the left ventricle. To prevent myocarditis, either sterile or non-sterile, with potential for other significant complications, removal of an intraventricle foreign body is always indicated. Cito open heart with heart-lung machine was performed to extract the foreign body. There was no complication after 7 month evaluation.Key words: Foreign body removal - In the left ventricle - Work accident - Cito open heart
Chronic wound mitomycin-c-induced animal models Andreas Ariawan; Aditya Wicaksana; Aditya Rifqi Fauzi; Rosadi Seswandhana*
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 50, No 2 (2018)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (818.646 KB) | DOI: 10.19106/JMedSci005002201803

Abstract

ABSTRACTChronic wound is a problem often encountered, especially in areas that do not have adequate health facilities. Some of the factors that caused the injury are mechanical, chemical, electrical, or heat. Chronic inflammation and bacterial infections are the two major factors that affect the process of wound chronicity. Mitomycin-C (MMC) is widely used as an intravenous, oral, and topical anti-cancer drug. MMC that is applied topically to a wound can cause cross-linking and decrease or stop the process of DNA transcription so that the wound will not develop the healing phase because MMC works as an inhibitor of fibroblast and proliferation that can inhibit wound healing. This study aimed to create animal models of chronic wound using topical MMC compared to those who given exposure of NaCl without topical MMC. This study used eight female Wistar rats aged 70 to 90 days, weighed between 300 to 350 grams. Wounds were made in the hip area with a diameter of approximately two centimeters. The subjects were divided into two groups. The first group, we compressed the wounds using sterile gauze moistened with MMC 0.5 mg/ml for 5 minutes and rinsed with a saline solution as much as 10 ml6. The second group was compressed using sterile gauze moistened with saline for 5 minutes. On day 3, 5, and 15 we observed the wound profile that was consist of diameter (as an indicator of wound healing), necrosis, and the consistency. The wounds that were compressed using MMC showed brownish-black, dry, thick chronic wounds and took longer to heal compared to those with NaCl. Application of MMC topically on the wound after day 15 showed an inhibition of wound healing process. The animal models showed a slower decrease of wound diameter, fewer scar tissue formation, and development of necrotic tissue.
Co-Authors Aditya Rifqi Fauzi Aditya Wicaksana Andreas Ariawan Anindhawati, Nur Atmodiwirjo, Parintosa Budiman Budiman Harsono, Anastasia Dessy Ishandono Dachlan Laureen Supit Mahandaru, Danu Pudjisriyani, Pudjisriyani Samiadji, Muhammad Suhartadi, Bayu Swantari, Ni Made Wahdini, Siti Isya Wicaksana, Aditya