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Rational Antibiotic Use by Ordinary People in Jakarta Sherly Tandi Arrang; Fonny Cokro; Erlia Anggrainy Sianipar
MITRA: Jurnal Pemberdayaan Masyarakat Vol 3 No 1 (2019): MITRA: Jurnal Pemberdayaan Masyarakat
Publisher : Institute for Research and Community Services

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/mitra.v3i1.502

Abstract

Self-medication is defined as self treatment and self-diagnose for conditions such as cough, flu, fever, pain, stomach ulcers, worms, diarrhea, rash, and some other minor illnesses. Based on the data from Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI (2013), there were 103.860 of 294.959 households (35,2%) in Indonesia which store medicines for selfmedication (including 35,7% “Obat Keras” or “Gevaarlijk” and 27,8% antibiotics). DKI Jakarta (56,4%) is the highest province with respect to stored medicines. Some studies have found that 40-62% of antibiotics are not used properly. The inappropriate use of antibiotics can lead to antibiotic resistance risk and can be life-threatening for people in every part of the world. To address this problem, this community service was conducted to provide information about selfmedication of influenza and cough illness and to improve people’s knowledge in the proper use of antibiotics. Lecturing was chosen as the method for explaining the rational use of antibiotics and participants were requested to fill out a questionnaire. This activity was attended by 34 participants (and 32 participants filled out the questionnaire). About 13 participants (40,6%) provided correct answers to questions on the proper use of antibiotics. Twenty six participants (81,25%) said they had previously used antibiotics, 14 of them (53,85%) admitted to purchasing antibiotics without a prescription. Antibiotics are taken to treat symptoms such as runny nose, cough, sore throat, fever, and other conditions. A total of 7 participants (26,92%) admitted taking antibiotics with dosage modification and 8 participants (30,77%) switched one type of antibiotics with another type of antibiotics. Based on the results, we concluded that people did not have sufficient knowledge about the rational use of antibiotics. We suggested that counseling about the proper use of antibiotics should be improved.
Drug Information Service during Covid-19 Pandemic Sherly Tandi Arrang; Reynelda Juliani Sagala; Dion Notario; Erlia Anggrainy Sianipar; Fonny Cokro
MITRA: Jurnal Pemberdayaan Masyarakat Vol 5 No 1 (2021): MITRA: Jurnal Pemberdayaan Masyarakat
Publisher : Institute for Research and Community Services

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/mitra.v5i1.1467

Abstract

Pharmacists and pharmaceutical personnel need to support improving the people’s quality of life during the covid-19 outbreak by providing pharmaceutical services, one of which is the Drug Information Service (PIO). Many regions in Indonesia, including DKI Jakarta, have placed large-scale social restrictions since March 2020. In connection with that, the Department of Pharmacy of Atma Jaya Catholic University of Indonesia (PSFUAJ) organized an online PIO program. This program aimed to provide the service of Covid-19 drug-related information and education to the community. The PIO was carried out from April to July 2020 via whatsapp, email, and telephone. In addition, health education was provided through e-flyers, published on Instagram @pio_farmasi_uaj. Eighty percent of the questions were submitted via whatsapp, while the rest was sent via email. Most of the questions submitted (80%) were categorized into self-edication. Further examination shows that the common questions were related to drug choice (27.78%). These data indicate that most questioners tend to provide self-medication first and that they will only see a doctor if they have not recovered or experienced any improvement. PSFUAJ will continue running this program and disseminating this program to a broader audience.
PENGUJIAN AKTIVITAS ANTIOKSIDAN MAKRO ALGA SUMBAWA DALAM HUBUNGANNYA DENGAN KANDUNGAN SENYAWA BIOAKTIF DAN EFEK FARMAKOLOGI Erlia Anggrainy Sianipar; Natasha Satriawan; Juliana Sumartono; Pretty Falena Atmanda Kambira
Jurnal Riset Kesehatan Nasional Vol. 6 No. 2 (2022)
Publisher : Institute Teknologi dan Kesehatan (ITEKES) Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37294/jrkn.v6i2.457

Abstract

Abstract A popular natural resource of Sumbawa Island is macroalgae. Chlorophyta, Phaeophyta, and Rhodophyta are types of macroalgae that have been cultivated and utilized by the local community. However, its potential to treat many diseases is still under-explored. Based on the content of bioactive compounds, macroalgae is believed to have antioxidant activity that could scavenge free radicals and thus potentially prevent and treat various diseases caused by excessive free radicals. This study aimed to analyze the antioxidant activity of Sumbawa macroalgae in various solvent fractions. Samples were macerated in n-hexane, ethyl acetate, and ethanol solvents. Antioxidant activity was tested using 1,1-Diphenyl-2-picryl Hydrazil (DPPH) method and ascorbic acid as a positive control. The percentage yield of extracts from various solvent fractions varied between 0.25% to 0.62%. The result of antioxidant activity testing showed that the IC50 (Inhibition Concentration) value of macroalgae extract was moderate to weak in the range of 108.1 ± 1.068 to 665.2 ± 0.479 g/mL and positive control was 6.156 ug/mL ±0.563g/mL. The relationship between antioxidant activity and the content of bioactive compounds and their pharmacological effects were discussed in this study. This study concluded that the ethyl acetate fraction of macroalgae had higher antioxidant activity than the n-hexane and ethanol fractions. Further analysis was needed to determine the composition of the bioactive compounds and identify their pharmacological effects at the molecular level.   Keywords: Macroalgae, antioxidant, Sumbawa, bioactive compounds, pharmacological effects   Abstrak Sumber daya alam yang populer di Pulau Sumbawa adalah makroalga. Chlorophyta, Phaeophyta dan Rhodophyta merupakan jenis makroalga yang telah dibudidayakan dan dimanfaatkan oleh masyarakat setempat. Namun, potensinya dalam hal pengobatan penyakit masih kurang tereksplorasi. Berdasarkan kandungan senyawa bioaktifnya, makroalga diyakini memiliki aktivitas antioksidan yang dapat menangkap radikal bebas sehingga berpotensi mencegah dan mengobati berbagai penyakit akibat radikal bebas yang berlebihan. Penelitian ini bertujuan untuk menganalisis aktivitas antioksidan makroalga Sumbawa dalam berbagai fraksi pelarut. Sampel dimaserasi dalam pelarut n-heksan, etil asetat, dan etanol. Aktivitas antioksidan diuji dengan metode 1,1-Diphenyl-2-picryl Hydrazil (DPPH) dan asam askorbat sebagai kontrol positif. Hasil persentase rendemen ekstrak dari berbagai fraksi pelarut cukup bervariasi berkisar antara 0,25% hingga 0,62%. Hasil pengujian aktivitas antioksidan menunjukkan nilai IC50 (Inhibition Concentration) ekstrak makroalga tergolong sedang hingga lemah yang berada dalam rentang 108,1 ± 1,068 hingga 665,2 ± 0,479 µg/mL dan kontrol positif sebesar 6,156 ug/mL ±0,563g/mL. Hubungan aktivitas antioksidan dengan kandungan senyawa bioaktif dan efek farmakologinya dibahas dalam penelitian ini. Penelitian ini menyimpulkan bahwa fraksi etil asetat makroalga memiliki aktivitas antioksidan yang lebih tinggi dibandingkan fraksi n-heksan dan etanol. Analisis lebih lanjut diperlukan untuk mengetahui komposisi senyawa bioaktif dan mengidentifikasi efek farmakologinya pada tingkat molekuler.   Kata Kunci: Makroalga, Antioksidan, Sumbawa, Senyawa Bioaktif, Efek farmakologi  
Education and Early Detection of Diabetes Mellitus Risk in North Jakarta Office Environment Erlia Anggrainy Sianipar; Monica Fransiska; Marisa Felicia; Alnardo Tuamain; Monika Angelina; Maria Gracia Mutiara Misesha; Sherly Tandi Arrang
Warta Pengabdian Andalas Vol 31 No 2 (2024)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.31.2.386-392.2024

Abstract

A low level of knowledge related to the causative factors, signs and symptoms, dangers, prevention, and treatment of diabetes mellitus (DM) causes an increasing number of DM sufferers worldwide, including in Indonesia. This community service activity aims to increase public knowledge, especially in the office environment, about DM disease and conduct early detection of DM. Participants in the community service activities consisted of 90 employees of an Accountant's office in North Jakarta. The community service activities included education about DM disease, tests of blood sugar, and question-and-answer discussions about DM. The results showed an increase in knowledge by 20.3% based on the score obtained from the pretest compared to the posttest. Based on the blood sugar test results, 98.9% of participants had blood sugar levels within normal limits, 1.1% were below average (hypoglycemia), and 1.1% were at risk of DM. This activity concludes that educational activities can increase participants' knowledge about DM disease, so it is hoped that the community can implement a healthy lifestyle to prevent DM disease and reduce the number of DM sufferers.