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Cokro, Fonny

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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Other

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The Impacts of Lifestyle Modification Education towards Cardiovascular Risk Profile Cokro, Fonny; Rahem, Abdul; Aditama, Lisa; Kristianto, Franciscus C.
Indonesian Journal of Clinical Pharmacy Vol 7, No 3 (2018)
Publisher : Indonesian Journal of Clinical Pharmacy

Obesity is one of the risk factors of cardiovascular disease. The prevalence of obesity in Indonesia has increased in the last few years, therefore some efforts to reduce the risk is needed. In the current study, efforts are given through 3-week lifestyle modification education, with 3-month total of follow-up (from March to June 2014) and then the impacts on cardiovascular risk profile were observed and seen on 24 sedentary male workers in University of Surabaya with obese II. This study used before-after study design in order to see the impacts of the 3-week lifestyle modification education towards change of knowledge, dietary behavior, body mass index (BMI), waist circumference, and cardiovascular risk profile through various educational methods (face-to-face session, given recorder of face-to-face session, and combination of both methods). Statistical analysis was performed using Wilcoxon signed test. Result showed an increasing knowledge in face-to-face group (p=0.046). However, there were no significant changes in other variables (dietary behavior based on healthy diet indicator (HDI), BMI, waist circumference, and also cardiovascular risk profile) in all groups between before and after education intervention (p>0.05). In conclusion, lifestyle modification education given for 3 weeks did not reduce the cardiovascular risk profile on sedentary male workers with obese II. Longer term intervention and multicomponent program including behavior therapy may be needed to succeed lifestyle changes and reduce cardiovascular risk.Keywords: Behaviour, cardiovascular risk, education, knowledge, lifestyle modificationÂ Pengaruh Edukasi Gaya Hidup terhadap Perubahan Risiko Penyakit KardiovaskularAbstrakObesitas merupakan salah satu faktor risiko penyakit kardiovaskular. Prevalensi obesitas di Indonesia mengalami peningkatan beberapa tahun terakhir, sehingga diperlukan upaya untuk menguranginya. Pada penelitian ini, upaya dilakukan melalui pemberian edukasi gaya hidup yang dilakukan selama 3 minggu, dengan total follow-up sampai dengan 3 bulan dari bulan Maret hingga Juni 2014, kemudian dilihat dan diamati ada atau tidaknya penurunan risiko penyakit kardiovaskular pada 24 orang karyawan pria obese II di Universitas Surabaya. Penelitian ini memiliki rancangan before-after study design untuk menguji pengaruh edukasi gaya hidup yang diberikan selama 3 minggu terhadap variabel pengetahuan, perubahan perilaku, body mass index (BMI), lingkar perut, dan risiko penyakit kardiovaskular melalui berbagai metode pemberian edukasi (tatap muka, rekaman/recorder, dan kombinasi). Analisis dengan Wilcoxon signed test menunjukkan bahwa terdapat peningkatan pengetahuan hanya pada subgrup tatap muka (p=0,046). Tidak terdapat perubahan yang signifikan terhadap variabel lainnya (perubahan perilaku berdasarkan healthy diet indicator (HDI), BMI dan lingkar perut, serta risiko penyakit kardiovaskular) pada semua subgrup antara sebelum dan sesudah edukasi (p>0,05). Edukasi gaya hidup yang diberikan selama tiga minggu tidak memberikan penurunan risiko penyakit kardiovaskular pada karyawan pria obese II. Dibutuhkan intervensi jangka panjang dan program multikomponen yang memuat terapi perilaku untuk menyukseskan perubahan perilaku dan menurunkan risiko kardiovaskular.Kata kunci: Edukasi, gaya hidup, pengetahuan, perilaku, risiko kardiovaskular

The Impacts of Lifestyle Modification Education towards Cardiovascular Risk Profile Fonny Cokro; Abdul Rahem; Lisa Aditama; Franciscus C. Kristianto
Indonesian Journal of Clinical Pharmacy Vol 7, No 3 (2018)
Publisher : Universitas Padjadjaran

Obesity is one of the risk factors of cardiovascular disease. The prevalence of obesity in Indonesia has increased in the last few years, therefore some efforts to reduce the risk is needed. In the current study, efforts are given through 3-week lifestyle modification education, with 3-month total of follow-up (from March to June 2014) and then the impacts on cardiovascular risk profile were observed and seen on 24 sedentary male workers in University of Surabaya with obese II. This study used before-after study design in order to see the impacts of the 3-week lifestyle modification education towards change of knowledge, dietary behavior, body mass index (BMI), waist circumference, and cardiovascular risk profile through various educational methods (face-to-face session, given recorder of face-to-face session, and combination of both methods). Statistical analysis was performed using Wilcoxon signed test. Result showed an increasing knowledge in face-to-face group (p=0.046). However, there were no significant changes in other variables (dietary behavior based on healthy diet indicator (HDI), BMI, waist circumference, and also cardiovascular risk profile) in all groups between before and after education intervention (p>0.05). In conclusion, lifestyle modification education given for 3 weeks did not reduce the cardiovascular risk profile on sedentary male workers with obese II. Longer term intervention and multicomponent program including behavior therapy may be needed to succeed lifestyle changes and reduce cardiovascular risk.Keywords: Behaviour, cardiovascular risk, education, knowledge, lifestyle modification Pengaruh Edukasi Gaya Hidup terhadap Perubahan Risiko Penyakit KardiovaskularAbstrakObesitas merupakan salah satu faktor risiko penyakit kardiovaskular. Prevalensi obesitas di Indonesia mengalami peningkatan beberapa tahun terakhir, sehingga diperlukan upaya untuk menguranginya. Pada penelitian ini, upaya dilakukan melalui pemberian edukasi gaya hidup yang dilakukan selama 3 minggu, dengan total follow-up sampai dengan 3 bulan dari bulan Maret hingga Juni 2014, kemudian dilihat dan diamati ada atau tidaknya penurunan risiko penyakit kardiovaskular pada 24 orang karyawan pria obese II di Universitas Surabaya. Penelitian ini memiliki rancangan before-after study design untuk menguji pengaruh edukasi gaya hidup yang diberikan selama 3 minggu terhadap variabel pengetahuan, perubahan perilaku, body mass index (BMI), lingkar perut, dan risiko penyakit kardiovaskular melalui berbagai metode pemberian edukasi (tatap muka, rekaman/recorder, dan kombinasi). Analisis dengan Wilcoxon signed test menunjukkan bahwa terdapat peningkatan pengetahuan hanya pada subgrup tatap muka (p=0,046). Tidak terdapat perubahan yang signifikan terhadap variabel lainnya (perubahan perilaku berdasarkan healthy diet indicator (HDI), BMI dan lingkar perut, serta risiko penyakit kardiovaskular) pada semua subgrup antara sebelum dan sesudah edukasi (p>0,05). Edukasi gaya hidup yang diberikan selama tiga minggu tidak memberikan penurunan risiko penyakit kardiovaskular pada karyawan pria obese II. Dibutuhkan intervensi jangka panjang dan program multikomponen yang memuat terapi perilaku untuk menyukseskan perubahan perilaku dan menurunkan risiko kardiovaskular.Kata kunci: Edukasi, gaya hidup, pengetahuan, perilaku, risiko kardiovaskular

The Beyond-Use Date Perception of Drugs in North Jakarta, Indonesia Fonny Cokro; Sherly T. Arrang; Jonathan A. N. Solang; Pangestuning Sekarsari
Indonesian Journal of Clinical Pharmacy Vol 10, No 3 (2021)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2021.10.3.172

Beyond-Use Date (BUD) refers to the unsafe period of drug consumption and is calculated from the moment of opening the primary package. Meanwhile, Indonesia has no current related data, in terms of public awareness. Therefore, this research aims to assess the BUD perception of North Jakarta communities and pharmacists’ roles in providing the relevant information. The data collection process employed a semi-structural interview across 6 districts in the research location between September-November 2019, followed by data transcription and thematic development. Based on 60 informants recruited by purposive sampling, three themes were obtained, including residual drug storage, pharmacists’ contributions, and BUD awareness. Furthermore, about 97% of the respondents were completely unaware of the subject matter, while 100% denied having any form of sensitization from pharmacists. The perception of 50% were based on the expiration date labelled on the medications. In summary, North Jakarta community’s views were possibly influenced by very poor BUD knowledge. Therefore, the role of pharmacists in educating patients and communities appears very essential.Keywords: Drug-compounding, drug-stabilities, perception, pharmacists Persepsi mengenai Beyond-Use Date Obat pada Masyarakat Jakarta Utara, IndonesiaAbstrakBeyond-Use Date (BUD) merupakan waktu ketika sediaan obat tidak dapat digunakan lagi dan dihitung berdasarkan waktu pembukaan kemasan primer sediaan. Sampai dengan saat ini, tidak terdapat data tentang pemahaman masyarakat Indonesia mengenai BUD. Penelitian ini bertujuan untuk melihat persepsi masyarakat Jakarta Utara mengenai BUD, serta mengetahui peran apoteker dalam menyediakan informasi BUD. Data mengenai persepsi BUD diperoleh dari wawancara semi terstruktur yang dilakukan di 6 kecamatan yang terletak di Jakarta Utara pada September–November 2019, dan diikuti oleh proses transkripsi dan pengembangan tema. Dari 60 informan yang direkrut secara purposive sampling, didapatkan tiga tema yaitu penyimpanan sisa obat racikan, kontribusi apoteker terkait BUD, dan pengenalan terhadap BUD. Mayoritas informan (97%) tidak mengetahui tentang BUD, dan semua informan (100%) tidak pernah menerima informasi BUD dari apoteker. Sebagian dari informan memiliki persepsi bahwa BUD sama dengan masa kadaluarsa yang ada di kemasan pabrik. Kami menyimpulkan bahwa persepsi masyakat Jakarta Utara mengenai BUD dapat disebabkan oleh pengetahuan tentang BUD yang rendah, dan peran apoteker dalam menginformasikan dan mengedukasi pasien dan masyarakat mengenai BUD sangat diperlukan. Kata kunci: Apoteker, obat racikan, persepsi, stabilitas obat

Efektivitas Flukonazol dalam Mencegah Infeksi Jamur Invasif pada Bayi dengan Berat Lahir Sangat Rendah: Tinjauan Sistematis dan Meta-analisis Fonny Cokro; Lorensia Yolanda; Shelly Caroline
JURNAL ILMU KEFARMASIAN INDONESIA Vol 20 No 1 (2022): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v20i1.1035

Fungal infections in neonates, especially in Very Low Birth Weight (VLBW) infants, are mostly caused by Candida species and may lead to morbidity and mortality. A systematic review and a meta-analysis were conducted to determine the extent to which fluconazole, an antifungal prophylactic, was effective and safe to use in VLBW or premature infants in preventing Invasive Fungal Infection (IFI), by including Randomized Controlled Trials (RCTs) carried out worldwide. The investigation started with searching process through publication databases: MEDLINE, Cochrane, ScienceDirect, and Garuda, for Randomized Controlled Trials (RCTs) that compared the prophylactic effects of fluconazole and placebo on IFI in VLBW infants. The selected eight RCT studies indicated that, compared to placebo, fluconazole accounted for 68% risk reduction of overall fungal colonization (RR=0.32; 95% confidence interval [CI]=0.24-0.42, p=0.00001, I-square=0%) and 60% risk reduction of IFI (RR=0.40; 95%[CI]=0.22-0.72, I-square=56%, p=0.002). However, fluconazole did not significantly reduce mortality in VLBW infants (RR=0.79; 95%[CI]=0.60-1.03; p=0.08, I-square=0%). Also, regarding its safety, fluconazole prophylaxis did not result in significant elevations of SGOT/SGPT levels (RR=1.22; 95%[CI]=0.50-3.00, p=0.66, I-square=0%) nor cause intestinal perforation (RR=0.96; 95%[CI]=0.25-3.68, p=0.96, I-square=59%). Fluconazole is an effective prophylaxis agent against invasive fungal infection when given to preterm infants with birth weight <1500, but not proven in reducing the mortality incidence in VLBW infants.

Rational Antibiotic Use by Ordinary People in Jakarta Sherly Tandi Arrang; Fonny Cokro; Erlia Anggrainy Sianipar
MITRA: Jurnal Pemberdayaan Masyarakat Vol 3 No 1 (2019): MITRA: Jurnal Pemberdayaan Masyarakat
Publisher : Institute for Research and Community Services

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/mitra.v3i1.502

Self-medication is defined as self treatment and self-diagnose for conditions such as cough, flu, fever, pain, stomach ulcers, worms, diarrhea, rash, and some other minor illnesses. Based on the data from Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI (2013), there were 103.860 of 294.959 households (35,2%) in Indonesia which store medicines for selfmedication (including 35,7% “Obat Keras” or “Gevaarlijk” and 27,8% antibiotics). DKI Jakarta (56,4%) is the highest province with respect to stored medicines. Some studies have found that 40-62% of antibiotics are not used properly. The inappropriate use of antibiotics can lead to antibiotic resistance risk and can be life-threatening for people in every part of the world. To address this problem, this community service was conducted to provide information about selfmedication of influenza and cough illness and to improve people’s knowledge in the proper use of antibiotics. Lecturing was chosen as the method for explaining the rational use of antibiotics and participants were requested to fill out a questionnaire. This activity was attended by 34 participants (and 32 participants filled out the questionnaire). About 13 participants (40,6%) provided correct answers to questions on the proper use of antibiotics. Twenty six participants (81,25%) said they had previously used antibiotics, 14 of them (53,85%) admitted to purchasing antibiotics without a prescription. Antibiotics are taken to treat symptoms such as runny nose, cough, sore throat, fever, and other conditions. A total of 7 participants (26,92%) admitted taking antibiotics with dosage modification and 8 participants (30,77%) switched one type of antibiotics with another type of antibiotics. Based on the results, we concluded that people did not have sufficient knowledge about the rational use of antibiotics. We suggested that counseling about the proper use of antibiotics should be improved.

Drug Information Service during Covid-19 Pandemic Sherly Tandi Arrang; Reynelda Juliani Sagala; Dion Notario; Erlia Anggrainy Sianipar; Fonny Cokro
MITRA: Jurnal Pemberdayaan Masyarakat Vol 5 No 1 (2021): MITRA: Jurnal Pemberdayaan Masyarakat
Publisher : Institute for Research and Community Services

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/mitra.v5i1.1467

Pharmacists and pharmaceutical personnel need to support improving the people’s quality of life during the covid-19 outbreak by providing pharmaceutical services, one of which is the Drug Information Service (PIO). Many regions in Indonesia, including DKI Jakarta, have placed large-scale social restrictions since March 2020. In connection with that, the Department of Pharmacy of Atma Jaya Catholic University of Indonesia (PSFUAJ) organized an online PIO program. This program aimed to provide the service of Covid-19 drug-related information and education to the community. The PIO was carried out from April to July 2020 via whatsapp, email, and telephone. In addition, health education was provided through e-flyers, published on Instagram @pio_farmasi_uaj. Eighty percent of the questions were submitted via whatsapp, while the rest was sent via email. Most of the questions submitted (80%) were categorized into self-edication. Further examination shows that the common questions were related to drug choice (27.78%). These data indicate that most questioners tend to provide self-medication first and that they will only see a doctor if they have not recovered or experienced any improvement. PSFUAJ will continue running this program and disseminating this program to a broader audience.

The Online Seminar on the Effects of Metabolic Syndrome on Covid-19 Patients among Urban Communities Fonny Cokro; Nathacia Nathacia; Meilani Eka Putri; Genoveva Della; Felicia Christian
MITRA: Jurnal Pemberdayaan Masyarakat Vol 6 No 1 (2022): MITRA: Jurnal Pemberdayaan Masyarakat
Publisher : Institute for Research and Community Services

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/mitra.v6i1.2253

Metabolic syndrome is typically characterized by hypertension, diabetes mellitus, dyslipidemia, and obesity—all of which can contribute to a higher risk of acute coronary syndrome (ACS). Mounting evidence also shows how metabolic syndrome may lead to worsening symptoms in covid-19 patients, thus resulting in more fatal cases. Therefore, what is urgently needed is the efforts to improve public awareness of the adverse effects of metabolic syndrome on covid-19 patients and the importance of health protocols against covid-19 transmission. An online seminar via zoom was held to support the fight against the covid-19 pandemic among the urban communities, which were chosen due to the prevalence of metabolic syndrome in these communities. The two-hour online counseling was also held to commemorate World Pharmacist Day, which fell on September 26, 2020. The responses to the questionnaire revealed that the majority of participants had a better understanding of the metabolic syndrome, its risks, its detrimental influence on the conditions of covid-19 patients, and the efforts to prevent Covid-19 transmissions. The seminar is expected to contribute to the government’s efforts to bolster the community’s awareness of the importance of health protocols

Effectiveness of Proton Pump Inhibitors as a Gastrointestinal Bleeding Prophylaxis in Intensive Care Unit: Systematic Review and Meta-Analysis Fonny Cokro; Jenny Jokimawidjaja
Journal of Urban Health Research Vol. 1 No. 1 (2022): Journal of Urban Health Research
Publisher : School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/juhr.v1i1.3714

Introduction: GI bleeding is a serious illness that can lengthen the time spent in the Intensive Care Unit (ICU) and increase morbidity and death by up to four times. Proton Pump Inhibitors (PPIs) are agents commonly used in patients to prevent Gastrointestinal (GI) bleeding in ICU. However, nowadays, the use of PPIs to prevent GI bleeding is being concerned due to the emergence of various studies regarding the side effects caused by PPIs. We conducted a systematic review and meta-analysis to see the magnitude of the effectiveness and validate the safety of PPIs. Methods: We searched through PubMed, ScienceDirect, GARUDA Portal, Clinical Key, and Google Scholar databases to identify randomized controlled trials (RCTs) that compared the effects of PPI administration on the PPI and placebo groups in adults ICU patients. Results: From a total of 8 studies, this meta-analysis shows the effectiveness of PPIs as prophylactic GI bleeding significantly with p < 0.0001, RR = 0.52 (95% CI 0.38-0.71). Regarding safety, PPIs did not significantly increase the risk of pneumonia (p = 0.30, RR = 1.31 (95% CI 0.78-2.20)); and C. difficile infection (p = 0.90, RR = 0.91 (95% CI 0.21-3.85); and it does not impact on the mortality event (p = 0.78; RR 1.01 (95% CI 0.93-1.10). Conclusions: PPIs reduce GI bleeding in ICU patients over the age of 18. PPIs are also safe to use as preventative GI bleeding with no increased risk of pneumonia and C. difficile infection. PPI does not, however, significantly affect the death rates.

Analysis of specialist doctors' behavior towards SGLT2 inhibitors prescription in Indonesia: A qualitative study Cokro, Fonny; Sauriasari, Rani; Tahapary, Dicky L.; Setiawan, Heri; Martha, Evi
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.2089

Sodium-glucose cotransporter-2 inhibitors (SGLT2is) have a broad range of clinical indications and are recommended by various guidelines for the management of diabetes, heart failure, and chronic kidney disease. However, prescribing rates for these agents are suboptimal towards various intended indications in many countries, including Indonesia. The aim of this study was to analyze the prescribing practices of SGLT2is among endocrinologists, cardiologists, and nephrologists in Indonesia. A qualitative method was utilized to provide a comprehensive understanding of this phenomenon. Semi-structured online interviews were performed with 18 participants, comprising seven specialized doctors as primary informants; eight key informants representing pharmacies, governmental bodies, and pharmaceutical marketing representatives; and three patients as supplementary informants. Furthermore, closed observations of two specialist doctors were undertaken as an additional data collection method. Informants were recruited using criterion and snowball sampling methods. The Theoretical Domains Framework was used as an interview guide; all interviews were audio visual-recorded, transcribed verbatim, and subsequently analyzed for thematic content with NVivo version 12. Seven themes emerged concerning the prescribing behavior of SGLT2is: socioeconomic status, therapeutic rationality, utilization barriers, utilization optimization, the urge to prescribe, therapeutic expectations and targets, and aspects of the health system and ethical considerations. Most informants possessed favorable perspectives regarding using SGLT2is when prescribed appropriately, yet specific elements necessitate enhancement to refine therapeutic justification, including initiatives to incorporate SGLT2is into the national formulary.

Upaya Pencegahan Risiko COVID-19 Gejala Berat dan Sindroma Metabolik Melalui Pemeriksaan Kesehatan dan Edukasi Masyarakat di Rusunawa Penjaringan, Jakarta Utara Cokro, Fonny; Nurcahyanti, Agustina Dwi Retno; Andrelia, Evelyn Trisia; Pattirajawane, Ignatius Danny
Abdimas Galuh Vol 7, No 1 (2025): Maret 2025
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v7i1.16610

Sindroma metabolik merupakan serangkaian faktor risiko yang dapat meningkatkan risiko kejadian penyakit kardiovaskular dan diabetes mellitus tipe 2. Berbagai penelitian menunjukkan bahwa diabetes, hipertensi, dan obesitas berkontribusi terhadap perburukan gejala COVID-19. Kegiatan pengabdian ini bertujuan untuk memberikan edukasi tentang sindroma metabolik, pentingnya gaya hidup sehat untuk preventifnya, serta fungsi kepatuhan terapi dan pengawasan pada para penyadang sindroma metabolik, di samping pentingnya protokol kesehatan untuk menghindari paparan virus COVID-19 dengan derajat keparahan tinggi. Studi cross-sectional dilakukan di Kecamatan Penjaringan, Jakarta Utara, khususnya pada komunitas rusunawa, melibatkan 42 peserta edukasi dan 28 peserta yang mengikuti pemeriksaan kesehatan. Untuk mengevaluasi peningkatan pengetahuan peserta mengenai konten edukasi, kuesioner pengetahuan diberikan pada saat sebelum dan sesudah kegiatan. Pemeriksaan kesehatan yang dilakukan menemukan tingkat obesitas sentral (89%), peningkatan tekanan darah (46,43%), dan peningkatan kadar gula darah (67,86%) di antara para peserta. Melalui analisis statistik menggunakan uji-t berpasangan, terjadi peningkatan signifikan pada pengetahuan peserta (56,58% sebelum pendidikan dibandingkan dengan 67,67% setelah pendidikan; p = 0,00). Temuan ini menunjukkan bahwa intervensi pendidikan berhasil meningkatkan pengetahuan peserta, dan menggarisbawahi pentingnya mempromosikan gaya hidup sehat.

Co-Authors Abdul Rahem Abdul Rahem, Abdul Agnes Anania Triavika Sahamastuti Agustina Dwi Retno Nurcahyanti Andrelia, Evelyn Trisia Anton Sumarpo Arrang, Sherly Tandi Dion Notario Erlia Anggrainy Sianipar Evi Martha Felicia Christian Franciscus C. Kristianto Genoveva Della Gokok, Silvia Gunawan, Catherine Keiko Heri setiawan Jap, Adeline Jenny Jokimawidjaja Jonathan A. N. Solang Kristianto, Franciscus C. Lady, Jullietta Lisa Aditama, Lisa Lorensia Yolanda Meilani Eka Putri Nathacia Nathacia Pangestuning Sekarsari Pattirajawane, Ignatius Danny Rani Sauriasari, Rani Sagala, Reynelda Juliani Shelly Caroline Sherly T. Arrang Tahapary, Dicky L. Yolanda, Lorensia

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