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All Journal JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Insan Farmasi Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Innovation Research and Knowledge Medical Sains : Jurnal Ilmiah Kefarmasian
Raudatul Patimah
Fakultas Farmasi, Universitas Muhammadiyah Banjarmasin
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Physics Social Sciences

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Journal : Jurnal Insan Farmasi Indonesia

 1 
THE ISOLATION OF α-CELLULOSE & THE PREPARATION OF MICROCRYSTALLINE CELLULOSE FROM SOURSOP LEAVES (Annona muricata L.) Yulianita Pratiwi Indah Lestari; Mi'rajunnisa; Raudatul Patimah
Jurnal Insan Farmasi Indonesia Vol 6 No 1 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i1.1298

Abstract

Powder characteristics are very important to consider in the tablet manufacturing process because they can affect the characteristics of the resulting tablets. This study aims to determine the characteristics of microcrystalline cellulose powder isolated from soursop leaves. This research method includes preparation of soursop leaves raw material, isolation of α-cellulose using 17.5% NaOH solution with 3.5% nitric acid (containing 20 mg sodium nitrite), manufacture of microcrystalline cellulose using 1 M HCl solution, and characterization of microcrystalline cellulose including quality checks. powder (organoleptic, identification, solubility), and pH testing. The results showed that the yield of microcrystalline cellulose (MCCDSr) was 96.59% against α-cellulose. The results of the characterization of microcrystalline cellulose powder including organoleptic, identification, solubility, melting point, and pH showed similar characteristics with Avicel® PH 101 as a comparison. Based on the research that has been done, the characteristics of microcrystalline cellulose powder from soursop leaves are similar to Avicel® PH 101.
Co-Authors Aris Purwanto Esti Hendradi Isnaeni Isnaeni Kurnia Mi'rajunnisa Mustika Muthaharah Nor Latifah Rizka Mulya Miranti Sofia Nabila Safitri Tuty Tuty Mulyani Yulianita Pratiwi Indah Lestari