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All Journal Medical Journal of Indonesia Indonesian Journal of Cancer

Sudigdo Sastroasmoro

Department of Child Health, Medical School, Universitas Indonesia, Jakarta.

Author-ID : 374278

Health Professions Medicine & Pharmacology

Published : 11 Documents Claim Missing Document

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Survival patterns of children with rheumatic heart disease Sastroasmoro, Sudigdo; Madiyono, Bambang; Oesman, Ismet N.; Putra, Sukman T.; Advani, Najib
Medical Journal of Indonesia Vol 4, No 4 (1995): October-December
Publisher : Faculty of Medicine Universitas Indonesia

[no abstract available]

Treadmill test in patients with rheumatic mitral regurgitation Madiyono, Bambang; Rusdi, Sabiqun; Oesman, Ismet N.; Sastroasmoro, Sudigdo; Putra, Sukman T.; Advani, Najib
Medical Journal of Indonesia Vol 4, No 4 (1995): October-December
Publisher : Faculty of Medicine Universitas Indonesia

[no abstract available]

Research Report Writing Sastroasmoro, Sudigdo
Indonesian Journal of Cancer Vol 3, No 5 (2009): Workshops 2009
Publisher : "Dharmais" Cancer Center Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar

https://www.scribd.com/doc/45478236/Research-Report-Writing

Effects of dobutamine on ventricular functions and cerebral blood flow in preterm infants with mild hyaline membrane disease Sastroasmoro, Sudigdo
Medical Journal of Indonesia Vol 7, No 4 (1998): October-December
Publisher : Faculty of Medicine Universitas Indonesia

[no abstract available]

Effect of dobutamine on the clinical course of preterm infants with mild hyaline membrane disease Sastroasmoro, Sudigdo
Medical Journal of Indonesia Vol 7, No 4 (1998): October-December
Publisher : Faculty of Medicine Universitas Indonesia

[no abstract available]

Clinical features and management of secundum atrial septal defect in infants and children Madiyono, Bambang; Achmad, Jumiety; Sastroasmoro, Sudigdo; Oesman, Ismet N.; Putra, Sukman T.
Medical Journal of Indonesia Vol 5, No 1 (1996): January-March
Publisher : Faculty of Medicine Universitas Indonesia

[no abstract available]

Profile and prediction of severity of rheumatic mitral stenosis in children Oesman, Ismet N.; Gunardi, Hartono; Madiyono, Bambang; Sastroasmoro, Sudigdo; Putra, Sukman T.
Medical Journal of Indonesia Vol 5, No 3 (1996): July-September
Publisher : Faculty of Medicine Universitas Indonesia

[no abstract available]

The effect of Bifidobacterium animalis lactis HNO19 supplementation among pregnant and lactating women on interleukin-8 level in breast milk and infant’s gut mucosal integrity Dewanto, Naomi E.F.; Firmansyah, Agus; Sungkar, Ali; Dharmasetiawani, Nani; Sastroasmoro, Sudigdo; Kresno, Siti B.; Suradi, Rulina; Bardosono, Saptawati; Prasetyo, Dwi
Medical Journal of Indonesia Vol 26, No 3 (2017): September
Publisher : Faculty of Medicine Universitas Indonesia

Background: Newborn’s gut mucosal is not fully developed, therefore infants are prone to diarrhea. Probiotic supplementation is known to induce the gut mucosal maturity. This study aimed to identify whether probiotics supplementation among pregnant women since the third trimester would increase the infant’s gut mucosal integrity.Methods: A double-blind, randomized clinical trial was conducted to understand the potential effect of probiotic supplementation on the level of probiotics and IL-8 in breastmilk, urine IFABP, faecal α-1-antytripsin (AAT) and calprotectin in infant’s at birth (V0) and three-months old (V3). A single strain of Bifidobacterium lactis animalis HNO19 (known as DR10) was used since it was not the resident bacteria. The study was held at Budi Kemuliaan Hospital and its satellite clinics from December 2014 to December 2015.Results: About 14% (5/35) and 20% (7/35) of the subjects had DR10 in the breastmilk’s colostrum and at the age of 3-months. The median values of IL-8 in the probiotic group vs the placebo group at V0 and V3 were 2810,1 pg/mL vs 1516.4 pg/mL (p=0.327) and 173.2 pg/mL vs 132.7 pg/mL (p=0.211) respectively. IFABP level 211.7 ng/mL vs 842.5 ng/mL (p=0.243) and 25.3 ng/mL vs 25.1 ng/mL (p=0.466); AAT 136.2 mg/dL vs 148.1 mg/dL (p=0.466) and 24 mg/mL vs 29.72 mg/mL (p=0.545); Calprotectin 746.8 ng/mL vs 4645.2 ng/mL (p=0.233) and 378.6 ng/mL vs 391.3 ng/mL (p=0.888).Conclusion: Probiotic DR10 given to pregnant women since the 3rd trimester can be found in colostrum and 3-months breastmilk. However, it did not affect the level of other probiotics or IL-8 and the gut mucosal integrity.

Applicability of a clinical scoring criteria for disease severity of ß-thalassemia/hemoglobin E in Indonesia Wahidiyat, Pustika A.; Sastroasmoro, Sudigdo; Fucharoen, Suthat; Setianingsih, Iswari; Putriasih, Siti A.
Medical Journal of Indonesia Vol 27, No 1 (2018): March
Publisher : Faculty of Medicine Universitas Indonesia

Background: β-thalassemia/HbE presents with a variety of clinical symptoms, from asymptomatic to severe, requiring routine transfusion. However, there is currently no agreed classification system to stratify patients based on clinical severity of β-thalassemia/HbE in the Indonesian population. Thailand has already established a classification system, and this study aimed to identify the applicability of the Thailand clinical scoring criteria to determine the severity of β-thalassemia/HbE in the Indonesian population.Methods: This descriptive study was conducted by evaluating patients with β-thalassemia/HbE, who were classified into mild, moderate, or severe groups based on the Thailand clinical scoring criteria.Results: A total of 293 subjects with β-thalassemia/HbE were included. Based on this clinical scoring criteria, it was found that only 21.5% of patients were classified as mild, and the remaining 35.5% and 44% were classified as moderate and severe respectively. Approximately 68.2% of the subjects in the severe group received transfusion at <4 years old, while only 10% of those in the mild group were transfused at the same age. In the mild group, only 10% of the subjects underwent routine transfusion, compared to 98.4% of the subjects in the severe group. In addition, only 27% of the subjects in the mild group showed stunted growth, while that in the moderate and severe groups were 54.5% and 86.8%, respectively.Conclusion: Thailand clinical scoring criteria is able to determine the severity of Indonesia thalassemia patient which needs further management, i.e. transfusion and observation of stunted growth. This scoring system will help provide the provision of the most ideal management for the groups of patients based on their requirements.

MMP-9, brain edema, and length of hospital stay of patients with spontaneous supratentorial intracerebral hemorrhage after hematoma evacuation along with the administration of tigecycline Saekhu, Mohamad; Ibrahim, Nurhadi; Timan, Ina S.; Madjid, Amir S.; Muttaqin, Zainal; Ronokusumo, Teguh A.S.; Sastroasmoro, Sudigdo; Mahyuddin, Hilman
Medical Journal of Indonesia Vol 25, No 4 (2016): December
Publisher : Faculty of Medicine Universitas Indonesia

Background: The high plasma level of matrix metalloproteinses–9 (MMP-9) is believed to disrupt the blood-brain barrier (BBB) and cause brain edema, as well as increase patient’s length of hospital stay (LOS). Tigecycline showed ability to reduce the MMP-9 level on study in animals. This study aimed to evaluate whether tigecycline can reduce the plasma levels of MMP-9; brain edema; and LOS of patients with supratentorial spontaneous intracerebral hemorrhage (SSICH).Methods: A randomized clinical trial (RCT) was conducted on 72 SSICH patients who underwent hematoma evacuation in eleven hospitals in Jakarta; 100 mg tigecycline (n=35) or 2 g fosfomycine (n=37) administered intravenously before skin incision as an prophylactic antibiotics to avoid post-operative infections. Plasma levels of MMP-9 were measured in all subjects before and on the first and seventh day after the surgery. Reduction of brain edema was assessed by comparing the extent of brain edema on computed tomography scan (CT scan) before and CT scan after surgery. The length of stay (LOS) was recorded at the time of hospital discharge either survive or death. Data were analyzed using Mann-Whitney and Chi-Square test.Results: There were non-significant statistical differences between two groups in the proportion of subjects with reduced MMP-9 levels on the first day (48% vs 50%; p=0.902; OR=1.1) and seventh day after the surgery (33% vs 48%; p=0.296; OR=1.9); proportion of the subjects with brain edema reduction (86% vs 80%, p=0.58); LOS (median 12 days vs 13 days, p=0.256; LOS ≥15 days 40% vs 27%; p=0.243; OR=1.81; NNT=8).Conclusion: On SSICH patients who underwent hematoma evacuation, tigecycline did not either reduce MMP-9 levels and brain edema or shorthen LOS.

Co-Authors A.A. Ketut Agung Cahyawan W Agus Firmansyah Ali Sungkar Amir S. Madjid, Amir S. Bambang Madiyono Dewanto, Naomi E.F. Dwi Prasetyo Fucharoen, Suthat Hartono Gunardi Ina S. Timan, Ina S. Ismet N. Oesman Iswari Setianingsih Jumiety Achmad Mahyuddin, Hilman Mohamad Saekhu Mulyadi M Djer, Mulyadi M Najib Advani Nani Dharmasetiawani Nikmah S Idris, Nikmah S Nurhadi Ibrahim Pustika A. Wahidiyat Putriasih, Siti A. Ronokusumo, Teguh A.S. Ronokusumo, Tegus A.S. Rulina Suradi, Rulina Sabiqun Rusdi Saptawati Bardosono Siti B. Kresno Sukman T. Putra Sukman Tulus Putra, Sukman Tulus

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