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All Journal PHARMACON Universa Medicina
Hardy Senjaya
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Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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A 55 year old man with progressive neurologic deficits Muljadi, Sendjaja; Senjaya, Hardy
Universa Medicina Vol 28, No 2 (2009)
Publisher : Faculty of Medicine, Trisakti University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2009.v28.127-132

Abstract

At least 50 percent of the decline in functional abilities associated with the elderly is caused by neurological conditions, particularly vascular dementia, such as occurs in Binswanger disease. Binswanger disease is a rare condition, characterized by acute strokes with symptoms and signs compatible with lacunar infarction. The disease onset is commonly between 55 and 75 years. The majority of patients with Binswanger disease have chronic hypertension and other putative factors including diabetes mellitus, polycythemia, thrombocytosis, hyperlipidemia, hyperglobulinemia and pseudoxanthoma elasticum, increased fibrinogen levels and the antiphospholipid antibody syndrome. We report the case of a 55 year-old man, who suffered from involuntary movements of his right arm, slight hemiparesis on the right side, and also had dementia. He had a history of high blood pressure and laboratory tests showed that he had diabetes mellitus. The brain magnetic resonance imaging showed irregular white matter abnormalities with multiple lacunar infarcts in the basal ganglia and pons. The clinical picture is characterized by acute strokes, followed by involuntary movements and also dementia. Therefore we decided to diagnose it as Binswanger disease. After discharge from hospital, the patient has not returned for follow-up.
FORMULASI SALEP ANTIBAKTERI EKSTRAK ETANOL DAUN TEMBELEKAN (LANTANA CAMARA L) Parwanto, ML Edy; Senjaya, Hardy; Edy, Hosea Jaya
PHARMACON Vol 2, No 3 (2013): pharmacon
Publisher : PHARMACON

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Abstract

Tembelekan (Lantana camara L) is a wild plant that its leaves contain chemicals such asphenols, flavonoids and alkaloids. Chemical constituents in tembelekan allegedly hasantibacterial ability against Staphylococcus epidermidis. This research aims to create anantibacterial ointment to the active substance ethanol extract of leaves tembelekan.Antibacterial ointment tembelekan ethanol extract of the leaves made in two concentrations,namely 20% and 24%. Conducted quality testing ointment is organoleptic test, homogeneitytest, test and test pH value dispersive power. Quality test results conducted on theconcentration ointment with two parameters meet the organoleptic test, test and test pH valuehomogeneity. Tembelekan leaf extract ointment ethanol concentration of 20% and 24% didnot meet the quality parameters to test dispersive power.Keywords: Ethanol Leaf Extract tembelekan, ointments, test quality.
Co-Authors Hosea Jaya Edy ML Edy Parwanto Sendjaja Muljadi, Sendjaja