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All Journal Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Pengabdian Kepada Masyarakat: Kesehatan (JPKMK) Sinteza Journal Pharmacy of Tanjungpura
Aprianti, Indah
Departemen Teknologi Farmasi, Program Studi Farmasi, Fakultas Kedokteran, Universitas Tanjungpura
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Formulasi Sediaan Emulsi Mengandung Astaxanthin dari Ekstrak Minyak Virgin Coconut Oil Cincalok Indah Aprianti; Siti Nani Nurbaeti; Hadi Kurniawan
Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i1.13635

Abstract

Cincalok is a fermented product made from small shrimps and is a traditional food from West Kalimantan, Indonesia. Cincalok fermentation is produced with the composition of sugar and salt and the appropriate fermentation time. Shrimp in general contain several active compounds, one of which is astaxanthin which gives shrimp its red colour. The shrimp fermentation process resulted in an increase in astaxanthin concentrations compared to ordinary shrimp, caused by the breaking of protein bonds in the fermentation process. Virgin coconut oil is used for astaxanthin extraction because of its good solubility in oil. The emulsion formulation was carried out using 2 different non-ionic emulsifiers to see the effect of the emulsifier on the physical dan chemical properties and stability of the emulsion. Emulsifiers used are cremophor RH 40 and tween 80. The evaluation includes organoleptic testing, determination of content, pH, emulsion type, globule size and distribution of globule size, and viscosity. Stability evaluation were also carried out including volume creaming, centrifugation, heating and cooling, and freeze-thaw tests. The results and data showed that the emulsion formula using emulsifier tween 80 was more physically stable than the formula using cremophor RH 40
POTENSI BAWANG DAYAK (ELEUTHERINE BULBOSA) SEBAGAI SUMBER ANTIOKSIDAN: TINJAUAN LITERATUR Aprianti, Indah
Journal Pharmacy Of Tanjungpura Vol 2, No 2 (2025): APRIL
Publisher : Universitas Tanjungpura

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Abstract

Bawang dayak (Eleutherine bulbosa) merupakan tanaman herbal Indonesia yang telah lama digunakan secara tradisional sebagai obat untuk berbagai penyakit. Tanaman ini mengandung senyawa aktif seperti eleutherin, isoeleutherin, flavonoid, dan senyawa fenolik yang diketahui memiliki aktivitas antioksidan tinggi. Penelitian ini bertujuan untuk meninjau literatur terkait potensi antioksidan E. bulbosa berdasarkan berbagai pendekatan, termasuk studi in vitro, in vivo, dan uji klinis. Aktivitas antioksidan E. bulbosa dilaporkan melalui metode DPPH, FRAP, ABTS, dan pengukuran biomarker stres oksidatif seperti MDA dan TBARS. Studi juga menunjukkan bahwa senyawa aktif yang terkandung dalam tanaman ini bekerja dengan mendonorkan elektron, mengkhelat ion logam, dan menghambat enzim prooksidan. Selain memiliki potensi sebagai sumber antioksidan alami yang kuat, ekstrak E. bulbosa telah diaplikasikan dalam formulasi sediaan oral, topikal, dan kosmetik. Kajian ini menyimpulkan bahwa E. bulbosa adalah kandidat unggul dalam pengembangan produk antioksidan alami dan memerlukan penelitian lanjutan terkait bioavailabilitas dan toksisitas jangka panjang.
TRANSETOSOM UNTUK MENINGKATKAN PENETRASI TRANSDERMAL: REVIEW Aprianti, Indah
Journal Pharmacy Of Tanjungpura Vol 2, No 1 (2024): Oktober
Publisher : Universitas Tanjungpura

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Abstract

Transetosom merupakan sistem pembawa vesikel berbasis lipid yang telah terbukti mampu meningkatkan penetrasi dari zat aktif dalam aplikasi sistem penghantaran transdermal. Karakteristik berupa derajat deformabilitas yang tinggi dari transetosom dapat meningkatkan permeabilitas obat menembus lapisan kulit yang biasanya menjadi hambatan dalam penghantaran zat aktif. Review artikel ini bertujuan untuk memahami kemampuan transetosom untuk meningkatkan penetrasi zat aktif pada sistem penghantaran transdermal dengan membahas mekanisme kerja, formulasi, dan efektivitas transetosom dalam memperbaiki sistem penghantaran transdermal. Berdasarkan penelitian terkini, transetosom menunjukkan potensi yang sangat baik dalam meningkatkan bioavailabilitas obat dan efektivitas terapi berdasarkan sifat fleksibilitas dari vesikel yang memungkinkan penetrasi obat ke dalam lapisan kulit yang lebih dalam, sehingga dapat menjadi solusi yang menjanjikan untuk optimalisasi sistem penghantaran obat transdermal.
Penerapan Swamedikasi Obat Modern dan Obat Tradisional Penyakit Gastritis pada Kader Kesehatan SMAN 12 Pontianak: Implementation of Self-Medication Practices Using Modern and Traditional Medicines for Gastritis Among Health Cadres at SMAN 12 Pontianak Sinaga, Clara Ritawany; Kusharyanti, Indri; Aprianti, Indah
Jurnal Pengabdian Kepada Masyarakat: Kesehatan Vol. 5 No. 4 (2025): Desember
Publisher : Sekolah Tinggi Ilmu Kesehatan Notokusumo Yogyakarta

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Abstract

Abstrak: Gastritis merupakan salah satu gangguan pencernaan yang sering dialami oleh remaja terutama akibat pola makan yang tidak teratur dan stres. Salah satu strategi yang dapat dilakukan untuk mengatasi gejala gastritis ringan adalah melalui pengobatan sendiri. Namun, rendahnya tingkat pengetahuan remaja mengenai penggunaan obat modern dan tradisional untuk gastritis dapat meningkatkan risiko terjadinya medication error. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pemahaman mahasiswa sebagai kader kesehatan mengenai pengobatan sendiri gastritis secara rasional melalui edukasi berbasis terapi farmakologi dan nonfarmakologi. Kegiatan dilaksanakan di SMAN 12 Pontianak dengan melibatkan 25 siswa yang tergabung ke dalam kader kesehatan. Metode pelaksanaan meliputi edukasi klasikal, diskusi, penggunaan alat demonstrasi obat, dan pengisian angket pretest dan posttest untuk mengukur peningkatan pengetahuan. Terjadi peningkatan nilai rata-rata pengetahuan siswa dari 58,8 (pretest) menjadi 77,6 (posttest). Selain itu, tingkat kepuasan terhadap kegiatan mencapai 87,2% yang menunjukkan bahwa metode edukasi diterima dengan baik dan dinilai bermanfaat. Pendidikan pengobatan sendiri gastritis berbasis farmakologi dan bahan alami secara signifikan meningkatkan pengetahuan kader kesehatan siswa. Program ini efektif dan dapat digunakan sebagai model untuk pendidikan serupa di lingkungan sekolah lainnya.   Abstract: Gastritis is one of the most common digestive disorders experienced by adolescents, primarily due to irregular eating habits and stress. One strategy to manage mild gastritis symptoms is self-medication. However, the low level of adolescent knowledge regarding the use of modern and traditional medicines for gastritis can increase the risk of medication errors. This community service activity aimed to enhance students' understanding, as health cadres, of rational self-medication for gastritis through education based on pharmacological and non-pharmacological therapy. The program was conducted at SMAN 12 Pontianak, involving 25 students who serve as school health cadres. The implementation methods included classical education sessions, discussions, the use of drug demonstration tools, and the administration of pre- and post-test questionnaires to measure knowledge improvement. There was an increase in the average student knowledge score from 58.8 (pre-test) to 77.6 (post-test). In addition, the satisfaction rate with the activity reached 87.2%, indicating that the educational methods were well-received and considered beneficial. Pharmacology- and natural product-based self-medication education significantly improved the knowledge of student health cadres. This program proved to be effective and could serve as a model for similar educational initiatives in other school settings.
Pengembangan Yogurt Bunga Telang (Clitoria ternatea L.) menggunakan Pemanis dan Penstabil: Studi Sensoris dan Fisikokimia Indah Aprianti; Robby Najini
Sinteza Vol. 5 No. 2 (2025): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v5i2.30877

Abstract

Yogurt is a fermented dairy product typically produced using lactic acid bacteria such as Lactobacillus bulgaricus and Streptococcus thermophilus. It is widely recognized for its health benefits, particularly in supporting gut microbiota balance. In recent years, incorporating natural ingredients into yogurt formulations has gained increasing attention, as consumers seek functional foods with added health value. One such ingredient is telang flower, which has been recognized for its richness in antioxidants and anthocyanins. Moreover, it contains polyphenolic compounds like catechins, which are associated with improved metabolic activity and increased fat oxidation, potentially supporting weight control. Ongoing innovations in yogurt development aim to enhance its flavor, texture, and stability, often by incorporating sweeteners and thickening agents. This study aimed to evaluate the sensory properties and consumer acceptability of telang flower yogurt formulated with varying concentrations of natural sweetener (honey) and thickening agent/stabilizer (carboxymethyl cellulose, CMC), and to characterize the physical and chemical attributes of the optimum formula. Four formulations were developed using different concentrations of honey (0%, 10%, 15%, and 20%) and CMC (0%, 1%, 1.5%, and 2%). Formulation FIV, consisting of 20% honey and 2% CMC, achieved the highest level of preference among all tested variants. A vibrant purple color, dense texture, pleasantly acidic aroma, and well-balanced sweetness contributed to its superior sensory profile. This formula exhibited favorable physicochemical characteristics, with a pH of 4.34 and a viscosity of 1910 cP. Increasing honey and CMC concentrations were found to improve both consumer acceptability and the overall sensory.
Co-Authors Clara Ritawany Sinaga Hadi Kurniawan Indri Kusharyanti Robby Najini Siti Nani Nurbaeti