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All Journal Jurnal Keperawatan dan Fisioterapi (JKF) Jurnal Penelitian Farmasi dan Herbal Jurnal Pengmas Kestra (JPK)
Debi Dinha Octora Sitepu
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Health Professions Medicine & Pharmacology Nursing Public Health Other

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FORMULATION OF OINTMENT OF ANTIBACTERY ETHANOL EXTRACT OF TORCH GINGER (Etlingera elatior) AGAINST BACTERIA STAPHYLOCOCCUS AUREUS Ainil Fithri Pulungan; Debi Dinha Octora Sitepu; Devi Mariana Sinaga
Jurnal Penelitian Farmasi & Herbal Vol 1 No 1 (2018): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v1i1.30

Abstract

One of the causes of infection was bacteria, such as Staphylococcus aureus. Torch ginger has been widely used to treat dwaseases caused by bacteria. Torch ginger has been studied to have antibacterial activity against Staphylococcus aureus bacteria. The purpose of thwas study was to formulate an ointment preparation of ethanol extract of torch ginger and to see if the ointment preparations had antibacterial activity against Staphylococcus aureus bacteria. The research method used in thwas research was experimental True, covering the stages: making of ethanol extract of kecombrang flower with maceration method using 96% ethanol solvent, ointment formulation made with ointment base: vaseline, adeps lanae, and propylene glycol. Made in three concentrations of extracts namely: F I with 100 mg, F II with 200 mg, and F III with 300 mg. Furthermore, the evaluation of the preparation of evaluation of physical stability and homogeneity, and test of antibacterial activity against Staphylococcus aureus bacteria with diffusion method to use Kirby odor dwasc paper. The results showed that the ointment had good physical stability and homogeneity for 30 days of storage at room temperature. The antibacterial activity test of the ointment shows that the inhibitory diameter F I has an average of 16.45 mm, F II has an average of 18.60 mm and F III has an average of 21.12 mm. Based on the results obtained it can be concluded that the preparation of the ethanol extract of torch ginger has an inhibitory power to Staphylococcus aureus bacteria. In the next research was expected to pay attention to the growing area of ​​torch ginger and to compare the antibacterial activity between petal flowers and flower seeds using Staphylococcus aureus bacteria.
UJI IMUNOMODULATOR DARI EKSTRAK ETANOL DAUN WARU (HIBISCUS TILIACEUS) DENGAN METODE HIPERSENSITIVITAS TIPE LAMBAT Yanna Rotua Sihombing; Debi Dinha Octora
Jurnal Penelitian Farmasi & Herbal Vol 1 No 2 (2019): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v1i2.63

Abstract

Immunomodulator is a compound that can increaase the imuno system. One of the plants that have immunomodulator’s activity is Waru Leaf (Hibiscus tiliaceus). the purpose of this research was to test the effect of immunomodulator by extract of Waru Leaf ethanol on rat male. The activity of immunomodulator was determined by using digital pletysmometer by measuring the differences between the last leg swelling’s volume and the first leg swelling’s volume. The treatment group were divided into 5 groups. Each group consistof 5 rats CMC-Na 0,5% (negative control), Stimuno® 32,5 mg/kgBW (positive control), dose of EEDW 50, 100 and 200 mg/kgBW, and bacteria E.coli as antigen. The results slowed that distribution of EEDW dose 200 mg/kgBW can give the effect of immunostimulant by swelling enthancement compared by CMC-Na 0,5 %. EEDW 200 mg/kgBW that have activity comparable with Stimuno® 32,5 mg/kgBW. Thus, it is concluded that of Waru Leaf extract has immunomodulator effects on delayed-type hypersensitivity response of rat male.
Comparative Effect of Cinnamon Powder and Red Ginger Powder for Menstrual Pain Primary Dysmenorrhea in Adolescent Diah Evawanna Anuhgera; Riris Sitorus; Debi Dinha Octora
JURNAL KEPERAWATAN DAN FISIOTERAPI (JKF) Vol. 5 No. 1 (2022): Jurnal Keperawatan dan Fisioterapi (JKF)
Publisher : Fakultas Keperawatan dan Fisioterapi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jkf.v5i1.1365

Abstract

Menstrual pain is a problem with interferes by women in every menstrual cycle. This can interfere with the activities of women such as dizziness, nausea, stomach cramps, and productivity of women. Several non-pharmacologic treatment can help reduce menstrual pain such as giving cinnamon and red ginger. The purpose of this study was to compare the effectiveness of cinnamon powder and red ginger to decrease menstruation in adolescents with primary dysmenorrhea. This type of research is a quasi-experimental type of time series design. The sample in this study were all first semester female students in the Nursing Study Program at the Lubuk Pakam Medistra Health Institute who experienced primary dysmenorrhea as many as 28 people. The sampling technique used is simple random sampling. In this study there were two groups, namely the control group with the administration of ginger powder while the intervention group with the administration of cinnamon powder. The process was given an intervention for 3 days and the use of the research instrument to measure menstrual pain was the Numeric Rating Scale (NRS). Data analysis used independent t-test and Repeated Measured Anova test. The results showed that there was a difference in mean pain before and before cinnamon powder at 24 hours of intervention after (p<0.001) while red ginger drink powder showed no significant difference in mean pain before and before the intervention in the first 24 hours of intervention (p = 0.112). However, at 48 hours and 72 hours of intervention for the two groups, there was a significant difference in the decrease in mean menstrual pain in primary dysmenorrhea (p<0.001). Cinnamon drink powder is more effective than red ginger drink powder in reducing primary dysmenorrhea menstrual pain. Cinnamon and red ginger can be used as an effective non-pharmacological treatment intervention and obtained as a treatment for primary removal. Midwives can educate and apply the intervention of cinnamon and red ginger drinks to adolescents with primary dysmenorrhea.
SEMINAR ANTIBAKTERI EKSTRAK ETANOL DAUN PACAR AIR (Impatiens balsamina L.) TERHADAP BAKTERI Propionibacterium acne Debi Dinha Octora; Asti Pratiwi; Krismawati Waruwu
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 2 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (279.984 KB) | DOI: 10.35451/jpk.v1i2.894

Abstract

The antibacterial activity of Impatiens balsamina L. has been studied for many years. Water henna leaves contain flavonoids, saponins and tannins which have the ability to inhibit bacterial growth. P. acnes is one type of bacteria that can cause infection in acne. One of the objectives of this study was to determine the antibacterial activity of the ethanol extract of henna water leaves and the most effective concentration in inhibiting P. acnes bacteria. This research is a pure experimental research. Water henna leaves were macerated with 96% ethanol as solvent. Antibacterial activity test was carried out by disc diffusion method. The research was conducted with 3 different concentration variations. The results showed that there was antibacterial activity at each concentration. The conclusion is that the ethanol extract of henna leaves with concentrations of 25%, 50% and 75% gave the most effective bacterial growth inhibition with concentrations of 25%, 50% and 75% which were included in the strong category.
Co-Authors Anuhgera, Diah Evawanna Asti Pratiwi Devi Mariana Sinaga Fithri Pulungan, Ainil Krismawati Waruwu Riris Sitorus Yanna Rotua Sihombing