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SOLID BATH SOAP DOSAGE FORMULATIONS OF THE ETHANOL EXTRACT OF FRESH FRUIT OF MORINDA (MORINDA CITRIFOLIA L.) Yanna Rotua Sihombing; Aminah Syarifudin; Rinaldo Berutu
Jurnal Penelitian Farmasi & Herbal Vol 1 No 1 (2018): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v1i1.60

Abstract

Morinda plants grow widely throughout the Pasipic and are one of the most significant sources of traditional medicine among the Pacific island community. Morindas contain natural antioxidants for skin health and saponins in the manufacture of soap. Morindas also has potential as an antibacterial (Flavanoid). The purpose of this research is to formulate the ethanol extract of the fruit of morinda (Morinda citrifolia L.) fresh bath soap. Preparations to become solid. This research uses experimental methods. Morinda fruit is extracted by a process of maceration. Solid bath soap preparations inspection conducted this research is test the pH with a concentration of 2,5%, 3,5% and 4,5%. Ethanol extract of the fruit of morindas can be preparations soap formulations in bath with solid inspection results show pH, pH range between 8,5-10,1 show that the solid bath soaps are qualified solid bath soap. The result showed solid bath soap preparations from ethanol extract of the fruit of morinda (Morinda citrifolia L.) fresh with variations in defferent concentrations can be formulated in to a solid bath soap.
UJI IMUNOMODULATOR DARI EKSTRAK ETANOL DAUN WARU (HIBISCUS TILIACEUS) DENGAN METODE HIPERSENSITIVITAS TIPE LAMBAT Yanna Rotua Sihombing; Debi Dinha Octora
Jurnal Penelitian Farmasi & Herbal Vol 1 No 2 (2019): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v1i2.63

Abstract

Immunomodulator is a compound that can increaase the imuno system. One of the plants that have immunomodulator’s activity is Waru Leaf (Hibiscus tiliaceus). the purpose of this research was to test the effect of immunomodulator by extract of Waru Leaf ethanol on rat male. The activity of immunomodulator was determined by using digital pletysmometer by measuring the differences between the last leg swelling’s volume and the first leg swelling’s volume. The treatment group were divided into 5 groups. Each group consistof 5 rats CMC-Na 0,5% (negative control), Stimuno® 32,5 mg/kgBW (positive control), dose of EEDW 50, 100 and 200 mg/kgBW, and bacteria E.coli as antigen. The results slowed that distribution of EEDW dose 200 mg/kgBW can give the effect of immunostimulant by swelling enthancement compared by CMC-Na 0,5 %. EEDW 200 mg/kgBW that have activity comparable with Stimuno® 32,5 mg/kgBW. Thus, it is concluded that of Waru Leaf extract has immunomodulator effects on delayed-type hypersensitivity response of rat male.
SOSIALISASI AKTIVASI ZONA HAMBAT DAUN PIRDOT (SAURAIA VULCANI KORTH) TERHADAP CANDIDA ALBICANS Romauli Anna Teresia Marbun; Yanna Rotua Sihombing
JURNAL ANTARA ABDIMAS KEPERAWATAN Vol 4 No 2 (2021): Jurnal Antara Abdimas Keperawatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (299.536 KB) | DOI: 10.37063/abdimaskep.v4i2.604

Abstract

Pendahuluan: Penyakit akibat infeksi jamur menjadi penyakit dominan iklim tropis. Indonesia yang beriklim tropis memiliki lingkungan dengan penduduk banyak dan tingkat sosial ekonomi yang rendah. Candida albicans merupakan jamur penyebab kandidiasis dan penyebab sariawan, vulvavaginistis, dan kandiduria. Daun ini menjadi kandidat tumbuhan berpotensi antijamur. Metode: Metode pengujian menggunakan metode difusi dengan menggunakan pencadang kertas. Penelitian yang dilaksanakan tersebut menggunakan ketokonazol sebagai pembanding. Hasil dari pengujian dilakukan disosialisasikan kepada mahasiswa Farmasi. Hasil:. Manfaat dari pirdot menjadi perhatian di pandemic sekarang ini. Budidaya tumbuhan pirdot dapat dilakukan sendiri sehingga dapat digunakan untuk terapi komplementer. Melihat hasil uji aktivitas antibakteri yang termasuk antibakteri kategori sedang. Kesimpulan: Daun pirdot dapat menjadi tumbuhan berpotensi antijamu ke depana dan menjadi kandidat obat tradisional. Hal ini menjadi penting untuk landasan penelitian selanjutnya untuk menghasilkan penelitian terkait produk antijamur ke depan
THE ADOLESCENT LEVEL OF KNOWLEDGE OF SELF-MEDICATION IN SIMPANG SELAYANG NEIGHBORHOODS, MEDAN Romauli Anna Teresia Marbun; Klara Jeina Br Tarigan; Yanna Rotua Sihombing
JURNAL KESMAS DAN GIZI (JKG) Vol. 5 No. 2 (2023): Jurnal Kesmas dan Gizi (JKG)
Publisher : Fakultas Kesehatan Masyarakat Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jkg.v5i2.1690

Abstract

Self-medication is the most common action taken before finally deciding to see a doctor. Self-medication is known as self medication or self-medication is defined as a treatment effort using drugs purchased at pharmacies or drug stores freely without a prescription from a doctor. Self-medication is done because it is sufficient to treat health problems experienced, for example, illnesses with mild symptoms and can heal themselves in a short time such as pain, fever, cough, cold, and minor injuries. Drugs without a doctor's prescription such as free and limited free drugs are relatively safe to use for self-medication.This type of research is quantitative analytical research with descriptive. This study is to determine the level of knowledge of self-medication in adolescents in Simpang Selayang Village by approaching, observing or collecting data at once and providing education. Based on questionnaire data, it is known that the gender of female adolescents has a higher level of knowledge of self-medication than male adolescents. It can be concluded that the age level of late adolescents has a higher level of knowledge of self-medication than early adolescents. In this study, the level of knowledge of the last education of higher education towards self-medication is higher than those who have the last education either elementary, junior high or high school. The study concluded that the level of knowledge of students towards self-medication was higher than other occupations. The level of knowledge of self-medication practices in adolescents in Simpang Selayang is classified as good (62.0%).
SOSIALISASI AKTIVITAS DAYA HAMBAT EKSTRAK DAUN PIRDOT (SAURAIA VULCANI KORTH.) TERHADAP PERTUMBUHAN CANDIDA ALBICANS Romauli Anna teresia Marbun; Jhon Patar Sinurat; Saadah Siregar; Yanna Rotua Sihombing
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 2 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (364.125 KB) | DOI: 10.35451/jpk.v1i2.731

Abstract

Penyakit infeksi jamur menjadi perhatian khusus di berbagai negara dengan iklim tropis. Indonesia dengan iklim tropis disebabkan oleh udara yang lembab, dan sanitasi yang masih kurang. Indonesia memiliki lingkungan yang padat penduduk dan tingkat sosial ekonomi yang rendah. Jamur Candida albicans merupakan jamur penyebab kandidiasis dan penyebab sariawan, lesi pada kulit, vulvavaginistis, candida pada urin (kandiduria), dan gastrointestinal kandidiasis. Salah satu jenis tanaman yang berkhasiat sebagai obat yaitu pirdot (Sauraia vulcani Korth.) dan bagian yang biasanya digunakan adalah bagian daun. Penelitian sebelumnya ekstrak daun pirdot memiliki aktivitas menghambat pertumbuhan jamur Candida albicans. Konsentrasi daun pirdot 80% memiliki aktivitas daya hambat terhadap jamur yang paling efektif. Penelitian yang dilaksanakan tersebut menggunakan ketokonazol sebagai pembanding. Budidaya tumbuhan pirdot dapat dilakukan sendiri sehingga dapat digunakan untuk keperluan pribadi di tengah pandemic sekarang ini. Sasaran dari sosialisasi ini adalah mahasiswa Farmasi Institut Kesehatan MEDISTRA Lubuk Pakam. Hal ini menjadi penting untuk landasan penelitian selanjutnya untuk menghasilkan penelitian terkait produk antijamur ke depan
SEMINAR TENTANG IDENTIFIKASI DRPs PADA PASIEN GERIATRI YANG MENERIMA RESEP POLIFARMASI PADA PENYAKIT STROKE Yanna Rotua Sihombing; Asti Pratiwi; Yosi Darmirani
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 2 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (485.848 KB) | DOI: 10.35451/jpk.v1i2.739

Abstract

This study aims to determine the presence of DRPs in geriatric patients who are prescribed polypharmacy in stroke patients. This study is a prospective study with data presented descriptively. Data were obtained from medical records, drug information cards and patient interviews. The results of this study were 41 patients who were used as subjects. There were 3 people (7.32%) experienced DRPs and 38 people (92.68%) did not experience DRPs. Of the seven categories of DRPs, there were only 2 categories of DRPs, category 1, namely congenital drug therapy that was not localized (2.44%) and category 2, which was the incidence of too high a dose (4.88%)
WORKSHOP OF TESTING THE EFFECTIVENESS OF ANTIBACTERIAL EXTRACT OF SURUHAN (peperomia pellucida l. Kunth) LEAVES AGAINST staphylococcus epidermidis BACTERIA Novandi Purba; Yanna Rotua
JURNAL PENGMAS KESTRA (JPK) Vol. 2 No. 1 (2022): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (296.326 KB) | DOI: 10.35451/jpk.v2i1.1120

Abstract

Skin infections or dermatitis are included in the ten most common diseases in Indonesia, so the use of antibiotics is very high. The increasing use of antibiotics will cause an increase in the use of inappropriate antibiotics. The purpose of this research and community service was to find out the leaf extract of suruhan (Peperomia pellucida L. Kunth) with a variety of solvents providing anti-microbial activity against Staphylococcus epidermidis bacteria and conveying information to the public about the leaf extract that can be used as an acne medication. The results showed that the inhibition of ethanol extract and aquadest leaves of suruhan against the growth of Staphylococcus epidermidis bacteria at a concentration of 25 mg/mL clear zone 6.0 mm ethanol extract and 5.4 mm aquadest extract (Potentially Weak), concentration 50 mg/mL diameter of the extract inhibition zone ethanol 8.46 mm and aquadest extract 6.53 mm (medium potential), concentration 75 mg/mL diameter of inhibition zone 12.96 mm ethanol extract and 8.53 mm aquadest extract (strong potential). From the research data obtained, it is socialized to the public regarding the antibacterial activity of the leaves of suruhan against Staphylococcus epidermidis bacteria. The purpose of Community Service (PKM) is to provide information to the public that suruhan leaves can be used as an antibacterial to inhibit bacterial growth even with various types of solvent concentrations used. The conclusion in this study is that there are many plants that can be used to inhibit the growth and development of acne-causing bacteria, one of which is the leaf plant among young people.