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All Journal Majalah Kedokteran Nusantara The Journal Of Medical School
Sanusi Piliang
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Health Professions Medicine & Pharmacology

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Hubungan kadar hematokrit dengan tingkat keparahan pada preeklamsia berat di RSUP H Adam Malik Medan, RSUD dr. Pirngadi Medan dan RS jejaring FK USU M. Wahyu Wibowo; R. Haryono Roeshadi; Sarma Lumbanraja; Sanusi Piliang; M. Khuwailid; Deri Edianto
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 47, No 1 (2014): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Abstract

Introduction : Hypertension in pregnancy is one of the causes of maternal morbidity and mortality is high. It cause of 30-40% of perinatal deaths. This state is related to blood viscosity and hematocrit is an important determinant of the blood viscosity. Careful observation of the several indicators, such as hematocrit levels can prevent from unwanted circumstances. Methods : This research is to design pre test - post interventions to determine the relationship between hematocrit levels in preeclampsia before and after childbirth. Pre and post test data is performed using the t test (t-test) and to find the relationship of hematocrit levels with the degree of preeclampsia with Chi-square test.Results : Of the total 55 cases, most cases of severe preeclampsia occurs in the age group 21-35 years were 43 cases (78.2%) cases, have never given birth were 22 cases (40%), history of antenatal care is often enough (4 - 8x during pregnancy) that is found in 30 cases (54.5%), gestational age at term 30 cases (54.5%), and delivery baby with a normal weight in 29 cases (52.7%). Hematocrit levels showed a significant reduction in the time before and after 24 hours of delivery of 34.018 + 0.690 percent to 30.140 ± 0.656 percent (p<0.001). There were no significant differences in hematocrit levels based on the severity of severe preeclampsia both before birth and after 24 hours of labor (p>0.05).Discussion : Found a significant difference in hematocrit levels at the time before and after 24 hours of delivery. Hematocrit levels not influenced by the severity of severe preeclampsia.Keywords : Severe preeclampsia; hematocrit levels
Kadar Kortisol Saliva Sebagai Penanda Gangguan Gejala Menopause pada Paramedis Poli Rawat Jalan Usia Perimenopause di Rumah Sakit Umum Pusat Haji Adam Malik Medan Yufi Permana; M. Fidel Ganis Siregar; Syamsul A. Nasution; Sanusi Piliang; Muldjadi Affendy; Yostoto B. Kaban
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 48, No 1 (2015): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Introduction :The premenopausal period is characterized as a decline in estrogen levels that consequently result in disturbing symptoms. One noted significant factor in this period is the psychological state, a condition that is closely related to cortisol levels. Stress is known to be a product of the neuroendocrine system. As a product of tbis mechanism, cortisol is frequently used as a biomarker to study stress. Currently, menopausal symptoms are diagnosed based on present complaints, which tends to be subjective, consequently, a biomarker is required to diagnose menopausal disturbances. Method :This analytic, diagnostic, cross sectional study was conducted in the General Hiospital of Haji Adam Malik Medan, and enrolled paramedics working at the out patient clinic from March until April 2015. All subjects were asked to fill a Menopause Rating Scale (MRS), the results of which were then associated with obtained salivary cortisol levels. Results :Salivary cortisol levels was significantly associated with menopausal disturbances with p< 0.01. Salivary cortisol also significantly differed based on each MRS scores with p=0.008. A cut-off value of 9.52 ng/ml was obtained, with specificity and sensitivity values of 85 and 77%, respectively. Conclusion :Salivary cortisol testing as a marker for menopausal disturbances obtained a marker of 9.52 ng/mL with specificity and sensitivity values of 85 and 77%, respectively. Key words :Salivary cortisol, menopausal disturbances, Menopause Rating Scale
Co-Authors Deri Edianto M. Fidel Ganis Siregar M. Khuwailid M. Wahyu Wibowo Muldjadi Affendy R. Haryono Roeshadi Sarma Lumbanraja Syamsul A. Nasution Yostoto B. Kaban Yufi Permana