Muldjadi Affendy
Unknown Affiliation

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

Perbandingan berat badan pada akseptor kontrasepsi hormonal oral kombinasi sebelum, sesudah 6 bulan dan 12 bulan penggunaan Dewi Andriyati; Rusli P. Barus; Khairani Sukatendel; Muldjadi Affendy; Henry Salim Siregar; Johny Marpaung
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 47, No 3 (2014): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background : Hormonal contraceptive is the most effective and reversible contraceptive method to prevent a pregnancy. Combined hormonal oral contraceptive primarily work by preventing ovulation. Ovulation was blocked by an action in hypothalamushypophyse-ovarium axys to reduce luteinizing hormone (LH) dan folicle-stimulating hormone (FSH). One of side effect of combined hormonal oral contraceptive pill use is increase the body weight, especially in the first year of use. Because of this side effect can lead to noncompliance or discontinuation of COCs, it takes knowledge of the patients about the side effects that can occur and how to prevent it.Methods : This study is observational analytic, which uses secondary data from medical records of family planning acceptors who use combined hormonal oral contraceptive pill for at least 12 months which is carried out in December 2014 - January 2015 in Public Health Center Helvetia Medan.Results : Mean value of maternal body weight before use of combined hormonal oral contraceptive pill is 57.35 kg, after 6 months of use is 58 kg, and after 12 months of use is 58.28 kg. Based on these results, with the paired t-test between maternal body weight before and after 6 months of use, it gets p value <0.05, which means there is a significant difference between body weight before and after 6 months use of combined hormonal oral contraceptive pill. In the paired t-test comparing the maternal body weight before and after 12 months of use, it gets p value <0.05, which showed a significant difference between body weight before and after 12 months use of combined hormonal oral contraceptive pill. And paired t-test comparing body weight after 6 months and 12 months of use, it gets p value <0.05, which means there is a significant difference between body weight after 6 months and after 12 months use of combined hormonal oral contraceptive pill.Conclusion : There is a significant maternal weight gain before, after 6 months and after 12 months use of combined hormonal oral contraceptive pill.Keywords : body weight, oral contraceptive, family planning
Kadar Kortisol Saliva Sebagai Penanda Gangguan Gejala Menopause pada Paramedis Poli Rawat Jalan Usia Perimenopause di Rumah Sakit Umum Pusat Haji Adam Malik Medan Yufi Permana; M. Fidel Ganis Siregar; Syamsul A. Nasution; Sanusi Piliang; Muldjadi Affendy; Yostoto B. Kaban
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 48, No 1 (2015): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction :The premenopausal period is characterized as a decline in estrogen levels that consequently result in disturbing symptoms. One noted significant factor in this period is the psychological state, a condition that is closely related to cortisol levels. Stress is known to be a product of the neuroendocrine system. As a product of tbis mechanism, cortisol is frequently used as a biomarker to study stress. Currently, menopausal symptoms are diagnosed based on present complaints, which tends to be subjective, consequently, a biomarker is required to diagnose menopausal disturbances. Method :This analytic, diagnostic, cross sectional study was conducted in the General Hiospital of Haji Adam Malik Medan, and enrolled paramedics working at the out patient clinic from March until April 2015. All subjects were asked to fill a Menopause Rating Scale (MRS), the results of which were then associated with obtained salivary cortisol levels. Results :Salivary cortisol levels was significantly associated with menopausal disturbances with p< 0.01. Salivary cortisol also significantly differed based on each MRS scores with p=0.008. A cut-off value of 9.52 ng/ml was obtained, with specificity and sensitivity values of 85 and 77%, respectively. Conclusion :Salivary cortisol testing as a marker for menopausal disturbances obtained a marker of 9.52 ng/mL with specificity and sensitivity values of 85 and 77%, respectively. Key words :Salivary cortisol, menopausal disturbances, Menopause Rating Scale