Article Per Year (5 Year)
p-Index From 2020 - 2025
1.066
P-Index
This Author published in this journals
All Journal Jurnal Sains dan Teknologi Farmasi Journal of Science and Applicative Technology JFL : Jurnal Farmasi Lampung Mejuajua Jurnal Vokasi Kesehatan
Isna Mulyani
Program Studi Farmasi, Akademi Farmasi Cendikia Farma Husada Bandar Lampung
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Earth & Planetary Sciences Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Other

Published : 7 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 7 Documents
Search

 1 
Uji Sitotoksik Ekstrak dan Fraksi Daun Jati (Tectona Grandis Linn. F.) dengan Metoda Brine Shrimp Lethality Bioassay Alen, Yohannes; Akhsanita, Mardha; mulyani, Isna; Susanti, Meri
Jurnal Sains dan Teknologi Farmasi Vol 17 No 2 (2012)
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

he Study of cytotoxic effects of the methanolic extract and the fraction of Teak’s leave (Tectona grandis Linn. f.) by using Brine Shrimp Lethality Bioassay Method had been done. Results showed that the methanolic extract have cytotoxic level of (LC50) 16,58 ppm, n-hexane fraction 21,83 ppm, ethyl acetate fraction 21,31 ppm and residue fraction 21,27 ppm, respectively.
FORMULASI DAN EVALUASI FISIK SAMPO ANTIOKSIDAN DARI EKSTRAK UBI JALAR UNGU (Ipomoea Batatas L.) Arsy Fauziah; Isna Mulyani; Rizki Nisfi Ramdhini
JFL : Jurnal Farmasi Lampung Vol. 10 No. 1 (2021): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/10.37090/jfl.v9i1.325

Abstract

Oksidasi bisa terjadi bukan hanya pada kulit saja melainkan rambut juga bisa mengalamiproses oksidasi. Paparan sinar UV-A, UV-B, polutan dan bahan kimia yang digunakanpada rambut berpotensi untuk menyebabkan oksidasi. Antosianin diketahui memiliki efekantioksidan karena merupakan senyawa turunan flavonoid. Penelitian ini bertujuan untukmengembangkan formula sampo yang mengandung ekstrak ubi jalar ungu sebagaisumber antioksidan. Formula dibuat dengan menggunakan bahan natrium lauril sulfat,NaCl, propilen glikol, metil dan rpopil paraben dan ekstrak ubi jalar ungu. Optimasi sediaanhanya dilakukan pada variasi konsentrasi NaCl sebagai peningkat viskositas di konsentrasi2%, 3% dan 4%. Evaluasi sediaan meliputi uji organoleptik, pH, bobot jenis, dayapembersihan, tinggi dan stabilitas busa. Sediaan memiliki pH yang memenuhi rentangpersyaratan sediaan maupun stabilitas antosianin. Perbandingan tinggi busa pada waktu20 menit terhadap waktu 1 menit yang dihasilkan oleh formula 1,2,3 berturut-turut 1 ; 0,8dan 0,5. Bobot jenis yang dihasilkan sediaan pada formula 1, 2, 3 secara berturut-turutadalah 1,0409 ; 1,1 dan 1,116 . Sampo dengan formula 2 yang dengan variasi NaCl padakonsentrasi 3% secara aplikasi paling nyaman untuk digunakan karena memilikikekentalan paling sesuai.Kata Kunci: Sampo antioksidan, ubi jalar, antosianin.
SKRINING FITOKIMIA DAN ANALISIS KROMATOGRAFI LAPIS TIPIS EKSTRAK KULIT PISANG KEPOK Isna Mulyani; Rizki Nisfi Ramdhini; Syaikhul Aziz
JFL : Jurnal Farmasi Lampung Vol. 10 No. 1 (2021): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v10i1.495

Abstract

Kepok banana peel is an organic waste that has potential to be reused. Several studies proofed that banana peels have antioxidant activity, antimicrobial, inhibit the formation of cholesterol crystals and gallstones, diuretic effect, and mutagenic effect. This study aims to identify secondary metabolites contained in kepok banana peels using qualitative test methods (phytochemical screening) and thin layer chromatography analysis. The results of the phytochemical screening of kepok banana peel indicated the presence of alkaloids, monoterpenes/sesquiterpenes, phenols/tannins, saponins,and quinones. Thin layer chromatographic profile of ethanol extract showed the presence of flavonoid, phenol, and quinone compounds.Keywords: Phytochemical, chromatography, banana peel
TELAAH FITOKIMIA KULIT KACANG TANAH (Arachis hypogaea, L). Rizki Nisfi Ramdhini; Isna Mulyani; Syaikhul Aziz
JFL : Jurnal Farmasi Lampung Vol. 10 No. 1 (2021): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v10i1.498

Abstract

Peanut peel are a waste product of the peanut processing industry with little commercial value. Some of studies have been conducted indicating peanut peel can be beneficial as a source for traditional medicinal products since it is also rich of antioxidants. The aim of this research was to identify the content of secondary metabolites on the peanut peel. The method used was maseration with 96% ethanol. Phytochemical screening and assaying were performed using thin layer chromatography (TLC) method. The results of TLC analysis showed that the secondary metabolites in peanut peel were positive for flavonoids, alkaloids, tannins and quinon. Keywords: Peanut peel, Phytochemical, Thin-Layer chromatography (TLC)
Quantitative Profiling of Total Flavonoid Content in Cassava Leaf (Manihot esculenta Crantz) Varieties and Isolation of Flavonoid Compounds from a High-Flavonoid Variety Aziz, Syaikhul; Siringoringo, Vinta Marito; Mulyani, Isna; Ngatinem
Journal of Science and Applicative Technology Vol. 9 No. 1 (2025): Journal of Science and Applicative Technology June Chapter
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat (LPPM), Institut Teknologi Sumatera, Lampung Selatan, Lampung, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35472/jsat.v9i1.2190

Abstract

Cassava (Manihot esculenta Crantz) is widely utilized across Indonesia as both a staple food and a traditional medicinal resource, and its leaves are known to contain bioactive secondary metabolites such as flavonoids. This study aimed to quantify the total flavonoid content in several cassava leaf varieties and to isolate a flavonoid compound from the variety with the highest flavonoid content. Total flavonoid content was determined using UV-Visible spectrophotometry. The isolation of flavonoid compounds was carried out using vacuum liquid chromatography (VLC) and column chromatography (CC), with thin-layer chromatography (TLC) employed to monitor the separation results. The total flavonoid content of the Gajah, UJ-3 (Thailand), UJ-5 (Katsesart), Cimanggu dan Kaspro varieties were found to be 1.029 ± 0.003 mgQE/g, 0.746 ± 0.006 mgQE/g, 0.970 ± 0.009 mgQE/g, 0.936 ± 0.004 mgQE/g and 1.220 ± 0.003 mgQE/g, respectively. The Kaspro variety exhibited the highest flavonoid content. Isolation and characterization of the flavonoid from Kaspro leaves yielded a yellowish powder with absorption maxima at 269 nm (Band II) and 334 nm (Band I). Further analysis using shift reagents identified the isolated compound as apigenin, a member of the flavone group.
Acute Toxicity Studies of Mirabilis jalapa L. Flower Extract in Mice Mulyani, Isna; Desy Purnama Sari; Muhammad F. Agustiawan; Syaikhul Aziz
Jurnal Vokasi Kesehatan Vol 4 No 1 (2025)
Publisher : Gayaku Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58222/juvokes.v4i1.1375

Abstract

Traditional medicine, derived from medicinal plants, has been used for generations as a form of treatment. The safety, quality, and efficacy of plants used for medicinal purposes are important considerations. Mirabilis jalapa L., also known as the four o'clock flower, is a traditional medicine with known benefits such as diuretic, anti-inflammatory, and antibacterial properties. However, its safety level remains uncertain. To address this, an acute toxicity test was conducted on the ethanol extract of Mirabilis jalapa L. flowers to determine its safety. The extraction process utilized a reflux method with 96% alcohol as a solvent, resulting in a standardized extract. Subsequent toxicity tests were performed on 12 female white mice, using doses of 300 and 2,000 mg/kg body weight. The results revealed an LD50 value exceeding 2,000 mg/kg body weight for the ethanol extract of Mirabilis jalapa L. flowers, indicating its classification as "Practically Not Toxic."
Edukasi dan Pelatihan Pembuatan Minuman Fungsional Anti Anemia di SMA 2 Muhammadiyah Bandar Lampung Nurnahari, Naura; Aziz, Syaikhul; Fauziyya, Riri; Nur Auli, Winni; Maulidia Rahayyu, Annisa; Kartika Sari Ramadhani, Untia; Azanti Putri, Refsya; Fajar Fauzi, Muh; Sekarsari Yusuf, Mubarika; Mulyani, Isna
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 5 No. 1 (2025): Agustus 2025
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52622/mejuajuajabdimas.v5i1.236

Abstract

Anemia adalah suatu kondisi di mana jumlah sel darah merah atau konsentrasi Hemoglobin di dalam darah lebih rendah dari normal. Berdasarkan Survei Kesehatan Nasional Indonesia 2023, prevalensi anemia pada kelompok  usia 15-24 tahun sebesar 15,5%. Anemia bisa dicegah dengan nutrisi yang tepat. Tujuan pengabdian masyarakat ini adalah mengedukasi para remaja mengenai pemanfaatan bahan alam untuk mencegah anemia serta pelatihan pembuatan minuman fungsional untuk mencegah anemia. Kegiatan ini berlangsung di SMA 2 Muhammadiyah Bandar Lampung dan melibatkan 39 siswa-siswi. Metode yang diterapkan dalam kegiatan ini meliputi ceramah dan demonstrasi. Penilaian peningkatan pengetahuan dilakukan melalui pre-test dan post-test. Evaluasi dilakukan menggunakan instrumen pre-test dan post-test yang terdiri dari 10 butir pertanyaan. Uji normalitas Shapiro-Wilk menunjukkan bahwa data berdistribusi normal (pre-test p = 0,7485; post-test p = 0,2501), sehingga dilanjutkan dengan uji paired sample t-test. Hasil analisis menunjukkan peningkatan yang signifikan secara statistik (p = 0,0008), dengan rata-rata skor meningkat dari 59,3% menjadi 80,5%.
Co-Authors Arsy Fauziah Fajar Fauzi, Muh Fauziyya, Riri Kartika Sari Ramadhani, Untia Mardha Akhsanita Maulidia Rahayyu, Annisa Meri Susanti Muhammad F. Agustiawan Ngatinem Nur Auli, Winni Nurnahari, Naura Refsya Azanti Putri Rizki Nisfi Ramdhini Rizki Nisfi Ramdhini Rizki Nisfi Ramdhini Sekarsari Yusuf, Mubarika Siringoringo, Vinta Marito Syaikhul Aziz Yohannes Alen