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Pelatihan deteksi dini kanker payudara pada masyarakat dan kader Posbindu PTM di RW 8 Kelurahan Air Putih Kecamatan Tampan Kota Pekanbaru Tuti Restuastuti; Viviyanti Viviyanti; Ridha Restila; Ilhami Romus
Unri Conference Series: Community Engagement Vol 1 (2019): Seminar Nasional Pemberdayaan Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/unricsce.1.368-374

Abstract

Breast cancer is the most frequent cancer among women. WHO data states that in 2018 an estimated 627,000 women die from breast cancer or approximately 15% of all cancer deaths among women. However, the survival of patients with breast cancer is quite high when detected early. Posbindu PTM RW 08 Air Putih is a posbindu guided by FK UNRI to prevent and control non-communicable diseases, including breast cancer. Therefore, increasing the ability of Posbindu PTM cadres to conduct BSE socialization (Self Breast Examination) is necessary. The form of community service is BSE training in the community and Posbindu PTM cadres. In addition, participants were facilitated for examinations by specialist doctors. The activity was attended by 16 participants, beginning with the material about Posbindu PTM, breast cancer, BSE practice and screening for participants who have symptoms of breast cancer. Evaluation of activities was assessed by active participation and community response to the question and answer session. Participants can also re-practice BSE. The results of the examination of three participants who were examined by a doctor, suspected (suspect) 1 person FAM, 1 person Carcinoma mammae, and 1 other person did not. The suspected participants were suggested to immediately conduct a clinical examination and ask the RW to help them obtaining BPJS.
Efek Inhibitor Proteasom Terhadap Gambaran Histopatologi Jantung pada Tikus yang diinduksi Aterosklerosis Ilhami Romus; Ismawati Ismawati; Indah Putri Arwandi
Jurnal Ilmu Kedokteran Vol 17, No 1 (2023): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v17i1.2023.66-70

Abstract

Proteasome inhibitors are compounds that can inhibit the proteasome pathway in carrying out its functions. Proteasome inhibitors have a beneficial effect due to their anti-inflammatory properties. The proteasome inhibitor used in this study was bortezomib. This study aimed to analyze the effect of proteasome inhibitors on cardiac histopathology in atherosclerosis-induced rats. This study used male Rattus novergicus Wistar strain which was divided into 3 groups, namely the control group, the atherosclerosis-induced group and the atherosclerosis-induced group and given bortezomib. The results obtained the mean scores of edema, inflammation and necrosis in the atherosclerosis group were given bortezomib at a dose of 50 g/kgBW were less than the atherosclerosis group. Theese difference were statistically significant  (p<0.05). This study concluded that the administration of bortezomib can reduce the Impact of atherosclerotic lesions on the heart muscle.