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All Journal Jurnal Kedokteran Anatomica (Anatomica Medical Journal) Sumatera Medical Journal
Feriyawati, Lita
Department Of Anatomy, Faculty Of Medicine, Universitas Sumatera Utara, Medan, Indonesia
Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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The Effect of Torbangun Leaves Tea on Msg-induced Fetal Develop-ment Disorder in Mice M.Kes, Sufitni; Feriyawati, Lita; Pane, Yunita Sari; Lelo, Aznan
Sumatera Medical Journal Vol. 2 No. 1 (2019): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (472.383 KB) | DOI: 10.32734/sumej.v2i1.717

Abstract

The safety of MSG on the fetus has not been confirmed yet. The objective of this research is to determine the effect of tea of torbangun leaves on fetal development disorder of mice. The present study is experimental with a Completely Randomized Design (CRD). Data obtained were then analyzed by ANOVA, with p<0,05 as the level of significant. The comparison of mean values ± SEM increase number of live fetuses group C1-T1 (4,60 ± 0,93; 11,40 ± 0,87), p=0,018. The comparison of mean values ± SEM decrease number of embryo re-sorption percentage group C0-C1 (00,00 ± 00,00; 36,74 ± 15,13), group C1-C2 (36,74 ± 15,13; 00,00 ± 0,00), group C1-T1 (36,74 ± 15,13; 00,00 ± 0,00), and group C1-T2 (36,74 ± 15,13; 15,00 ± 22,36), p=0,020. This study concluded that T1 group is giving the best effect on increasing life fetuses and decreasing embryo re-sorption percentage.
Gambaran Sitologi Large Cell Carcinoma Paru Dwi Rita Anggraini; Lita Feriyawati
ANATOMICA MEDICAL JOURNAL | AMJ Vol 1, No 1 (2018)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.241 KB) | DOI: 10.30596/anatomica

Abstract

AbstrakLarge cell carcinoma (LCC) merupakan suatu udifferentiated non-small cell carcinoma adalah subtipe dari kanker paru yang tidak dijumpai gambaran small cell carcinoma (SCLC), adenocarcinoma (ADC), maupun squamous cell carcinoma (SQC). Aplikasi sitologi paru yang  relevan saat ini adalah dalam mendiagnosa dan penanganan kanker paru. Sekitar 70% kanker paru didiagnosis pada stadium lanjut dan tidak dapat diobati.Pada artikel ini, dilaporkan gambaran sitologi dari LCC. Laporan kasus seorang pria usia 54 tahun yang secara klinis diduga karsinoma bronkus, kemudian dilakukan brushing bronkus. Pemeriksaan sitologi  menunjukkan kelompokan sel-sel tumor yang hiperseluler, membentuk pola syncytia-like sheets, dengan batas antar sel tidak jelas. Sel-sel tumor pleomorfik, dijumpai giant sel, inti bulat sampai irregular, beberapa dijumpai binukleasi, kromatin kasar, anak inti menonjol, sitoplasma eosinofilik. Hasil pemeriksaan sitologi suatu LCC. Prognosa umumnya buruk, reseksi komplet pada stadium I atau II, angka ketahanan hidup diperkirakan berkisar antara 0%-21%. Kata kunci : large cell carcinoma, kanker paru, undifferentiated non-small cell carcinoma,  sitologi.  AbstractLarge cell carcinoma (LCC) as an undifferentiated non-small cell carcinoma is a merely descriptive term indicating a subtype of lung cancer with no specific features of small-cell lung cancer (SCLC), adenocarcinoma (ADC) or squamous cell carcinoma (SQC). The most relevant application of lung cytology today is in the diagnosis and management of lung cancer; approximately 70% of those cancers are diagnosed at a late stage and are unresectable. We investigated the cytology smear of large cell carcinoma. The case report of a  54 years old man, clinically diagnosed with suspected carcinoma bronchus. The cytology features from brushing bronchus showed hypercellularity of cell tumor arranged in cellular aggregates or syncytia-like sheets of large cells with indistinct cell borders. The cells are extreme pleomorphisme, bizarre tumor giant cells,  nuclei round to irregular, sometimes binuclei with vesicular chromatin and prominent nucleoli, with eosinosophilic cytoplasm. The result of cytology evaluated were Large Cell Carcinoma. The prognosis was poorly, completely resection of stage I or II, the survival rate was estimated to range between  0% to 21%.  Key words: large cell carcinoma, lung cancer, undifferentiated non-small cell carcinoma,  cytology.
Co-Authors Anggraini, Dwi Rita Aznan Lelo Lubis, Rodiah Rahmawaty Sufitni Tengku Siti Harilza Zubaidah Yunita Sari Pane