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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Jurnal Kedokteran Anatomica (Anatomica Medical Journal) ORBITA: Jurnal Pendidikan dan Ilmu Fisika Indonesian Journal of Medicine Sumatera Medical Journal IJOEP : International Journal of Ecophysiology SCRIPTA SCORE Scientific Medical Journal Essential: Essence of Scientific Medical Journal Jurnal Kedokteran Ibnu Nafis
Anggraini, Dwi Rita
Department Of Anatomy, Faculty Of Medicine Universitas Sumatera Utara, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences

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Effects of Bean Ethanol Extract (Phaseolus Vulgaris L.) on Superoxide Dismutase Activity in Wistar Mice (Micetus Norvegicus) Hyperglycemia Sinaga, Ade Putra Fratama; Ilyas, Syafruddin; Anggraini, Dwi Rita
Indonesian Journal of Medicine Vol 2, No 2 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (276.398 KB)

Abstract

Background: Aloxan tetrahyd micee causes free radicals and higher reactive oxidative species (ROS) production, being able to lead to reduce insulin secretion from pancreatic β cells and receptor sensitivity in insulin-receptor cells resulting in hyperglycemia conditions. Bean extract ethanol can reduce oxidative stress. The purpose of this study was to determine bean’s ethanol extract effectiveness in lowering blood sugar levels and increasing the activity of superoxide dismutase (SOD) enzyme.Subjects and Methods: This was a randomized controlled trial (RCT) study. The samples were mice (Micetus norvegicus) of wistar strains randomized in five groups: P1-negative control, positive P2-control, P-3 ethanol extract group of 200mg / kgBW, P4-group 400mg / kgBW, P5-group 600 mg / kgBW. Dependent variables are blood sugar (mg/ dL) and superoxide dismutase enzymes. The independent variable is the bean extract of ethanol. Differences in blood sugar levels and superoxide enzyme levels of intergroup dismutase were tested by Anova test, followed by post hoc test, to determine the effectiveness of bean extract ethanol.Results: This study showed a statistically significant decrease in blood glucose levels after ethanol extract of green beans 600 mg / kg BW from day 14 to day 28 (p <0.05). This study did not show a decrease in blood sugar levels after ethanol extract of green beans 200 mg / kgBW and 400 mg / kgBW from day 7 until day 28 (p> 0.05). Giving ethanol extract of green beans did not affect the activity of superoxide dismutase enzyme (p = 0.830).Conclusion: Giving ethanol extract of green beans 600 mg / kgBW effectively decrease blood sugar in male wistar mice (Micetus norvegicus) from day 14 to day 28. Giving ethanol extract of green beans 200 mg/ kgBW, 400 mg / kgBW, and 600 mg / kgBW, is not effective to increase the activity of superoxide dismutase enzyme.Keywords: Phaseolus Vulgaris L., blood sugar level, superoxide dismutase enzymeCorrespondence: Ade Putra Fratama Sinaga. Masters Program on Biomedics, Faculty of Medicine, North Sumatra University. Email: adeputra535@ymail.com.Indonesian Journal of Medicine (2017), 2(2): 139-145https://doi.org/10.26911/theijmed.2017.02.02.08
Active learning method for health life implementation in new normal era in Tanjung Sari Medan Tri Widyawati; Siti Syarifah; Yunita Sari Pane; Daulay, Milahayati; Dwi Rita Anggraini
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 5 No. 2 (2020): ABDIMAS TALENTA : Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (523.372 KB) | DOI: 10.32734/abdimastalenta.v5i2.5099

Abstract

COVID-19 or Corona Virus Disease 2019 is a virus which has been endemic in 2020 worldwide and has been declared a pandemic by WHO. The spread of virus is fast sharply with an increase in cases every day, including in Medan City. Ten of the sub-districts are destined as the red zone, including Tanjung Sari Village, which is located in Medan Selayang District. The lack of health promotion related to the appropiate use of drugs and changes to a hygienic lifestyle need education in facing the life of the new normal era nowadays. Therefore, community service activities related to education using the Instant Active Learning / Cara Belajar Insan Aktif (CBIA) method need to be carried out to prevent and to deal with the spread of COVID-19. This activity was carried out by providing education materials both in the form of powerpoint and videos to twenty housewives in Tanjung Sari village. The participants were evaluated before and after the program by giving questionnaire to asses their knowledge and uderstanding. The contents of education including the COVID-19 spread prevention way, selfprotection tools, general knowledge to use medicines correctly and a hygienic lifestyle. The materials were delivered by the CBIA method. Data from evaluation were analysed by T-dependent test, p <0.05 was considered significant. The results showed that the characteristics of the participants as follows: 9 participants aged 21-30 years (45%), 17 people worked as housewives (85%), as many as 12 people having high school or vocational education level (60%). There was a significant effect on the provision of education on participants' knowledge (p <0.05). This program gained participants knowledge and understanding on prevention way of COVID-19, the correct use of medicines and hygienic lifestyle.
The Relationship of Knowledge, Attitude, and Behavior to Taking Care of External Genitalia with Leucorrhea Incident in The Darul Hikmah Islamic Boarding School Student Zahra, Khairina; Anggraini, Dwi Rita
Sumatera Medical Journal Vol. 3 No. 3 (2020): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v3i3.3318

Abstract

Introduction. Reproduction organ is one of the sensitive organ in the body and need special care. Personal hygiene habit is one of the important factor to avoid infection. It is because infection can cause vaginal discharge and cervical carcinoma. Tropical climate in Indonesia lead about 90% of girl teenagers to potentially have vaginal discharge causing bacteria, fungi, and virus easily grow. Objectives. To identify the relationship between knowledge, attitude, and behavior of taking care of external genitalia with vaginal discharge incident on students at Pondok Pesantren Modern Darul Hikmah. Methods. This is a descriptive analytical study with cross sectional design. The data was taken with primary data. Results. Leucorrhoea incidence rate at 103 respondents are 60,2% of normal vaginal discharge and 38,9% of abnormal vaginal discharge. There is a correlation between knowledge of taking care of external genitalia with vaginal discharge (p=0,001). There is correlation between attitude of taking care of external genitalia with vaginal discharge (p=0,018). There is correlation between behavior of taking care of external genitalia with vaginal discharge (p=0,002). Conclusion. There is correlation between knowledge, attitude, and behavior of taking care of external genitalia with vaginal discharge incident on students at Pondok Pesantren Modern Darul Hikmah.
Gambaran Sitologi Large Cell Carcinoma Paru Dwi Rita Anggraini; Lita Feriyawati
ANATOMICA MEDICAL JOURNAL | AMJ Vol 1, No 1 (2018)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.241 KB) | DOI: 10.30596/anatomica

Abstract

AbstrakLarge cell carcinoma (LCC) merupakan suatu udifferentiated non-small cell carcinoma adalah subtipe dari kanker paru yang tidak dijumpai gambaran small cell carcinoma (SCLC), adenocarcinoma (ADC), maupun squamous cell carcinoma (SQC). Aplikasi sitologi paru yang  relevan saat ini adalah dalam mendiagnosa dan penanganan kanker paru. Sekitar 70% kanker paru didiagnosis pada stadium lanjut dan tidak dapat diobati.Pada artikel ini, dilaporkan gambaran sitologi dari LCC. Laporan kasus seorang pria usia 54 tahun yang secara klinis diduga karsinoma bronkus, kemudian dilakukan brushing bronkus. Pemeriksaan sitologi  menunjukkan kelompokan sel-sel tumor yang hiperseluler, membentuk pola syncytia-like sheets, dengan batas antar sel tidak jelas. Sel-sel tumor pleomorfik, dijumpai giant sel, inti bulat sampai irregular, beberapa dijumpai binukleasi, kromatin kasar, anak inti menonjol, sitoplasma eosinofilik. Hasil pemeriksaan sitologi suatu LCC. Prognosa umumnya buruk, reseksi komplet pada stadium I atau II, angka ketahanan hidup diperkirakan berkisar antara 0%-21%. Kata kunci : large cell carcinoma, kanker paru, undifferentiated non-small cell carcinoma,  sitologi.  AbstractLarge cell carcinoma (LCC) as an undifferentiated non-small cell carcinoma is a merely descriptive term indicating a subtype of lung cancer with no specific features of small-cell lung cancer (SCLC), adenocarcinoma (ADC) or squamous cell carcinoma (SQC). The most relevant application of lung cytology today is in the diagnosis and management of lung cancer; approximately 70% of those cancers are diagnosed at a late stage and are unresectable. We investigated the cytology smear of large cell carcinoma. The case report of a  54 years old man, clinically diagnosed with suspected carcinoma bronchus. The cytology features from brushing bronchus showed hypercellularity of cell tumor arranged in cellular aggregates or syncytia-like sheets of large cells with indistinct cell borders. The cells are extreme pleomorphisme, bizarre tumor giant cells,  nuclei round to irregular, sometimes binuclei with vesicular chromatin and prominent nucleoli, with eosinosophilic cytoplasm. The result of cytology evaluated were Large Cell Carcinoma. The prognosis was poorly, completely resection of stage I or II, the survival rate was estimated to range between  0% to 21%.  Key words: large cell carcinoma, lung cancer, undifferentiated non-small cell carcinoma,  cytology.
DAYA ANTIBAKTERI EKSTRAK BUAH BELIMBING WULUH (Averrhoa bilimbi Linn) TERHADAP Methicillin Resistant Staphylococcus aureus Ricky Alexander Chandra; Rina Yunita; Dian Dwi Wahyuni; Dwi Rita Anggraini
Essence of Scientific Medical Journal Vol 16 No 1 (2018): Volume 16 No. 1 (Januari-Juni) : Essence Of Scientific Medical Journal
Publisher : Kelompok Ilmiah Hippocrates Fakultas Kedokteran Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/ESTL.2018.v16.i01.p08

Abstract

Background: Staphylococcus aureus become resistant against several group of antibiotics such as penicillins, aminoglycosides, and quinolones. Current world concern is antibiotic resistance to Methicillin Resistant Staphylococcus aureus (MRSA) because these cases are still increasing. The high incidende of infectious disease and antibiotic resistance become a challenge to find out new, effective, alternative antibiotics. Bilimbi fruit contains bioactive compounds such as flavonoids, saponins, and tannins. The bioactive compounds are proven as natural antibacterial. Aims: To determine antibacterial activity of bilimbi fruits extract against MRSA. Methods: Bilimbi fruit were collected from a garden at Tanjung Mulia, Medan. Bilimbi fruits were extracted by using maceration method with 96% ethanol as solvent. Antibacterial activity was tested with well-diffusion method. Wells are made by using a sterile cork borer with 6 mm in diameter. Treatments are divided into 6 groups, 6,25%, 12,5%, 25% and 50% bilimbi fruits extract, positive control (chloramphenicol 2% ointment) and negative control (dimethylsulfoxide). Each group is repeated four times. Results: Average inhibitory zone diameter concentration of 6.25% is 15.150 ± 0,310 mm, concentration of 12.5% ??is 18.075 ± 0,309 mm, concentration of 25% is 20.225 ± 0,680 mm, and concentration of 50% is 24.375 ± 2,209 mm. Inhibitory zone of each group is analyzed with Kruskal-Wallis test. Results showed all groups have significant differences. Conclusions: Bilimbi fruits ethanolic extract had antibacterial activity against MRSA. The best concentration of bilimbi fruits extract to inhibit the growth of MRSA is 50%.
ANALISIS EFFECT SIZE PENGARUH MODEL PROBLEM BASED LEARNING TERHADAP KETERAMPILAN BERPIKIR KRITIS DAN PEMECAHAN MASALAH DALAM PEMBELAJARAN SAINS Dwi Anggraini Harita Putri; Nurul Fauziah; Westi Widia Wati
ORBITA: Jurnal Kajian, Inovasi dan Aplikasi Pendidikan Fisika Vol 8, No 2 (2022): November
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (216.808 KB) | DOI: 10.31764/orbita.v8i2.10295

Abstract

ABSTRAKPenelitian ini bertujuan untuk melihat dampak dari penerapan model pembelajaran problem based learning terhadap keterampilan berpikir kritis dan pemecahan masalah peserta didik dalam pembelajaran IPA dan Fisika. Jenis penelitian yang digunakan merupakan meta-analisis yang menganalisis sebanyak 20 jurnal yang terdiri dari 1 jurnal internasional dan 19 jurnal nasional yang telah ada sejak lima tahun terakhir. Teknik analisis data pada penelitian ini yaitu dengan mencari nilai effect size untuk masing-masing jurnal. Berdasarkan hasil penelitian yang didapatkan diketahui bahwa model problem based learning berpengaruh terhadap keterampilan berpikir kritis dengan nilai rerata effect size sebesar 1,3 dan pemecahan masalah memiliki rerata nilai effect size sebesar 1,16 yang keduanya termasuk kedalam kategori sangat tinggi pada pembelajaran IPA dan Fisika. Berdasarkan jenjang Pendidikan nilai dampak terbesar diperoleh pada jenjang Sekolah Dasar dengan kategori sangat tinggi untuk keterampilan berpikir kritis dan dampak terbesar untuk keterampilan pemecahan masalah dampak tertinggi diperoleh pada jenjang Sekolah Menengah Pertama. Berdasarkan tingkatan kelas pada jenjang Pendidikan dampak tertinggi yaitu pada kelas V Sekolah Dasar berkategori sangat tinggi dan berdasarkan mata pelajaran dampak tertinggi yaitu pada mata pelajaran IPA. Sehingga diketahui bahwa penerapan model pembelajaran problem based learning terhadap keterampilan berpikir kritis dan pemecahan masalah peserta didik dalam pembelajaran IPA dan Fisika menghasilkan pengaruh dan dampak yang tinggi. Kata kunci: meta analisis; pbl; berpikir kritis; pemecahan masalah. ABSTRACTThis study aims to see the impact of the application of the problem based learning model on students' critical thinking and problem solving skills in learning science and physics. The type of research used is a meta-analysis that analyzes 20 journals consisting of 1 international journal and 19 national journals that have been around for the last five years. The data analysis technique in this study is to find the effect size value for each journal. Based on the research results, it is known that the problem-based learning model has an effect on critical thinking skills with an average effect size value of 1.3 and problem solving has an average effect size value of 1.16, both of which are included in the very high category in science and physics learning. Based on the level of education, the greatest impact value was obtained at the elementary school level with a very high category for critical thinking skills and the largest impact for problem-solving skills. The highest impact was obtained at the junior high school level. Based on the grade level at the Education level, the highest impact is in class V Elementary School, which is categorized as very high and based on the highest impact subject, namely in science subjects. So that it is known that the application of the problem based learning model to students' critical thinking and problem-solving skills in learning science and physics produces high influence and impact. Keywords: meta-analysis; pbl; critical thinking; problem-solving.
Hubungan Durasi Penggunaan Visual Display Terminal Terhadap Computer Vision Syndrome pada Mahasiswa Fakultas Kedokteran Universitas Sumatera Utara Vincent Wijaya; Dwi Rita Anggraini; Fitriani Lumongga; Rosmayanti Syafriani Siregar
SCRIPTA SCORE Scientific Medical Journal Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v4i2.10534

Abstract

Pendahuluan. Computer Vision Syndrome merupakan sekumpulan gejala penglihatan yang disebabkan oleh paparan Visual Display Terminal berupa computer, smartphone, dan lain lain dalam jangka waktu yang lama. Mahasiswa selama pembelajaran daring terpapar Visual Display Terminal dalam jangka waktu yang panjang, membuat mereka rentan terkena Computer Vision Syndrome. Tujuan. Penelitian ini bertujuan untuk mengetahui pengaruh durasi penggunaan Visual Display Terminal terhadap Computer Vision Syndrome pada mahasiswa Fakultas Kedokteran Universitas Sumatera Utara. Metode. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross-sectional. Penelitian dilakukan di Fakultas Kedokteran Universitas Sumatera Utara pada bulan Agustus 2022. Sampel penelitian yaitu Mahasiswa aktif Fakultas Kedokteran Universitas Sumatera Utara tahun ajaran 2019-2021 diperoleh dengan stratified random sampling. Hasil. Analisis data penelitian menggunakan uji korelasi spearman’s rho rank correlation. Penelitian menunjukkan terdapat adanya hubungan signifikan durasi penggunaan VDT terhadapat CVS (p = 0.03) dengan nilai korelasi yang lemah (d = 0.314). Kesimpulan. Ada hubungan durasi penggunaan lebih dari empat jam secara terus menerus atau pengunaan VDT selama 6 jam terhadap Computer Vision Syndrome, dengan sumber VDT yang paling sering digunakan adalah smartphone.
Immunomodulatory Effect of Ethanol Extract of Pirdot Leaf (Saurauia vulcani Korth ) on CD4+ and IL-2 Hepatic Profile in Tyfoid Fever Haslinda; Rina Amelia; Muhammad Ichwan; Dwirita Anggraini; Yunita Sari Pane
International Journal of Ecophysiology Vol. 5 No. 1 (2023): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v5i1.12315

Abstract

Typhoid fever is an acute febrile disease caused by Salmonella typhi bacteria that is obtained orally either through food or from drinks.Many immunological activities that occur due to salmonella infection so that immunomodulators are needed to speed up the healing of one of them by using pirdot leaves. Pirdot leaves are widely distributed in Indonesia, especially in the Lake Toba area of North Sumatra.This plant has many bioactive components, one of which is flavonoids.The flavonoid component of pirdot Leaf has been widely studied and is believed to improve the immune system because it is able to increase the production of IL-2 which is involved in the activation and proliferation of lymphocyte cells and can increase T CD4 cells. T CD4+ it self is a signal transduction marker in the mechanism of typhoid fever that can activate Antigen Precenting Cell (APC) to provide resistance to foreign substances.
Optimization of Nutrition Improvement of Preschool Children in the Pandemic Era in Taman Bermain Tabitha, Deli Serdang Mega Sari Sitorus; Nenni Dwi Aprianti Lubis; Dwi Rita Anggraini; Yoan Carolina Panggabean
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 1 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v8i1.10190

Abstract

The state of good nutrition affects children's health which has a long lasting impact on forming a healthy generation of Indonesians. Nutritional problems, one of which is stunting, is a problem that is of concern to the state, this situation can be caused by lack of knowledge of the mother or inadequate intake. One of the efforts that can be made to overcome is prepared community service at the Tabitha Deli Serdang Playground in the form of nutritional counseling activities, giving healthy food, demonstrations of healthy food processing and making proper hand washing facilities. The problems reported at partner locations was stunting case were found and health service facilities was distant. Data collection on mother's knowledge about nutrition and healthy food was also carried out through filling out questionnaires before and after service. It was found that all mother's knowledge increased significantly after counseling.
Factors Affecting Junior High School Students' 4C Skills: An Empirical Study Dwi Anggraini Harita Putri; Usmeldi Usmeldi
Jurnal Penelitian Pendidikan IPA Vol 9 No SpecialIssue (2023): UNRAM journals and research based on science education, science applic
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9iSpecialIssue.5793

Abstract

The purpose of this research is to find out factors that can affecting Junior High School Students' 4C Skills such as self-efficacy, learning motivation, liveliness, mathematical literacy, and scientific literacy can significantly influence students' 4C skills. This study is quantitative research using a survey method. In addition, the effect of each construct on the 4C skills is estimated through the Partial Least Square Structural Equation Model (PLS-SEM). The research results show that self-efficacy, scientific literacy, learning motivation and activeness have a significant effect on 4C skills. Mathematical literacy does not have a significant effect on 4C skills, but scientific literacy has a mediating effect on the relationship between mathematical literacy and 4C skills. Therefore, it is expected that students will further improve their skills in realizing the demands of globalization.
Co-Authors Caesar, Fahrezi Daulay, Milahayati Feriyawati, Lita Fitriani Lumongga Haslinda ira Cinta Lestari Lubis, Nenni Dwi Aprianti Muhammad Ichwan Nurul Fauziah Pasaribu, Saadatur Rizqillah Ricky Alexander Chandra Rina Amelia Rina Yunita Rosmayanti Syafriani Siregar Sinaga, Ade Putra Fratama Siti Syarifah Sitorus, Mega Sari Suryani Eka Mustika Syafruddin Ilyas Tamara Lubis Tri Widyawati Usmeldi Usmeldi Vincent Wijaya Westi Widia Wati Yoan Carolina Panggabean Yunita Sari Pane Zahra, Khairina